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1974 1
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1983 25
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2013 1320
2014 1515
2015 1660
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31,184 results

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Page 1
Statins-From Fungi to Pharmacy.
Sadowska A, Osiński P, Roztocka A, Kaczmarz-Chojnacka K, Zapora E, Sawicka D, Car H. Sadowska A, et al. Int J Mol Sci. 2023 Dec 29;25(1):466. doi: 10.3390/ijms25010466. Int J Mol Sci. 2023. PMID: 38203637 Free PMC article. Review.
Statins are classified into natural, semi-synthetic derivatives of natural statins, and synthetic ones. Synthetic statins differ from natural statins in their structural composition, with the only common feature being the HMG-CoA-like moiety responsibl …
Statins are classified into natural, semi-synthetic derivatives of natural statins, and synthetic ones. Synthetic statins …
Statins and muscle pain.
Pergolizzi JV Jr, Coluzzi F, Colucci RD, Olsson H, LeQuang JA, Al-Saadi J, Magnusson P. Pergolizzi JV Jr, et al. Expert Rev Clin Pharmacol. 2020 Mar;13(3):299-310. doi: 10.1080/17512433.2020.1734451. Epub 2020 Feb 27. Expert Rev Clin Pharmacol. 2020. PMID: 32089020 Free article. Review.
However, muscle symptoms are often reported from patients on statins. Muscle symptoms are frequently reported as adverse events associated with statin therapy.Areas covered: In the present narrative review, statin-associated muscle pain is discussed. ...There …
However, muscle symptoms are often reported from patients on statins. Muscle symptoms are frequently reported as adverse events assoc …
Statins in Children, an Update.
Fiorentino R, Chiarelli F. Fiorentino R, et al. Int J Mol Sci. 2023 Jan 10;24(2):1366. doi: 10.3390/ijms24021366. Int J Mol Sci. 2023. PMID: 36674877 Free PMC article. Review.
Before initiating statins, it is imperative for clinical practitioners to consult patients and families and, as with any new medication therapy, to monitor patients taking statins. ...It is therefore important that clinicians become familiar with statins....
Before initiating statins, it is imperative for clinical practitioners to consult patients and families and, as with any new medicati …
Pleiotropic Effects of Statins on the Cardiovascular System.
Oesterle A, Laufs U, Liao JK. Oesterle A, et al. Circ Res. 2017 Jan 6;120(1):229-243. doi: 10.1161/CIRCRESAHA.116.308537. Circ Res. 2017. PMID: 28057795 Free PMC article. Review.
Statins may exert cardiovascular protective effects that are independent of LDL-cholesterol lowering called pleiotropic effects. ...This review examines some of the currently proposed molecular mechanisms for statin pleiotropy and discusses whether they could have a …
Statins may exert cardiovascular protective effects that are independent of LDL-cholesterol lowering called pleiotropic effects. ...T …
Rhabdomyolysis and statins: A pharmacovigilance comparative study between statins.
Montastruc JL. Montastruc JL. Br J Clin Pharmacol. 2023 Aug;89(8):2636-2638. doi: 10.1111/bcp.15757. Epub 2023 May 8. Br J Clin Pharmacol. 2023. PMID: 37186323 Free article.
Rhabdomyolysis is a serious adverse drug reaction of statins. There are few studies comparing the risk of rhabdomyolysis between the different statins. ...Among 10 657 reports with rhabdomyolysis with statins, simvastatin was the highest risk statin in …
Rhabdomyolysis is a serious adverse drug reaction of statins. There are few studies comparing the risk of rhabdomyolysis between the …
Statins Effects on Blood Clotting: A Review.
Siniscalchi C, Basaglia M, Riva M, Meschi M, Meschi T, Castaldo G, Di Micco P. Siniscalchi C, et al. Cells. 2023 Nov 27;12(23):2719. doi: 10.3390/cells12232719. Cells. 2023. PMID: 38067146 Free PMC article. Review.
Statins are powerful lipid-lowering drugs that inhibit cholesterol biosynthesis via downregulation of hydroxymethylglutaryl coenzyme-A reductase, which are largely used in patients with or at risk of cardiovascular disease. Available data on thromboembolic disease i …
Statins are powerful lipid-lowering drugs that inhibit cholesterol biosynthesis via downregulation of hydroxymethylglutaryl coenzyme- …
Statins as anti-tumor agents: A paradigm for repurposed drugs.
Tripathi S, Gupta E, Galande S. Tripathi S, et al. Cancer Rep (Hoboken). 2024 May;7(5):e2078. doi: 10.1002/cnr2.2078. Cancer Rep (Hoboken). 2024. PMID: 38711272 Free PMC article. Review.
BACKGROUND: Statins, frequently prescribed medications, work by inhibiting the rate-limiting enzyme HMG-CoA reductase (HMGCR) in the mevalonate pathway to reduce cholesterol levels. Due to their multifaceted benefits, statins are being adapted for use as cost …
BACKGROUND: Statins, frequently prescribed medications, work by inhibiting the rate-limiting enzyme HMG-CoA reductase (HMGCR) …
Ticagrelor and Statins: Dangerous Liaisons?
Rocca B, Bigagli E, Cerbai E. Rocca B, et al. Cardiovasc Drugs Ther. 2024 Dec;38(6):1103-1109. doi: 10.1007/s10557-024-07624-7. Epub 2024 Sep 30. Cardiovasc Drugs Ther. 2024. PMID: 39348077 Free PMC article. Review.
Rhabdomyolysis is a very rare but severe adverse event, which is specific for statins which can be triggered by DDIs that increase statin's concentrations through blockade of their biotransformation and/or elimination. ...While the clinical impact of this DDI …
Rhabdomyolysis is a very rare but severe adverse event, which is specific for statins which can be triggered by DDIs that increase …
Statins for the Primary Prevention of Anthracycline Cardiotoxicity: A Comprehensive Review.
Bhasin V, Vakilpour A, Scherrer-Crosbie M. Bhasin V, et al. Curr Oncol Rep. 2024 Oct;26(10):1197-1204. doi: 10.1007/s11912-024-01579-6. Epub 2024 Jul 13. Curr Oncol Rep. 2024. PMID: 39002055 Free PMC article. Review.
Statins have been associated with a lower risk of cardiac dysfunction in cancer patients receiving anthracyclines. Further investigation with larger randomized control trials and longer follow-up periods are needed to better evaluate the long-term role of statin the …
Statins have been associated with a lower risk of cardiac dysfunction in cancer patients receiving anthracyclines. Further investigat …
Statins use and the prognosis of colorectal cancer: a meta-analysis.
Li L, Cui N, Hao T, Zou J, Jiao W, Yi K, Yu W. Li L, et al. Clin Res Hepatol Gastroenterol. 2021 Sep;45(5):101588. doi: 10.1016/j.clinre.2020.101588. Epub 2021 Mar 1. Clin Res Hepatol Gastroenterol. 2021. PMID: 33662632 Free article.
The multivariate hazard ratios (HRs) and their 95% confidence intervals (CI) were computed to explore associations between statins use and overall mortality or cancer-specific mortality of CRC. RESULTS: The study included 5 retrospective case-control studies (including 475 …
The multivariate hazard ratios (HRs) and their 95% confidence intervals (CI) were computed to explore associations between statins us …
31,184 results
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