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Smilax china L. rhizome extract inhibits nuclear factor-κB and induces apoptosis in ovarian cancer cells.
Hu LL, Chen DS, Wang YY, Qin Y, Huang P, Yu LX, Liao J, Hua XL. Hu LL, et al. Chin J Integr Med. 2015 Dec;21(12):907-15. doi: 10.1007/s11655-014-1788-9. Epub 2014 Dec 16. Chin J Integr Med. 2015. PMID: 25511428
OBJECTIVE: To study the antitumor effects and associated mechanisms of extract of the Smilax china L. rhizome (SCR) on ovarian cancer cells. METHODS: Ovarian cancer cells A2780 were treated with different concentrations of SCR extract (SCRE), and compa …
OBJECTIVE: To study the antitumor effects and associated mechanisms of extract of the Smilax china L. rhizome (SCR) on ovarian …
Smilax china L.: A review of its botany, ethnopharmacology, phytochemistry, pharmacological activities, actual and potential applications.
Wang M, Bai QX, Zheng XX, Hu WJ, Wang S, Tang HP, Yu AQ, Yang BY, Kuang HX. Wang M, et al. J Ethnopharmacol. 2024 Jan 10;318(Pt B):116992. doi: 10.1016/j.jep.2023.116992. Epub 2023 Aug 3. J Ethnopharmacol. 2024. PMID: 37541403 Review.
ETHNOPHARMACOLOGICAL RELEVANCE: Smilax china L., an extensively used traditional Chinese medicine, is known as Baqia in China. ...MATERIALS AND METHODS: This article uses "Smilax china L." "S. china" as the keyword and collects rel …
ETHNOPHARMACOLOGICAL RELEVANCE: Smilax china L., an extensively used traditional Chinese medicine, is known as Baqia in Chi
Smilax china root extract as a novel Glucose- 6-phosphate dehydrogenase inhibitor for the treatment of hepatocellular carcinoma.
Kanwal L, Ali S, Rasul A, Tahir HM. Kanwal L, et al. Saudi J Biol Sci. 2022 Oct;29(10):103400. doi: 10.1016/j.sjbs.2022.103400. Epub 2022 Jul 30. Saudi J Biol Sci. 2022. PMID: 35991850 Free PMC article.
Moreover, the anticancer activity evaluation against HepG2 cells determined Smilax china as a potent inhibitor of cancer cells (IC(50) value of 16.017 mug/ml). The acute and subacute toxicities were not observed in mice with various concentrations (50, 100, 2 …
Moreover, the anticancer activity evaluation against HepG2 cells determined Smilax china as a potent inhibitor of cancer
Scopolin obtained from Smilax china L. against hepatocellular carcinoma by inhibiting glycolysis: A network pharmacology and experimental study.
Wang C, Zhou Q, Wu ST. Wang C, et al. J Ethnopharmacol. 2022 Oct 5;296:115469. doi: 10.1016/j.jep.2022.115469. Epub 2022 Jun 16. J Ethnopharmacol. 2022. PMID: 35718053
ETHNOPHARMACOLOGICAL RELEVANCE: Smilax china L. is a well-known traditional medicinal plant. In China, it is a common anti-cancer drug that has been inherited for thousands of years. Some in vitro and in vivo studies have confirmed its potential lipid- …
ETHNOPHARMACOLOGICAL RELEVANCE: Smilax china L. is a well-known traditional medicinal plant. In China, it is a common a …
Diosgenin: An Updated Pharmacological Review and Therapeutic Perspectives.
Semwal P, Painuli S, Abu-Izneid T, Rauf A, Sharma A, Daştan SD, Kumar M, Alshehri MM, Taheri Y, Das R, Mitra S, Emran TB, Sharifi-Rad J, Calina D, Cho WC. Semwal P, et al. Oxid Med Cell Longev. 2022 May 29;2022:1035441. doi: 10.1155/2022/1035441. eCollection 2022. Oxid Med Cell Longev. 2022. PMID: 35677108 Free PMC article. Review.
