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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1927 1
1948 2
1950 1
1951 1
1952 5
1953 4
1954 5
1955 5
1956 4
1957 7
1958 6
1959 4
1960 5
1961 6
1962 15
1963 22
1964 31
1965 30
1966 37
1967 50
1968 53
1969 51
1970 58
1971 90
1972 118
1973 124
1974 112
1975 159
1976 183
1977 172
1978 203
1979 202
1980 251
1981 238
1982 222
1983 253
1984 247
1985 234
1986 286
1987 230
1988 287
1989 311
1990 286
1991 286
1992 290
1993 291
1994 295
1995 332
1996 304
1997 289
1998 298
1999 290
2000 286
2001 299
2002 301
2003 282
2004 289
2005 279
2006 285
2007 325
2008 307
2009 315
2010 349
2011 354
2012 366
2013 381
2014 385
2015 339
2016 346
2017 333
2018 367
2019 342
2020 389
2021 139
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13,512 results
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Page 1
Spermidine inhibits vascular calcification in chronic kidney disease through modulation of SIRT1 signaling pathway.
Liu X, Chen A, Liang Q, Yang X, Dong Q, Fu M, Wang S, Li Y, Ye Y, Lan Z, Chen Y, Ou JS, Yang P, Lu L, Yan J. Liu X, et al. Aging Cell. 2021 May 9:e13377. doi: 10.1111/acel.13377. Online ahead of print. Aging Cell. 2021. PMID: 33969611
Additionally, western blot analysis revealed that spermidine treatment inhibited osteogenic differentiation of rat and human VSMCs. ...Both pharmacological inhibition of SIRT1 by SIRT1 inhibitor EX527 and knockdown of SIRT1 by siRNA markedly blocked the inhibitory effect o …
Additionally, western blot analysis revealed that spermidine treatment inhibited osteogenic differentiation of rat and human VSMCs. . …
Changes in biogenic amines, biochemical and microbial attributes of three spotted crab (Portunus sanguinolentus) during iced and refrigerated storage.
Laly SJ, Anupama TK, Ashok Kumar K, Sankar TV, Ninan G. Laly SJ, et al. J Food Sci Technol. 2021 Jun;58(6):2197-2205. doi: 10.1007/s13197-020-04730-w. Epub 2020 Aug 20. J Food Sci Technol. 2021. PMID: 33967317
Biochemical, microbial and sensory characters along with formation of biogenic amines of whole crabs stored under iced and refrigerated condition was evaluated. Cadaverine, putrescine and spermidine were the major amines formed during spoilage and a strong correlation betw …
Biochemical, microbial and sensory characters along with formation of biogenic amines of whole crabs stored under iced and refrigerated cond …
Metabolomics in Glaucoma: A Systematic Review.
Wang Y, Hou XW, Liang G, Pan CW. Wang Y, et al. Invest Ophthalmol Vis Sci. 2021 May 3;62(6):9. doi: 10.1167/iovs.62.6.9. Invest Ophthalmol Vis Sci. 2021. PMID: 33956051
Seventeen metabolites related to OAG were repeatedly identified, including seven amino acids (arginine, glycine, alanine, lysine, methionine, phenylalanine, tyrosine), two phosphatidylcholine (PC aa C34:2, PC aa C36:4), three complements (acetylcarnitine, propionylcarnitine, buty …
Seventeen metabolites related to OAG were repeatedly identified, including seven amino acids (arginine, glycine, alanine, lysine, methionine …
Bioaccessibility of phenolic acids in Canadian hulless barley varieties.
Drawbridge PC, Apea-Bah F, Silveira Hornung P, Beta T. Drawbridge PC, et al. Food Chem. 2021 Apr 20;358:129905. doi: 10.1016/j.foodchem.2021.129905. Online ahead of print. Food Chem. 2021. PMID: 33940288
A hydroxycinnamic acid amide not reported before in boiled barley, N(1), N(8)- dicaffeoyl spermidine, was identified in free phenolic extracts with relatively high abundance compared to the phenolic acids. ...
A hydroxycinnamic acid amide not reported before in boiled barley, N(1), N(8)- dicaffeoyl spermidine, was identified in free phenolic …
The Vibrio cholerae SpeG Spermidine/Spermine N-Acetyltransferase Allosteric Loop and beta6-beta7 Structural Elements Are Critical for Kinetic Activity.
Le VTB, Tsimbalyuk S, Lim EQ, Solis A, Gawat D, Boeck P, Lim EQ, Renolo R, Forwood JK, Kuhn ML. Le VTB, et al. Front Mol Biosci. 2021 Apr 13;8:645768. doi: 10.3389/fmolb.2021.645768. eCollection 2021. Front Mol Biosci. 2021. PMID: 33928120 Free PMC article.
