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Year Number of Results
1974 1
1975 1
1976 4
1977 7
1978 4
1979 7
1980 19
1981 17
1982 14
1983 25
1984 15
1985 24
1986 21
1987 18
1988 23
1989 38
1990 59
1991 52
1992 55
1993 74
1994 59
1995 76
1996 51
1997 77
1998 81
1999 124
2000 149
2001 198
2002 221
2003 337
2004 371
2005 472
2006 556
2007 622
2008 830
2009 917
2010 1074
2011 1111
2012 1215
2013 1326
2014 1510
2015 1661
2016 1741
2017 1716
2018 1699
2019 1768
2020 2011
2021 2248
2022 2271
2023 2079
2024 1863
2025 717

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Page 1
Statins: a repurposed drug to fight cancer.
Jiang W, Hu JW, He XR, Jin WL, He XY. Jiang W, et al. J Exp Clin Cancer Res. 2021 Jul 24;40(1):241. doi: 10.1186/s13046-021-02041-2. J Exp Clin Cancer Res. 2021. PMID: 34303383 Free PMC article. Review.
As competitive HMG-CoA reductase (HMGCR) inhibitors, statins not only reduce cholesterol and improve cardiovascular risk, but also exhibit pleiotropic effects that are independent of their lipid-lowering effects. ...A large number of clinical and epidemiologi …
As competitive HMG-CoA reductase (HMGCR) inhibitors, statins not only reduce cholesterol and improve cardiovascular ris …
Statins-From Fungi to Pharmacy.
Sadowska A, Osiński P, Roztocka A, Kaczmarz-Chojnacka K, Zapora E, Sawicka D, Car H. Sadowska A, et al. Int J Mol Sci. 2023 Dec 29;25(1):466. doi: 10.3390/ijms25010466. Int J Mol Sci. 2023. PMID: 38203637 Free PMC article. Review.
Statins are classified into natural, semi-synthetic derivatives of natural statins, and synthetic ones. Synthetic statins differ from natural statins in their structural composition, with the only common feature being the HMG-CoA-like moiety responsibl …
Statins are classified into natural, semi-synthetic derivatives of natural statins, and synthetic ones. Synthetic statins …
Treatment with Statins in Elderly Patients.
Horodinschi RN, Stanescu AMA, Bratu OG, Pantea Stoian A, Radavoi DG, Diaconu CC. Horodinschi RN, et al. Medicina (Kaunas). 2019 Oct 30;55(11):721. doi: 10.3390/medicina55110721. Medicina (Kaunas). 2019. PMID: 31671689 Free PMC article. Review.
Secondary prevention after a stroke or myocardial infarction includes mandatory a statin, to diminish the risk of a recurrent cardiovascular event. The possible side effects of statin therapy are diabetes mellitus, myopathy, and rhabdomyolysis, hepatotoxicity. The s …
Secondary prevention after a stroke or myocardial infarction includes mandatory a statin, to diminish the risk of a recurrent cardiov …
Statins and muscle pain.
Pergolizzi JV Jr, Coluzzi F, Colucci RD, Olsson H, LeQuang JA, Al-Saadi J, Magnusson P. Pergolizzi JV Jr, et al. Expert Rev Clin Pharmacol. 2020 Mar;13(3):299-310. doi: 10.1080/17512433.2020.1734451. Epub 2020 Feb 27. Expert Rev Clin Pharmacol. 2020. PMID: 32089020 Free article. Review.
However, muscle symptoms are often reported from patients on statins. Muscle symptoms are frequently reported as adverse events associated with statin therapy.Areas covered: In the present narrative review, statin-associated muscle pain is discussed. ...There …
However, muscle symptoms are often reported from patients on statins. Muscle symptoms are frequently reported as adverse events assoc …
Pleiotropic Effects of Statins on the Cardiovascular System.
Oesterle A, Laufs U, Liao JK. Oesterle A, et al. Circ Res. 2017 Jan 6;120(1):229-243. doi: 10.1161/CIRCRESAHA.116.308537. Circ Res. 2017. PMID: 28057795 Free PMC article. Review.