Plants including Rhizoma polgonati, Smilax china, and Trigonella foenum-graecum contain a lot of diosgenin, a steroidal sapogenin. ...This review aims to provide an overview of the in vitro, in vivo, and clinical studies reporting the diosgenin's pharmacologi …
Plants including Rhizoma polgonati, Smilax china, and Trigonella foenum-graecum contain a lot of diosgenin, a steroidal sapoge …
Anti-metastatic effect of Smilax china L. extract on MDA-MB-231 cells.
Nho KJ, Chun JM, Kim HK. Nho KJ, et al. Mol Med Rep. 2015 Jan;11(1):499-502. doi: 10.3892/mmr.2014.2698. Epub 2014 Oct 17. Mol Med Rep. 2015. PMID: 25333945
Cancer metastases are not always cured by chemotherapy. Conventional and alternative drugs, including Chinese herbal remedies, have been developed to target metastatic cancer cells. Smilax china L. (SCL), a member of the Smilacaceae family, exerts anti
Cancer metastases are not always cured by chemotherapy. Conventional and alternative drugs, including Chinese herbal remedies, have b
Effect of Smilax china L.-containing serum on the expression of POLD1 mRNA in human hepatocarcinoma SMMC-7721 cells.
Cao B, Zhang Z, Zhang Y, Li J, Liang G, Ling J. Cao B, et al. Exp Ther Med. 2013 Oct;6(4):1070-1076. doi: 10.3892/etm.2013.1264. Epub 2013 Aug 19. Exp Ther Med. 2013. PMID: 24137319 Free PMC article.
Bock greenbrier rhizome, also known as Smilax china L. rhizome, induces heat clearing and detoxification and dispels wind dampness. Additionally, this Chinese medicine has been shown to function as an anticancer compound in various types of cancer. The aim of …
Bock greenbrier rhizome, also known as Smilax china L. rhizome, induces heat clearing and detoxification and dispels wind damp …
Diosgenin: Recent Highlights on Pharmacology and Analytical Methodology.
Jesus M, Martins AP, Gallardo E, Silvestre S. Jesus M, et al. J Anal Methods Chem. 2016;2016:4156293. doi: 10.1155/2016/4156293. Epub 2016 Dec 28. J Anal Methods Chem. 2016. PMID: 28116217 Free PMC article. Review.
Diosgenin, a steroidal sapogenin, occurs abundantly in plants such as Dioscorea alata, Smilax China, and Trigonella foenum graecum. This bioactive phytochemical not only is used as an important starting material for the preparation of several steroidal drugs in the …
Diosgenin, a steroidal sapogenin, occurs abundantly in plants such as Dioscorea alata, Smilax China, and Trigonella foenum gra …
A flavonoid glycoside isolated from Smilax china L. rhizome in vitro anticancer effects on human cancer cell lines.
Li YL, Gan GP, Zhang HZ, Wu HZ, Li CL, Huang YP, Liu YW, Liu JW. Li YL, et al. J Ethnopharmacol. 2007 Aug 15;113(1):115-24. doi: 10.1016/j.jep.2007.05.016. Epub 2007 May 18. J Ethnopharmacol. 2007. PMID: 17606345
The anticancer activity of eight crude extracts of Smilax china L. rhizome (SCR) against HeLa cells was assessed by MTT assay and clonogenic assay, the fraction rich in flavonoids had show good activity against HeLa cells. ...We evaluated its in vitro cytotoxicity a …
The anticancer activity of eight crude extracts of Smilax china L. rhizome (SCR) against HeLa cells was assessed by MTT assay …
Mitochondrial apoptosis contributes to the anti-cancer effect of Smilax glabra Roxb.
Gao Y, Su Y, Qu L, Xu S, Meng L, Cai SQ, Shou C. Gao Y, et al. Toxicol Lett. 2011 Nov 30;207(2):112-20. doi: 10.1016/j.toxlet.2011.08.024. Epub 2011 Sep 3. Toxicol Lett. 2011. PMID: 21920417
Smilax glabra Roxb. (SGR), a member of the Smilacaceae family and a rhizome of the Liliaceae plant, has shown anti-inflammation and detoxification properties, and a few studies reported its anti-cancer effect. In this study, we showed that SGR inhibited growth of hu
Smilax glabra Roxb. (SGR), a member of the Smilacaceae family and a rhizome of the Liliaceae plant, has shown anti-inflammation and d
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