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21,935 results

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Page 1
Spontaneously hypertensive rat as a model of vascular brain disorder: microanatomy, neurochemistry and behavior.
Tayebati SK, Tomassoni D, Amenta F. Tayebati SK, et al. J Neurol Sci. 2012 Nov 15;322(1-2):241-9. doi: 10.1016/j.jns.2012.05.047. Epub 2012 Jun 21. J Neurol Sci. 2012. PMID: 22726353 Review.
These findings suggest that arterial hypertension is a main cause of vascular brain disorder (VBD). Spontaneously hypertensive rat (SHR) is the rat strain most extensively investigated and used for assessing hypertensive brain damage and …
These findings suggest that arterial hypertension is a main cause of vascular brain disorder (VBD). Spontaneously hypertensive …
Spontaneously hypertensive rat (SHR) as an animal model for ADHD: a short overview.
Meneses A, Perez-Garcia G, Ponce-Lopez T, Tellez R, Gallegos-Cari A, Castillo C. Meneses A, et al. Rev Neurosci. 2011;22(3):365-71. doi: 10.1515/RNS.2011.024. Epub 2011 May 13. Rev Neurosci. 2011. PMID: 21591908 Review.
Some ADHD dysfunctional domains are reflected in the spontaneously hypertensive rat (SHR). Because ADHD, drugs and animal models are eliciting a growing interest, hence the aim of this work is to present a brief overview with a focus on the SHR …
Some ADHD dysfunctional domains are reflected in the spontaneously hypertensive rat (SHR). Because ADHD, drugs a …
The spontaneously hypertensive rat model of ADHD--the importance of selecting the appropriate reference strain.
Sagvolden T, Johansen EB, Wøien G, Walaas SI, Storm-Mathisen J, Bergersen LH, Hvalby O, Jensen V, Aase H, Russell VA, Killeen PR, Dasbanerjee T, Middleton FA, Faraone SV. Sagvolden T, et al. Neuropharmacology. 2009 Dec;57(7-8):619-26. doi: 10.1016/j.neuropharm.2009.08.004. Epub 2009 Aug 19. Neuropharmacology. 2009. PMID: 19698722 Free PMC article. Review.
Based on a wider range of criteria - behavioral, genetic and neurobiological - the spontaneously hypertensive rat (SHR) obtained from Charles River, Germany (SHR/NCrl) at present constitutes the best validated animal model of ADHD combined subty …
Based on a wider range of criteria - behavioral, genetic and neurobiological - the spontaneously hypertensive rat (S …
Testicular morphology in spontaneously hypertensive rat model: oxidant status and stereological implications.
Azu OO. Azu OO. Andrologia. 2015 Mar;47(2):123-37. doi: 10.1111/and.12233. Epub 2014 Jan 28. Andrologia. 2015. PMID: 24471984 Review.
The investigation of these factors occurring under hypertensive states using the spontaneously hypertensive rat (SHR) as an experimental model has attracted substantial attention in recent past. This review examines the relationships and potenti …
The investigation of these factors occurring under hypertensive states using the spontaneously hypertensive rat …
Genetics of hypertension: an assessment of progress in the spontaneously hypertensive rat.
Doris PA. Doris PA. Physiol Genomics. 2017 Nov 1;49(11):601-617. doi: 10.1152/physiolgenomics.00065.2017. Epub 2017 Sep 15. Physiol Genomics. 2017. PMID: 28916635 Free PMC article. Review.
The application of gene mapping methods to uncover the genetic basis of hypertension in the inbred spontaneously hypertensive rat (SHR) began over 25 yr ago. This animal provides a useful model of genetic high blood pressure, and some of its fea …
The application of gene mapping methods to uncover the genetic basis of hypertension in the inbred spontaneously hypertensi …
The stroke-prone spontaneously hypertensive rat: how good is it as a model for cerebrovascular diseases?