Statins may exert cardiovascular protective effects that are independent of LDL-cholesterol lowering called pleiotropic effects. ...This review examines some of the currently proposed molecular mechanisms for statin pleiotropy and discusses whether they could have a …
Statins may exert cardiovascular protective effects that are independent of LDL-cholesterol lowering called pleiotropic effects. ...T …
Statins Effects on Blood Clotting: A Review.
Siniscalchi C, Basaglia M, Riva M, Meschi M, Meschi T, Castaldo G, Di Micco P. Siniscalchi C, et al. Cells. 2023 Nov 27;12(23):2719. doi: 10.3390/cells12232719. Cells. 2023. PMID: 38067146 Free PMC article. Review.
Statins are powerful lipid-lowering drugs that inhibit cholesterol biosynthesis via downregulation of hydroxymethylglutaryl coenzyme-A reductase, which are largely used in patients with or at risk of cardiovascular disease. Available data on thromboembolic disease i …
Statins are powerful lipid-lowering drugs that inhibit cholesterol biosynthesis via downregulation of hydroxymethylglutaryl coenzyme- …
Comparison of statins for secondary prevention in patients with ischemic stroke or transient ischemic attack: a systematic review and network meta-analysis.
Tramacere I, Boncoraglio GB, Banzi R, Del Giovane C, Kwag KH, Squizzato A, Moja L. Tramacere I, et al. BMC Med. 2019 Mar 26;17(1):67. doi: 10.1186/s12916-019-1298-5. BMC Med. 2019. PMID: 30914063 Free PMC article.
BACKGROUND: Statins may prevent recurrent ischemic events after ischemic stroke. Determining which statin to use remains controversial. ...We performed pairwise meta-analyses and trial sequential analyses (TSA) to compare statins versus placebo/no statin …
BACKGROUND: Statins may prevent recurrent ischemic events after ischemic stroke. Determining which statin to use remains contr …
Statins and the Brain: More than Lipid Lowering Agents?
Fracassi A, Marangoni M, Rosso P, Pallottini V, Fioramonti M, Siteni S, Segatto M. Fracassi A, et al. Curr Neuropharmacol. 2019;17(1):59-83. doi: 10.2174/1570159X15666170703101816. Curr Neuropharmacol. 2019. PMID: 28676012 Free PMC article. Review.
BACKGROUND: Statins represent a class of medications widely prescribed to efficiently treat dyslipidemia. ...OBJECTIVE: The purpose of this review is to summarize and examine the current knowledge about pharmacokinetic and pharmacodynamic properties of statins in th …
BACKGROUND: Statins represent a class of medications widely prescribed to efficiently treat dyslipidemia. ...OBJECTIVE: The purpose o …
Statins for the Primary Prevention of Anthracycline Cardiotoxicity: A Comprehensive Review.
Bhasin V, Vakilpour A, Scherrer-Crosbie M. Bhasin V, et al. Curr Oncol Rep. 2024 Oct;26(10):1197-1204. doi: 10.1007/s11912-024-01579-6. Epub 2024 Jul 13. Curr Oncol Rep. 2024. PMID: 39002055 Free PMC article. Review.
Statins have been associated with a lower risk of cardiac dysfunction in cancer patients receiving anthracyclines. Further investigation with larger randomized control trials and longer follow-up periods are needed to better evaluate the long-term role of statin the …
Statins have been associated with a lower risk of cardiac dysfunction in cancer patients receiving anthracyclines. Further investigat …
Statins in Mitigating Anticancer Treatment-Related Cardiovascular Disease.
Jiang R, Lou L, Shi W, Chen Y, Fu Z, Liu S, Sok T, Li Z, Zhang X, Yang J. Jiang R, et al. Int J Mol Sci. 2024 Sep 22;25(18):10177. doi: 10.3390/ijms251810177. Int J Mol Sci. 2024. PMID: 39337662 Free PMC article. Review.
There is prospective clinical evidence confirming the protective role of statins in chemotherapy-induced cardiotoxicity. Numerous preclinical studies have demonstrated that statins can ameliorate heart and endothelial damage caused by radiotherapy, although clinical …
There is prospective clinical evidence confirming the protective role of statins in chemotherapy-induced cardiotoxicity. Numerous pre …
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