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1998 1
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Page 1
Current Insights on the Photoprotective Mechanism of the Macular Carotenoids, Lutein and Zeaxanthin: Safety, Efficacy and Bio-Delivery.
Kumar P, Banik SP, Ohia SE, Moriyama H, Chakraborty S, Wang CK, Song YS, Goel A, Bagchi M, Bagchi D. Kumar P, et al. J Am Nutr Assoc. 2024 Aug;43(6):505-518. doi: 10.1080/27697061.2024.2319090. Epub 2024 Feb 23. J Am Nutr Assoc. 2024. PMID: 38393321 Review.
Ocular health has emerged as one of the major issues of global health concern with a decline in quality of life in an aging population, in particular and rise in the number of associated morbidities and mortalities. ...Apart from the benefits imparted to ocular health, lut …
Ocular health has emerged as one of the major issues of global health concern with a decline in quality of life in an aging populatio …
Reversing the deleterious effects of aging on neuronal communication and behavior: beneficial properties of fruit polyphenolic compounds.
Joseph JA, Shukitt-Hale B, Casadesus G. Joseph JA, et al. Am J Clin Nutr. 2005 Jan;81(1 Suppl):313S-316S. doi: 10.1093/ajcn/81.1.313S. Am J Clin Nutr. 2005. PMID: 15640496 Free article. Review.
Despite elegant research involving molecular biology studies and determination of the genetic mechanisms of aging, practical information on how to forestall or reverse the deleterious effects of aging may be years away. ...Research from our laboratory suggested that …
Despite elegant research involving molecular biology studies and determination of the genetic mechanisms of aging, practical informat …
Fruit polyphenolics and brain aging: nutritional interventions targeting age-related neuronal and behavioral deficits.
Galli RL, Shukitt-Hale B, Youdim KA, Joseph JA. Galli RL, et al. Ann N Y Acad Sci. 2002 Apr;959:128-32. doi: 10.1111/j.1749-6632.2002.tb02089.x. Ann N Y Acad Sci. 2002. PMID: 11976192 Review.
Nutritional interventions, in this case, increasing dietary intake of fruits and vegetables, can retard and even reverse age-related declines in brain function and in cognitive and motor performance in rats. Our lab has shown that as Fischer 344 rats age their brains are i …
Nutritional interventions, in this case, increasing dietary intake of fruits and vegetables, can retard and even reverse age-related decline …
Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation.
Joseph JA, Shukitt-Hale B, Denisova NA, Bielinski D, Martin A, McEwen JJ, Bickford PC. Joseph JA, et al. J Neurosci. 1999 Sep 15;19(18):8114-21. doi: 10.1523/JNEUROSCI.19-18-08114.1999. J Neurosci. 1999. PMID: 10479711 Free PMC article.
Our previous study had shown that rats given dietary supplements of fruit and vegetable extracts with high antioxidant activity for 8 months beginning at 6 months of age retarded age-related declines in neuronal and cognitive function. The present study showed that such su …
Our previous study had shown that rats given dietary supplements of fruit and vegetable extracts with high antioxidant activity for 8 months …
Neuroprotective Effect of α-Lipoic Acid against Aβ25-35-Induced Damage in BV2 Cells.
Pei X, Hu F, Hu Z, Luo F, Li X, Xing S, Sun L, Long D. Pei X, et al. Molecules. 2023 Jan 24;28(3):1168. doi: 10.3390/molecules28031168. Molecules. 2023. PMID: 36770835 Free PMC article.
The prevalence of Alzheimer's disease (AD) is significantly increasing due to the aging world population, and the currently available drug treatments cannot cure or even slow its progression. alpha-lipoic acid (LA) is a biological factor widely found in spinach and …
The prevalence of Alzheimer's disease (AD) is significantly increasing due to the aging world population, and the currently available …
Long-term dietary strawberry, spinach, or vitamin E supplementation retards the onset of age-related neuronal signal-transduction and cognitive behavioral deficits.
Joseph JA, Shukitt-Hale B, Denisova NA, Prior RL, Cao G, Martin A, Taglialatela G, Bickford PC. Joseph JA, et al. J Neurosci. 1998 Oct 1;18(19):8047-55. doi: 10.1523/JNEUROSCI.18-19-08047.1998. J Neurosci. 1998. PMID: 9742171 Free PMC article.
Recent research has indicated that increased vulnerability to oxidative stress may be the major factor involved in CNS functional declines in aging and age-related neurodegenerative diseases, and that antioxidants, e.g., vitamin E, may ameliorate or prevent these declines. …
Recent research has indicated that increased vulnerability to oxidative stress may be the major factor involved in CNS functional declines i …
Effect of fruits, vegetables, or vitamin E--rich diet on vitamins E and C distribution in peripheral and brain tissues: implications for brain function.
Martin A, Prior R, Shukitt-Hale B, Cao G, Joseph JA. Martin A, et al. J Gerontol A Biol Sci Med Sci. 2000 Mar;55(3):B144-51. doi: 10.1093/gerona/55.3.b144. J Gerontol A Biol Sci Med Sci. 2000. PMID: 10795718
Age-related neurodegenerative conditions are the principal cause of declining cognitive and motor function during aging. Evidence support that fruits and vegetables containing generous amounts of antioxidant nutrients are important for neurological function. ...In a …
Age-related neurodegenerative conditions are the principal cause of declining cognitive and motor function during aging. Evide …
Effect of a Strawberry and Spinach Dietary Supplement on Spatial Learning in Early and Late Middle-Aged Female Rats.
Millin PM, Rickert GM. Millin PM, et al. Antioxidants (Basel). 2018 Dec 20;8(1):1. doi: 10.3390/antiox8010001. Antioxidants (Basel). 2018. PMID: 30577447 Free PMC article.
Thus, our model showed that a high antioxidant diet of relatively short duration mitigated the mild cognitive decline that was seen in control animals during the developmental period of late middle-age. The current results offer support for the promising role of dietary an …
Thus, our model showed that a high antioxidant diet of relatively short duration mitigated the mild cognitive decline that was seen i …
Eighteen-month-old Fischer 344 rats fed a spinach-enriched diet show improved delay classical eyeblink conditioning and reduced expression of tumor necrosis factor alpha (TNFalpha ) and TNFbeta in the cerebellum.
Cartford MC, Gemma C, Bickford PC. Cartford MC, et al. J Neurosci. 2002 Jul 15;22(14):5813-6. doi: 10.1523/JNEUROSCI.22-14-05813.2002. J Neurosci. 2002. PMID: 12122042 Free PMC article.
Diets high in antioxidant properties are known to reverse some deficits in neuronal and cognitive function that occur in aging animals. Antioxidants are also known to reduce levels of proinflammatory factors in the CNS. ...Cerebelli from older animals on the spin …
Diets high in antioxidant properties are known to reverse some deficits in neuronal and cognitive function that occur in aging …