Spermidine in health and disease.
Science. 2018.
PMID: 29371440
Review.
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Spermidine in health and disease.
Science. 2018 Jan 26;359(6374):eaan2788. doi: 10.1126/science.aan2788.
Science. 2018.
PMID: 29371440
Review.
One such agent, the natural polyamine spermidine, has prominent cardioprotective and neuroprotective effects and stimulates anticancer immunosurveillance in rodent models. Moreover, dietary polyamine uptake correlates with reduced cardiovascular and cancer-related mortalit …
One such agent, the natural polyamine spermidine, has prominent cardioprotective and neuroprotective effects and stimulates anticance …
The mysterious polyamines, the enigmatic Barr body, and lupus: comment on the article by Kim et al.
Lupus. 2018 May;27(6):877-879. doi: 10.1177/0961203318757929. Epub 2018 Feb 14.
Lupus. 2018.
PMID: 29444615
Polyamine involvement in many cellular processes and their unique characteristics (high charge, length, flexibility, and ubiquity) give polyamines importance in health and disease. In this editorial, I describe a scenario, the "X chromosome-nucleolus nexus" h …
Polyamine involvement in many cellular processes and their unique characteristics (high charge, length, flexibility, and ubiquity) give poly …
Polyamine metabolites and conjugates in man and higher animals: a review of the literature.
Physiol Chem Phys. 1980;12(5):389-400.
Physiol Chem Phys. 1980.
PMID: 7010391
Review.
The current state of knowledge of the metabolic fate of the di- and polyamines putrescine, spermidine, and spermine is reviewed. Acetylated, oxidized, and protein-bound polyamines are found to be widely distributed in man and animals. The importance of understanding the ro …
The current state of knowledge of the metabolic fate of the di- and polyamines putrescine, spermidine, and spermine is reviewed. Acet …
B-type natriuretic peptide protects cardiomyocytes at reperfusion via mitochondrial calcium uniporter.
Biomed Pharmacother. 2010 Mar;64(3):170-6. doi: 10.1016/j.biopha.2009.09.024. Epub 2010 Jan 9.
Biomed Pharmacother. 2010.
PMID: 20149572
B-type natriuretic peptide (BNP) is a regulatory autacoid in the mammalian myocardium, whose functions play significant roles in health and disease. Previous work has identified that BNP protect myocardium through mitochondrial pathway-dependent mechanism aga …
B-type natriuretic peptide (BNP) is a regulatory autacoid in the mammalian myocardium, whose functions play significant roles in h …
Major depression model induced by repeated and intermittent lipopolysaccharide administration: Long-lasting behavioral, neuroimmune and neuroprogressive alterations.
J Psychiatr Res. 2018 Dec;107:57-67. doi: 10.1016/j.jpsychires.2018.10.003. Epub 2018 Oct 5.
J Psychiatr Res. 2018.
PMID: 30326340
Six weeks after the last LPS-exposure, we assessed behavioral despair and anhedonia, microglial activation, alterations in tryptophan, 5-HT, kynurenine, quinolinic acid (QUIN) levels and spermidine/spermine N1-acetyltransferase (SAT1) expression in the hippocampus, both wi …
Six weeks after the last LPS-exposure, we assessed behavioral despair and anhedonia, microglial activation, alterations in tryptophan, 5-HT, …
N(8)-acetylspermidine as a potential plasma biomarker for Snyder-Robinson syndrome identified by clinical metabolomics.
J Inherit Metab Dis. 2016 Jan;39(1):131-7. doi: 10.1007/s10545-015-9876-y. Epub 2015 Jul 15.
J Inherit Metab Dis. 2016.
PMID: 26174906
Free article.
Clinical metabolomics has emerged as a powerful tool to study human metabolism in health and disease. Comparative statistical analysis of untargeted metabolic profiles can reveal perturbations of metabolite levels in diseases and thus has the potential …
Clinical metabolomics has emerged as a powerful tool to study human metabolism in health and disease. Comparative stati …
The involvement of the polyamines binding sites at the NMDA receptor in creatine-induced spatial learning enhancement.
Behav Brain Res. 2008 Feb 11;187(1):200-4. doi: 10.1016/j.bbr.2007.09.004. Epub 2007 Sep 14.
Behav Brain Res. 2008.
PMID: 17950476
Achievements made over the last years have highlighted the important role of creatine in health and disease. However, studies of its effect on cognition function have been limited. ...The involvement of polyamine binding site at NMDA receptor in creatine-indu …
Achievements made over the last years have highlighted the important role of creatine in health and disease. However, s …
Clinical usefulness of an enzymatic determination of total urinary polyamines, excluding cadaverine.
Clin Chem. 1988 Nov;34(11):2271-4.
Clin Chem. 1988.
PMID: 3180422
In one widely used enzymatic method for urinary polyamines, the total concentrations of four polyamines--putrescine, spermidine, spermine, and cadaverine--are determined. We report here a simple enzymatic method for measuring the total concentrations of urinary polyamines …
In one widely used enzymatic method for urinary polyamines, the total concentrations of four polyamines--putrescine, spermidine, sper …
Polyamines and polyamine complexes: analytical comments.
Physiol Chem Phys. 1980;12(5):473-80.
Physiol Chem Phys. 1980.
PMID: 7208641
Different methods of sample preparation for determination of di- and polyamines (putrescine, spermidine, spermine) and their conjugates in serum, plasma, and urine are discussed. ...Additional polyamines might be bound to proteins and released by hydrolysis of the crude sa …
Different methods of sample preparation for determination of di- and polyamines (putrescine, spermidine, spermine) and their conjugat …
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