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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
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1987 5
1988 5
1989 11
1990 22
1991 19
1992 26
1993 26
1994 35
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1998 32
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2000 56
2001 62
2002 67
2003 98
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2005 126
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2007 175
2008 225
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2011 283
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2024 402
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6,513 results

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Page 1
Statins: a repurposed drug to fight cancer.
Jiang W, Hu JW, He XR, Jin WL, He XY. Jiang W, et al. J Exp Clin Cancer Res. 2021 Jul 24;40(1):241. doi: 10.1186/s13046-021-02041-2. J Exp Clin Cancer Res. 2021. PMID: 34303383 Free PMC article. Review.
As competitive HMG-CoA reductase (HMGCR) inhibitors, statins not only reduce cholesterol and improve cardiovascular risk, but also exhibit pleiotropic effects that are independent of their lipid-lowering effects. Among them, the anti-cancer properties …
As competitive HMG-CoA reductase (HMGCR) inhibitors, statins not only reduce cholesterol and improve cardiovascular ris …
Microbiota-derived tryptophan catabolites mediate the chemopreventive effects of statins on colorectal cancer.
Han JX, Tao ZH, Wang JL, Zhang L, Yu CY, Kang ZR, Xie Y, Li J, Lu S, Cui Y, Xu J, Zhao E, Wang M, Chen J, Wang Z, Liu Q, Chen HM, Su W, Zou TH, Zhou CB, Hong J, Chen H, Xiong H, Chen YX, Fang JY. Han JX, et al. Nat Microbiol. 2023 May;8(5):919-933. doi: 10.1038/s41564-023-01363-5. Epub 2023 Apr 17. Nat Microbiol. 2023. PMID: 37069401
Epidemiological studies have indicated an association between statin use and reduced incidence of colorectal cancer (CRC), and work in preclinical models has demonstrated a potential chemopreventive effect. ...Together, our study provides insights into an anti-ca …
Epidemiological studies have indicated an association between statin use and reduced incidence of colorectal cancer (CRC), and …
Statins and cancer.
Vallianou NG, Kostantinou A, Kougias M, Kazazis C. Vallianou NG, et al. Anticancer Agents Med Chem. 2014 Jun;14(5):706-12. doi: 10.2174/1871520613666131129105035. Anticancer Agents Med Chem. 2014. PMID: 24295174 Review.
Statins have pleiotropic properties and might exert an effect even in the field of cancer. ...As compared to statin non-users, patients using statins prior to cancer diagnosis were 15% less likely to die from any cause or cancer specifica …
Statins have pleiotropic properties and might exert an effect even in the field of cancer. ...As compared to statin non …
Statins and prostate cancer-hype or hope? The biological perspective.
Longo J, Freedland SJ, Penn LZ, Hamilton RJ. Longo J, et al. Prostate Cancer Prostatic Dis. 2022 Apr;25(4):650-656. doi: 10.1038/s41391-022-00557-y. Epub 2022 Jun 29. Prostate Cancer Prostatic Dis. 2022. PMID: 35768578 Review.
Growing evidence suggests that men prescribed a statin for cholesterol control have a lower risk of advanced prostate cancer (PCa) and improved treatment outcomes; however, the mechanism by which statins elicit their anti-neoplastic effects is not well unders …
Growing evidence suggests that men prescribed a statin for cholesterol control have a lower risk of advanced prostate cancer ( …
Statins as Repurposed Drugs in Gynecological Cancer: A Review.
Wang KH, Liu CH, Ding DC. Wang KH, et al. Int J Mol Sci. 2022 Nov 11;23(22):13937. doi: 10.3390/ijms232213937. Int J Mol Sci. 2022. PMID: 36430409 Free PMC article. Review.
Thus, statins have great potential to be repurposed in oncology. Hence, we review the meta-analysis, cohort, and case-control studies of statins in gynecological cancers, and elucidate how statins regulate cell proliferation, apoptosis, tumor growth, a …
Thus, statins have great potential to be repurposed in oncology. Hence, we review the meta-analysis, cohort, and case-control studies …
Statins for Cardiac and Vascular Protection During and After Cancer Therapy.
Heiston EM, Hundley WG. Heiston EM, et al. Curr Oncol Rep. 2022 May;24(5):555-561. doi: 10.1007/s11912-022-01212-4. Epub 2022 Feb 24. Curr Oncol Rep. 2022. PMID: 35199294 Free PMC article. Review.
This manuscript presents data accumulated to date regarding cardiovascular outcomes relating to the administration of 3-hydroxy-3-methylglutarylcoenzyme-A reductase inhibitor (or statin) therapy in individuals receiving potentially cardiotoxic cancer treatmen …
This manuscript presents data accumulated to date regarding cardiovascular outcomes relating to the administration of 3-hydroxy-3-methylglut …
Statins and Cancer Prevention-Association Does Not Mean Causation.
Das S, Freedland SJ. Das S, et al. Cancer Prev Res (Phila). 2023 Jan 4;16(1):1-3. doi: 10.1158/1940-6207.CAPR-22-0420. Cancer Prev Res (Phila). 2023. PMID: 36597731 Free PMC article.
Given the key role of cholesterol in cancer, statins may therefore have anticancer activities. However, clinical studies investigating the association between statin usage and cancer development have been few and inconsistent. ...This editorial analyze …
Given the key role of cholesterol in cancer, statins may therefore have anticancer activities. However, clinical studies inves …
Statins use and cancer: an update.
Zaleska M, Mozenska O, Bil J. Zaleska M, et al. Future Oncol. 2018 Jun;14(15):1497-1509. doi: 10.2217/fon-2017-0543. Epub 2018 May 3. Future Oncol. 2018. PMID: 29722274 Review.
After initial concerns regarding the association of statins with increased incidences of cancer and elevated cancer-related mortality, there are now plenty of data on the antitumor, cytostatic and cytotoxic effectiveness of this class of drugs. Here, we prese …
After initial concerns regarding the association of statins with increased incidences of cancer and elevated cancer-rel …
Statins as Potential Therapeutics for Esophageal Cancer.
Fatehi Hassanabad A, Wong JVS. Fatehi Hassanabad A, et al. J Gastrointest Cancer. 2021 Sep;52(3):833-838. doi: 10.1007/s12029-021-00648-4. Epub 2021 May 31. J Gastrointest Cancer. 2021. PMID: 34056697 Review.
There is a growing body of literature that has shown the anticancer properties of statins in the setting of various malignancies. Herein, we summarize and assimilate the current evidence pertaining to the potential anti-esophageal cancer benefits of statins. …
There is a growing body of literature that has shown the anticancer properties of statins in the setting of various malignancies. Her …
Attempts to use statins in cancer therapy: An update.
Matusewicz L, Czogalla A, Sikorski AF. Matusewicz L, et al. Tumour Biol. 2020 Jul;42(7):1010428320941760. doi: 10.1177/1010428320941760. Tumour Biol. 2020. PMID: 32662332 Free article. Review.
Although it could be speculated that almost everything has been said concerning the use of statins in cancer therapy, statins as anticancer drugs have both committed supporters and opponents, for whom the dispute about the legitimacy of statin use in …
Although it could be speculated that almost everything has been said concerning the use of statins in cancer therapy, stati …
6,513 results

Searches related to "statins cancer"