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Page 1
Did you mean sodium glucose cotransport dehydration (121 results)?
Syndrome of Inappropriate Antidiuresis: From Pathophysiology to Management.
Warren AM, Grossmann M, Christ-Crain M, Russell N. Warren AM, et al. Endocr Rev. 2023 Sep 15;44(5):819-861. doi: 10.1210/endrev/bnad010. Endocr Rev. 2023. PMID: 36974717 Free PMC article. Review.
In the absence of severe symptoms requiring urgent intervention, fluid restriction (FR) is widely endorsed as the first-line treatment for SIAD in current guidelines, but there is considerable controversy regarding second-line therapy in instances where FR is unsucc …
In the absence of severe symptoms requiring urgent intervention, fluid restriction (FR) is widely endorsed as the first-line treatmen …
Diabetic Ketoacidosis: Evaluation and Treatment.
Veauthier B, Levy-Grau B. Veauthier B, et al. Am Fam Physician. 2024 Nov;110(5):476-486. Am Fam Physician. 2024. PMID: 39556629 Review.
However, hyperglycemia has been de-emphasized in recent guidelines because of the increasing incidence of euglycemic DKA. The use of sodium-glucose cotransporter-2 inhibitors modestly increases the risk of DKA and euglycemic DKA. ...Amylase, lipase, hepatic t …
However, hyperglycemia has been de-emphasized in recent guidelines because of the increasing incidence of euglycemic DKA. The use of sodi …
Management of diabetic ketoacidosis.
Barski L, Golbets E, Jotkowitz A, Schwarzfuchs D. Barski L, et al. Eur J Intern Med. 2023 Nov;117:38-44. doi: 10.1016/j.ejim.2023.07.005. Epub 2023 Jul 5. Eur J Intern Med. 2023. PMID: 37419787 Review.
These controversies may include issues such as optimal fluid resuscitation, rate and type of Insulin therapy, potassium and bicarbonate replacement. ...Factors like pregnancy, renal disease, congestive heart failure, acute coronary syndrome, older age, use of sod …
These controversies may include issues such as optimal fluid resuscitation, rate and type of Insulin therapy, potassium and bi …
Diuretics in States of Volume Overload: Core Curriculum 2022.
Novak JE, Ellison DH. Novak JE, et al. Am J Kidney Dis. 2022 Aug;80(2):264-276. doi: 10.1053/j.ajkd.2021.09.029. Epub 2022 Feb 19. Am J Kidney Dis. 2022. PMID: 35190215 Review.
Volume overload, defined as excess total body sodium and water with expansion of extracellular fluid volume, characterizes common disorders such as congestive heart failure, end-stage liver disease, chronic kidney disease, and nephrotic syndrome. ...Separately, clin …
Volume overload, defined as excess total body sodium and water with expansion of extracellular fluid volume, characterizes com …
Atrasentan in Patients with IgA Nephropathy.
Heerspink HJL, Jardine M, Kohan DE, Lafayette RA, Levin A, Liew A, Zhang H, Lodha A, Gray T, Wang Y, Renfurm R, Barratt J; ALIGN Study Investigators. Heerspink HJL, et al. N Engl J Med. 2025 Feb 6;392(6):544-554. doi: 10.1056/NEJMoa2409415. Epub 2024 Oct 25. N Engl J Med. 2025. PMID: 39460694 Clinical Trial.
(An exploratory stratum of patients who were receiving a sodium-glucose cotransporter 2 inhibitor were included in a separate analysis.) Safety analyses were based on adverse events across the entire main stratum. ...The percentage of patients with adverse ev …
(An exploratory stratum of patients who were receiving a sodium-glucose cotransporter 2 inhibitor were included in a se …
Diuretics in pediatrics.
Lava SAG, Zollinger C, Chehade H, Schaffner D, Sekarski N, Di Bernardo S. Lava SAG, et al. Eur J Pediatr. 2023 May;182(5):2077-2088. doi: 10.1007/s00431-022-04768-2. Epub 2023 Jan 3. Eur J Pediatr. 2023. PMID: 36595088 Review.
Newer diuretic classes like vaptans and sodium glucose type 2 cotransporter inhibitors, the recent controversies on hydrochlorothiazide, and the issue of diuretic resistance, will also be briefly addressed. ...WHAT IS KNOWN: Diuretics are frequently prescri …
Newer diuretic classes like vaptans and sodium glucose type 2 cotransporter inhibitors, the recent controversies on hyd …
Management of Heart Failure Patient with CKD.
Banerjee D, Rosano G, Herzog CA. Banerjee D, et al. Clin J Am Soc Nephrol. 2021 Jul;16(7):1131-1139. doi: 10.2215/CJN.14180920. Epub 2021 Jan 25. Clin J Am Soc Nephrol. 2021. PMID: 33495289 Free PMC article. Review.
Evidence for treatment with beta-blockers, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, angiotensin receptor neprilysin inhibitors, and sodium-glucose cotransporter inhibitors in mild-to-moderate CKD has emerged from general popula …
Evidence for treatment with beta-blockers, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, angiotensin receptor nep …
Classic diabetic ketoacidosis and the euglycemic variant: Something old, something new.
Mehta AE, Zimmerman R. Mehta AE, et al. Cleve Clin J Med. 2025 Jan 2;92(1):33-39. doi: 10.3949/ccjm.92a.24075. Cleve Clin J Med. 2025. PMID: 39746727 Free article. Review.
However, patients with type 2 diabetes may present with DKA, usually with higher blood glucose levels and milder ketoacidosis. With the increased use of sodium-glucose cotransporter 2 (SGLT-2) inhibitors, the variant euglycemic DKA has been described. …
However, patients with type 2 diabetes may present with DKA, usually with higher blood glucose levels and milder ketoacidosis. With t …
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues.
Fang Z, Raza U, Song J, Lu J, Yao S, Liu X, Zhang W, Li S. Fang Z, et al. ESC Heart Fail. 2025 Apr;12(2):1059-1080. doi: 10.1002/ehf2.14947. Epub 2024 Jul 22. ESC Heart Fail. 2025. PMID: 39034866 Free PMC article. Review.
Metabolic aging drives intricate shifts in glucose and lipid metabolism, leading to insulin resistance, mitochondrial dysfunction and lipid accumulation within cardiomyocytes. ...Key approaches include senomorphics and senolytics to limit senescence, antioxidants targeting …
Metabolic aging drives intricate shifts in glucose and lipid metabolism, leading to insulin resistance, mitochondrial dysfunction and …
A Randomized Trial of Empagliflozin to Increase Plasma Sodium Levels in Patients with the Syndrome of Inappropriate Antidiuresis.
Refardt J, Imber C, Sailer CO, Jeanloz N, Potasso L, Kutz A, Widmer A, Urwyler SA, Ebrahimi F, Vogt DR, Winzeler B, Christ-Crain M. Refardt J, et al. J Am Soc Nephrol. 2020 Mar;31(3):615-624. doi: 10.1681/ASN.2019090944. Epub 2020 Feb 4. J Am Soc Nephrol. 2020. PMID: 32019783 Free PMC article. Clinical Trial.
BACKGROUND: Treatment options to address the hyponatremia induced by the syndrome of inappropriate antidiuresis (SIAD) are inadequate. The sodium glucose cotransporter 2 (SGLT2) inhibitor empagliflozin promotes osmotic diuresis via urinary glucose excr …
BACKGROUND: Treatment options to address the hyponatremia induced by the syndrome of inappropriate antidiuresis (SIAD) are inadequate. The …
247 results