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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1977 2
1978 1
1981 4
1982 1
1983 3
1984 8
1985 4
1986 6
1987 5
1988 5
1989 11
1990 22
1991 19
1992 26
1993 26
1994 35
1995 36
1996 41
1997 27
1998 32
1999 39
2000 55
2001 62
2002 67
2003 98
2004 91
2005 126
2006 141
2007 175
2008 226
2009 191
2010 251
2011 283
2012 269
2013 322
2014 346
2015 355
2016 368
2017 398
2018 450
2019 437
2020 420
2021 205
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5,034 results
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Page 1
Statin drugs to reduce breast cancer recurrence and mortality.
Beckwitt CH, Brufsky A, Oltvai ZN, Wells A. Beckwitt CH, et al. Breast Cancer Res. 2018 Nov 20;20(1):144. doi: 10.1186/s13058-018-1066-z. Breast Cancer Res. 2018. PMID: 30458856 Free PMC article. Review.
This has engendered studies as to their influence on concomitant diseases, including cancers. In this context, statin use has been correlated, variably, with a decrease in deaths from breast cancer. ...Second, the basic and clinical research studies that inve …
This has engendered studies as to their influence on concomitant diseases, including cancers. In this context, statin use has …
Impact of statin use on cancer recurrence and mortality in breast cancer: A systematic review and meta-analysis.
Manthravadi S, Shrestha A, Madhusudhana S. Manthravadi S, et al. Int J Cancer. 2016 Sep 15;139(6):1281-8. doi: 10.1002/ijc.30185. Epub 2016 May 31. Int J Cancer. 2016. PMID: 27176735 Free article. Review.
They inhibit the enzyme "HMG CoA reductase" and the expression of this enzyme in cancer cells has been implicated as a favorable prognostic factor in patients with breast cancer. ...Statin users also had improved overall survival and cancer
They inhibit the enzyme "HMG CoA reductase" and the expression of this enzyme in cancer cells has been implicated as a …
Statin Use and Risk of Pancreatic Cancer: An Updated Meta-analysis of 26 Studies.
Zhang Y, Liang M, Sun C, Qu G, Shi T, Min M, Wu Y, Sun Y. Zhang Y, et al. Pancreas. 2019 Feb;48(2):142-150. doi: 10.1097/MPA.0000000000001226. Pancreas. 2019. PMID: 30640225 Review.
In subgroup analyses, nonsignificant association was detected between long-term statin use and the risk of pancreatic cancer (RR, 0.98; 95% CI, 0.86-1.11; P = 0.718; I(2) = 0.0%). Meanwhile, there was nonsignificant association between the use of lipophilic stati
In subgroup analyses, nonsignificant association was detected between long-term statin use and the risk of pancreatic cancer ( …
Molecular Determinants of Statin-sensitivity in Cancer.
Fatehi Hassanabad A, Wong JVS. Fatehi Hassanabad A, et al. Am J Clin Oncol. 2020 Mar;43(3):160-162. doi: 10.1097/COC.0000000000000655. Am J Clin Oncol. 2020. PMID: 31842115 No abstract available.
Statin use and reduced cancer-related mortality.
Nielsen SF, Nordestgaard BG, Bojesen SE. Nielsen SF, et al. N Engl J Med. 2012 Nov 8;367(19):1792-802. doi: 10.1056/NEJMoa1201735. N Engl J Med. 2012. PMID: 23134381 Free article.
The reduced cancer-related mortality among statin users as compared with those who had never used statins was observed for each of 13 cancer types. CONCLUSIONS: Statin use in patients with cancer is associated with reduced cancer-r …
The reduced cancer-related mortality among statin users as compared with those who had never used statins was observed …
Statins use and cancer: an update.
Zaleska M, Mozenska O, Bil J. Zaleska M, et al. Future Oncol. 2018 Jun;14(15):1497-1509. doi: 10.2217/fon-2017-0543. Epub 2018 May 3. Future Oncol. 2018. PMID: 29722274 Review.
After initial concerns regarding the association of statins with increased incidences of cancer and elevated cancer-related mortality, there are now plenty of data on the antitumor, cytostatic and cytotoxic effectiveness of this class of drugs. Here, we prese …
After initial concerns regarding the association of statins with increased incidences of cancer and elevated cancer-rel …
Statin use and breast cancer survival - a Swedish nationwide study.
Borgquist S, Broberg P, Tojjar J, Olsson H. Borgquist S, et al. BMC Cancer. 2019 Jan 11;19(1):54. doi: 10.1186/s12885-018-5263-z. BMC Cancer. 2019. PMID: 30634941 Free PMC article.
BACKGROUND: A sizeable body of evidence suggests that statins can cease breast cancer progression and prevent breast cancer recurrence. ...These disparities should be further investigated to pave the way for future randomized clinical trials investigating the …
BACKGROUND: A sizeable body of evidence suggests that statins can cease breast cancer progression and prevent breast cancer
The Impact of Statin Therapy on the Survival of Patients with Gastrointestinal Cancer.
Gachpazan M, Kashani H, Khazaei M, Hassanian SM, Rezayi M, Asgharzadeh F, Ghayour-Mobarhan M, Ferns GA, Avan A. Gachpazan M, et al. Curr Drug Targets. 2019;20(7):738-747. doi: 10.2174/1389450120666181211165449. Curr Drug Targets. 2019. PMID: 30539694 Review.
Statins are 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors that may play an important role in the evolution of cancers, due to their effects on cancer cell metabolism. ...It would be useful for these trials to incorp
Statins are 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors that may play an important role
Statins: a role in breast cancer therapy?
Borgquist S, Bjarnadottir O, Kimbung S, Ahern TP. Borgquist S, et al. J Intern Med. 2018 Oct;284(4):346-357. doi: 10.1111/joim.12806. Epub 2018 Jul 9. J Intern Med. 2018. PMID: 29923256 Free PMC article. Review.
Statins halt hepatic cholesterol biosynthesis by inhibiting the rate-limiting enzyme in the mevalonate pathway, hydroxymethylglutaryl-coenzyme A reductase (HMGCR). ...The number of clinical trials assessing the putative clinical benefit of statins in b
Statins halt hepatic cholesterol biosynthesis by inhibiting the rate-limiting enzyme in the mevalonate pathway, hydroxymethylgluta
Exploring association between statin use and breast cancer risk: an updated meta-analysis.
Islam MM, Yang HC, Nguyen PA, Poly TN, Huang CW, Kekade S, Khalfan AM, Debnath T, Li YJ, Abdul SS. Islam MM, et al. Arch Gynecol Obstet. 2017 Dec;296(6):1043-1053. doi: 10.1007/s00404-017-4533-3. Epub 2017 Sep 22. Arch Gynecol Obstet. 2017. PMID: 28940025 Review.
However, preclinical studies suggested that statins may influence mammary cancer growth, but the clinical evidence is still inconsistent. ...However, we also stratified by region, the duration of statin therapy, methodological design, statin properties …
However, preclinical studies suggested that statins may influence mammary cancer growth, but the clinical evidence is still in …
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