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Year Number of Results
1994 1
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2001 4
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2004 6
2005 5
2006 9
2007 4
2008 13
2009 16
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2011 31
2012 33
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981 results

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Page 1
Extracellular vesicles from adipose tissue-derived stem cells alleviate osteoporosis through osteoprotegerin and miR-21-5p.
Lee KS, Lee J, Kim HK, Yeom SH, Woo CH, Jung YJ, Yun YE, Park SY, Han J, Kim E, Sul JH, Jung JM, Park JH, Choi JS, Cho YW, Jo DG. Lee KS, et al. J Extracell Vesicles. 2021 Oct;10(12):e12152. doi: 10.1002/jev2.12152. J Extracell Vesicles. 2021. PMID: 34596354 Free PMC article.
Osteoporosis is one of the most common skeletal disorders caused by the imbalance between bone formation and resorption, resulting in quantitative loss of bone tissue. ...Additionally, small RNA sequencing data were analysed to identify miRNA candidates related to anti- …
Osteoporosis is one of the most common skeletal disorders caused by the imbalance between bone formation and resorption, resulting in …
WTAP-mediated m(6)A modification modulates bone marrow mesenchymal stem cells differentiation potential and osteoporosis.
You Y, Liu J, Zhang L, Li X, Sun Z, Dai Z, Ma J, Jiao G, Chen Y. You Y, et al. Cell Death Dis. 2023 Jan 17;14(1):33. doi: 10.1038/s41419-023-05565-x. Cell Death Dis. 2023. PMID: 36650131 Free PMC article.
An imbalance in the differentiation potential of bone marrow mesenchymal stem cells (BMSCs) is an important pathogenic mechanism underlying osteoporosis (OP). N6-methyladenosine (m(6)A) is the most common post-transcriptional modification in eukaryotic cells. ...Our result …
An imbalance in the differentiation potential of bone marrow mesenchymal stem cells (BMSCs) is an important pathogenic mechanism underlying …
Mettl3-mediated m(6)A RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis.
Wu Y, Xie L, Wang M, Xiong Q, Guo Y, Liang Y, Li J, Sheng R, Deng P, Wang Y, Zheng R, Jiang Y, Ye L, Chen Q, Zhou X, Lin S, Yuan Q. Wu Y, et al. Nat Commun. 2018 Nov 14;9(1):4772. doi: 10.1038/s41467-018-06898-4. Nat Commun. 2018. PMID: 30429466 Free PMC article.
Here we show that conditional knockout of the m(6)A methyltransferase Mettl3 in bone marrow mesenchymal stem cells (MSCs) induces pathological features of osteoporosis in mice. Mettl3 loss-of-function results in impaired bone formation, incompetent osteogenic differentiati …
Here we show that conditional knockout of the m(6)A methyltransferase Mettl3 in bone marrow mesenchymal stem cells (MSCs) induces pathologic …
Genistein mitigates senescence of bone marrow mesenchymal stem cells via ERRalpha-mediated mitochondrial biogenesis and mitophagy in ovariectomized rats.
Li M, Yu Y, Xue K, Li J, Son G, Wang J, Qian W, Wang S, Zheng J, Yang C, Ge J. Li M, et al. Redox Biol. 2023 May;61:102649. doi: 10.1016/j.redox.2023.102649. Epub 2023 Feb 27. Redox Biol. 2023. PMID: 36871183 Free PMC article.
Senescence of bone marrow mesenchymal stem cells (BMMSCs) induced by chronic oxidative stress is an important factor contributes to the postmenopausal osteoporosis (PMOP). Mitochondrial quality control takes a pivotal role in regulating oxidative stress and cell sen …
Senescence of bone marrow mesenchymal stem cells (BMMSCs) induced by chronic oxidative stress is an important factor contributes to the p …
Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?
Chen Q, Shou P, Zheng C, Jiang M, Cao G, Yang Q, Cao J, Xie N, Velletri T, Zhang X, Xu C, Zhang L, Yang H, Hou J, Wang Y, Shi Y. Chen Q, et al. Cell Death Differ. 2016 Jul;23(7):1128-39. doi: 10.1038/cdd.2015.168. Epub 2016 Feb 12. Cell Death Differ. 2016. PMID: 26868907 Free PMC article. Review.
