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Gut mucosal cells transfer α-synuclein to the vagus nerve.
Chandra R, Sokratian A, Chavez KR, King S, Swain SM, Snyder JC, West AB, Liddle RA. Chandra R, et al. Among authors: sokratian a. JCI Insight. 2023 Dec 8;8(23):e172192. doi: 10.1172/jci.insight.172192. JCI Insight. 2023. PMID: 38063197 Free PMC article.
Mouse α-synuclein fibrils are structurally and functionally distinct from human fibrils associated with Lewy body diseases.
Sokratian A, Zhou Y, Tatli M, Burbidge KJ, Xu E, Viverette E, Donzelli S, Duda AM, Yuan Y, Li H, Strader S, Patel N, Shiell L, Malankhanova T, Chen O, Mazzulli JR, Perera L, Stahlberg H, Borgnia M, Bartesaghi A, Lashuel HA, West AB. Sokratian A, et al. Sci Adv. 2024 Nov;10(44):eadq3539. doi: 10.1126/sciadv.adq3539. Epub 2024 Nov 1. Sci Adv. 2024. PMID: 39485845 Free PMC article.
Anionic Nanoplastic Contaminants Promote Parkinson's Disease-Associated α-Synuclein Aggregation.
Liu Z, Sokratian A, Duda AM, Xu E, Stanhope C, Fu A, Strader S, Li H, Yuan Y, Bobay BG, Sipe J, Bai K, Lundgaard I, Liu N, Hernandez B, Rickman CB, Miller SE, West AB. Liu Z, et al. Among authors: sokratian a. Res Sq [Preprint]. 2023 Oct 13:rs.3.rs-3439102. doi: 10.21203/rs.3.rs-3439102/v1. Res Sq. 2023. Update in: Sci Adv. 2023 Nov 15;9(46):eadi8716. doi: 10.1126/sciadv.adi8716. PMID: 37886561 Free PMC article. Updated. Preprint.
Pathological α-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain.
Xu E, Boddu R, Abdelmotilib HA, Sokratian A, Kelly K, Liu Z, Bryant N, Chandra S, Carlisle SM, Lefkowitz EJ, Harms AS, Benveniste EN, Yacoubian TA, Volpicelli-Daley LA, Standaert DG, West AB. Xu E, et al. Among authors: sokratian a. Mol Neurodegener. 2022 Jan 10;17(1):7. doi: 10.1186/s13024-021-00509-5. Mol Neurodegener. 2022. PMID: 35012605 Free PMC article.
12 results