Nabika T, Cui Z, Masuda J. Nabika T, et al. Cell Mol Neurobiol. 2004 Oct;24(5):639-46. doi: 10.1023/b:cemn.0000036402.79129.2f. Cell Mol Neurobiol. 2004. PMID: 15485135 Free PMC article. Review.
Cerebrovascular diseases (CVDs) in humans are a mixture of diseases with different etiologies. 2. Although the stroke-prone spontaneously hypertensive rat (SHRSP) cannot represent all types of CVDs, it is probably a good genetic model for particular types suc …
Cerebrovascular diseases (CVDs) in humans are a mixture of diseases with different etiologies. 2. Although the stroke-prone spontaneously …
Drug reinforcement in a rat model of attention deficit/hyperactivity disorder--the Spontaneously Hypertensive Rat (SHR).
Vendruscolo LF, Izídio GS, Takahashi RN. Vendruscolo LF, et al. Curr Drug Abuse Rev. 2009 May;2(2):177-83. doi: 10.2174/1874473710902020177. Curr Drug Abuse Rev. 2009. PMID: 19630747 Review.
Therefore, animal models to study this kind of psychiatric comorbidity are needed. The Spontaneously Hypertensive Rat (SHR) strain shows neurochemical and behavioral characteristics which make it a suitable model of ADHD. Compared with their normotensi …
Therefore, animal models to study this kind of psychiatric comorbidity are needed. The Spontaneously Hypertensive Rat ( …
Dopamine hypofunction possibly results from a defect in glutamate-stimulated release of dopamine in the nucleus accumbens shell of a rat model for attention deficit hyperactivity disorder--the spontaneously hypertensive rat.
Russell VA. Russell VA. Neurosci Biobehav Rev. 2003 Nov;27(7):671-82. doi: 10.1016/j.neubiorev.2003.08.010. Neurosci Biobehav Rev. 2003. PMID: 14624811 Review.
Dopamine hypofunction possibly results from a defect in glutamate-stimulated release of dopamine in the nucleus accumbens shell of a rat model for attention deficit hyperactivity disorder-the spontaneously hypertensive rat. ...Disturbances in glutamate …
Dopamine hypofunction possibly results from a defect in glutamate-stimulated release of dopamine in the nucleus accumbens shell of a rat …
Antihypertensive drugs in the stroke-prone spontaneously hypertensive rat.
Richer C, Vacher E, Fornes P, Giudicelli JF. Richer C, et al. Clin Exp Hypertens. 1997 Jul-Aug;19(5-6):925-36. doi: 10.3109/10641969709083196. Clin Exp Hypertens. 1997. PMID: 9247765 Free article. Review.
The stroke-prone spontaneously hypertensive rat (SHR-SP) is an experimental model that has been widely used to investigate the potential preventive effects vs stroke and mortality of numerous antihypertensive agents. ...
The stroke-prone spontaneously hypertensive rat (SHR-SP) is an experimental model that has been widely used to i …
Conplastic strains for identification of retrograde effects of mitochondrial dna variation on cardiometabolic traits in the spontaneously hypertensive rat.
Pravenec M, Šilhavý J, Mlejnek P, Šimáková M, Mráček T, Pecinová A, Tauchmannová K, Hütl M, Malínská H, Kazdová L, Neckář J, Kolář F, Žurmanová J, Novotný J, Houštěk J. Pravenec M, et al. Physiol Res. 2021 Dec 30;70(Suppl4):S471-S484. doi: 10.33549/physiolres.934740. Physiol Res. 2021. PMID: 35199537 Free PMC article. Review.
To analyze the relationship between mtDNA variants and cardiometabolic traits, we derived a set of rat conplastic strains (SHR-mtBN, SHR-mtF344 and SHR-mtLEW), harboring all major mtDNA haplotypes present in common inbred strains on the nuclear …
To analyze the relationship between mtDNA variants and cardiometabolic traits, we derived a set of rat conplastic strains (SHR …
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