The dysregulation of the adipo-osteogenic balance has been linked to several pathophysiologic processes, such as aging, obesity, osteopenia, osteopetrosis, and osteoporosis. Thus, the regulation of MSC differentiation has increasingly attracted great attention in recent ye …
The dysregulation of the adipo-osteogenic balance has been linked to several pathophysiologic processes, such as aging, obesity, osteopenia, …
Exosomes derived from bone marrow mesenchymal stem cells improve osteoporosis through promoting osteoblast proliferation via MAPK pathway.
Zhao P, Xiao L, Peng J, Qian YQ, Huang CC. Zhao P, et al. Eur Rev Med Pharmacol Sci. 2018 Jun;22(12):3962-3970. doi: 10.26355/eurrev_201806_15280. Eur Rev Med Pharmacol Sci. 2018. PMID: 29949171 Free article.
OBJECTIVE: Osteoporosis is the most common bone metabolic disease. Exosome exerts a crucial role in the development of multiple diseases. The aim of the study was to investigate the role of exosome derived from bone marrow mesenchymal stem cells (MSCs) in osteoporosis …
OBJECTIVE: Osteoporosis is the most common bone metabolic disease. Exosome exerts a crucial role in the development of multiple disea …
Melatonin Inhibits the Ferroptosis Pathway in Rat Bone Marrow Mesenchymal Stem Cells by Activating the PI3K/AKT/mTOR Signaling Axis to Attenuate Steroid-Induced Osteoporosis.
Li M, Yang N, Hao L, Zhou W, Li L, Liu L, Yang F, Xu L, Yao G, Zhu C, Xu W, Fang S. Li M, et al. Oxid Med Cell Longev. 2022 Aug 18;2022:8223737. doi: 10.1155/2022/8223737. eCollection 2022. Oxid Med Cell Longev. 2022. PMID: 36035224 Free PMC article.
Steroid-induced osteoporosis (SIOP) is a form of secondary osteoporosis, but its specific mechanism remains unclear. ...
Steroid-induced osteoporosis (SIOP) is a form of secondary osteoporosis, but its specific mechanism remains unclear. ...
Synergistic Effect of Magneto-Mechanical Bioengineered Stem Cells and Magnetic Field to Alleviate Osteoporosis.
Yu C, Yang W, Yang L, Ye L, Sun R, Gu T, Ying X, Wang M, Tang R, Fan S, Yao S. Yu C, et al. ACS Appl Mater Interfaces. 2023 Apr 26;15(16):19976-19988. doi: 10.1021/acsami.3c01139. Epub 2023 Apr 14. ACS Appl Mater Interfaces. 2023. PMID: 37058439
In vivo experiments confirm that the functional MSCs and guided MF could effectively alleviate postmenopausal osteoporosis, and the bone mass of the treated osteoporotic bones by using the bioengineered cells for 6 weeks is nearly identical to that of the healthy on …
In vivo experiments confirm that the functional MSCs and guided MF could effectively alleviate postmenopausal osteoporosis, an …
Osteoporosis treatment by mesenchymal stromal/stem cells and their exosomes: Emphasis on signaling pathways and mechanisms.
Rudiansyah M, El-Sehrawy AA, Ahmad I, Terefe EM, Abdelbasset WK, Bokov DO, Salazar A, Rizaev JA, Muthanna FMS, Shalaby MN. Rudiansyah M, et al. Life Sci. 2022 Oct 1;306:120717. doi: 10.1016/j.lfs.2022.120717. Epub 2022 Jul 2. Life Sci. 2022. PMID: 35792178 Review.
Osteoporosis is the loss of bone density, which is one of the main problems in developed and developing countries and is more common in the elderly. ...In this article, we attempted to review new studies in which MSCs and their exosomes were used to treat osteoporosis …
Osteoporosis is the loss of bone density, which is one of the main problems in developed and developing countries and is more common …
PTH and stem cells.
Ohishi M, Schipani E. Ohishi M, et al. J Endocrinol Invest. 2011 Jul-Aug;34(7):552-6. doi: 10.3275/7620. Epub 2011 Mar 22. J Endocrinol Invest. 2011. PMID: 21427529 Review.
PTH is the first bone anabolic agent approved by US Food and Drug Administration for the treatment of osteoporosis. Recent studies have suggested that PTH treatment may affect the number of hematopoietic stem cells in the bone marrow and their mobilization into the bloodst …
PTH is the first bone anabolic agent approved by US Food and Drug Administration for the treatment of osteoporosis. Recent studies ha …
981 results