Their intracellular concentrations are tightly regulated by polyamine transport systems and biosynthetic and catabolic pathways. Spermidine/spermine N-acetyltransferases (SSATs) are catabolic enzymes that acetylate polyamines and are critical for maintaining intracellular …
Their intracellular concentrations are tightly regulated by polyamine transport systems and biosynthetic and catabolic pathways. Spermidi
Spermidine alkaloid and glycosidic constituents of Vietnamese Homalium cochinchinensis.
Addo EM, Ren Y, Anaya-Eugenio GD, Ninh TN, Rakotondraibe HL, de Blanco EJC, Soejarto DD, Kinghorn AD. Addo EM, et al. Phytochem Lett. 2021 Jun;43:154-162. doi: 10.1016/j.phytol.2021.04.002. Epub 2021 Apr 15. Phytochem Lett. 2021. PMID: 33927787
Phytochemical investigation of the aerial parts of Homalium cochinchinensis led to the isolation of secondary metabolites belonging to the spermidine alkaloid, glycoside, depsidone and phenol classes. Of the eleven secondary metabolites isolated in this study, two sperm
Phytochemical investigation of the aerial parts of Homalium cochinchinensis led to the isolation of secondary metabolites belonging to the …
Putrescine Depletion Affects Arabidopsis Root Meristem Size by Modulating Auxin and Cytokinin Signaling and ROS Accumulation.
Hashem AM, Moore S, Chen S, Hu C, Zhao Q, Elesawi IE, Feng Y, Topping JF, Liu J, Lindsey K, Chen C. Hashem AM, et al. Int J Mol Sci. 2021 Apr 15;22(8):4094. doi: 10.3390/ijms22084094. Int J Mol Sci. 2021. PMID: 33920993 Free PMC article.
Decreasing putrescine resulted in an interesting inverted-U-trend in primary root growth and a similar trend in MZ size, and differential changes in putrescine (Put), spermidine (Spd), and combined spermine (Spm) plus thermospermine (Tspm) levels. ...
Decreasing putrescine resulted in an interesting inverted-U-trend in primary root growth and a similar trend in MZ size, and differential ch …
Potential Use of Vacuum Impregnation and High-Pressure Homogenization to Obtain Functional Products from Lulo Fruit (Solanum quitoense Lam.).
Hinestroza-Córdoba LI, Barrera C, Seguí L, Betoret N. Hinestroza-Córdoba LI, et al. Foods. 2021 Apr 9;10(4):817. doi: 10.3390/foods10040817. Foods. 2021. PMID: 33918871 Free PMC article.
The aim of this study was to determine physicochemical and antioxidant properties (antioxidant capacity, total phenols, flavonoids and spermidine content, and polyphenolic compounds profile by liquid chromatography-mass spectrometry (LC-MS)) of the lulo fruit and its juice …
The aim of this study was to determine physicochemical and antioxidant properties (antioxidant capacity, total phenols, flavonoids and sp
Metformin Inhibits the Urea Cycle and Reduces Putrescine Generation in Colorectal Cancer Cell Lines.
Zhang T, Hu L, Tang JF, Xu H, Tian K, Wu MN, Huang SY, Du YM, Zhou P, Lu RJ, He S, Xu JM, Si JJ, Li J, Chen DL, Ran JH. Zhang T, et al. Molecules. 2021 Apr 1;26(7):1990. doi: 10.3390/molecules26071990. Molecules. 2021. PMID: 33915902 Free PMC article.
Cytoplasmic ornithine, the intermediate product of the urea cycle, is a specific substrate for ornithine decarboxylase (ODC, also known as ODC1) for the production of putrescine and is required for tumor growth. Polyamines (spermidine, spermine, and their precursor putresc …
Cytoplasmic ornithine, the intermediate product of the urea cycle, is a specific substrate for ornithine decarboxylase (ODC, also known as O …
Increased polyamine levels and maintenance of γ-aminobutyric acid (Gaba) homeostasis in the gills is indicative of osmotic plasticity in killifish.
Munley KM, Liu D, Galvez F. Munley KM, et al. Comp Biochem Physiol A Mol Integr Physiol. 2021 Apr 27;257:110969. doi: 10.1016/j.cbpa.2021.110969. Online ahead of print. Comp Biochem Physiol A Mol Integr Physiol. 2021. PMID: 33915271
Fish acclimated to 32 ppt or 12 ppt water were transferred to fresh water, and concentrations of glutamate (Glu), Gaba, and the polyamines putrescine (Put), spermidine (Spd), and spermine (Spm) were measured in the gills using high-performance liquid chromatography. ...
Fish acclimated to 32 ppt or 12 ppt water were transferred to fresh water, and concentrations of glutamate (Glu), Gaba, and the polyamines p …
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