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Year Number of Results
1825 1
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1844 1
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1887 3
1888 1
1893 1
1898 1
1904 1
1907 2
1908 1
1911 1
1914 1
1917 1
1918 1
1919 1
1921 1
1923 2
1925 2
1927 1
1931 1
1932 1
1936 1
1945 3
1946 10
1947 12
1948 10
1949 14
1950 11
1951 7
1952 6
1953 9
1954 17
1955 4
1956 7
1957 15
1958 7
1959 17
1960 19
1961 14
1962 11
1963 13
1964 22
1965 15
1966 19
1967 38
1968 24
1969 19
1970 31
1971 45
1972 30
1973 34
1974 40
1975 123
1976 191
1977 140
1978 163
1979 173
1980 189
1981 237
1982 232
1983 271
1984 343
1985 291
1986 319
1987 339
1988 399
1989 473
1990 499
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1992 562
1993 674
1994 672
1995 698
1996 727
1997 820
1998 839
1999 913
2000 1029
2001 1124
2002 1248
2003 1274
2004 1670
2005 1896
2006 2141
2007 2314
2008 2584
2009 2851
2010 3173
2011 3808
2012 4197
2013 4866
2014 5218
2015 5524
2016 5758
2017 6100
2018 6413
2019 6676
2020 7481
2021 8408
2022 8237
2023 7986
2024 8500
2025 9914
2026 1410

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118,126 results

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Page 1
Matrix Stiffness Contributes to Cancer Progression by Regulating Transcription Factors.
Ishihara S, Haga H. Ishihara S, et al. Cancers (Basel). 2022 Feb 18;14(4):1049. doi: 10.3390/cancers14041049. Cancers (Basel). 2022. PMID: 35205794 Free PMC article. Review.
Matrix stiffness is critical for the progression of various types of cancers. In solid cancers such as mammary and pancreatic cancers, tumors often contain abnormally stiff tissues, mainly caused by stiff extracellular matrices due to accumulation, contractio …
Matrix stiffness is critical for the progression of various types of cancers. In solid cancers such as mammary and pancreatic cancers …
The Stiffness-Sensitive Transcriptome of Human Tendon Stromal Cells.
Hussien AA, Niederoest B, Bollhalder M, Goedecke N, Snedeker JG. Hussien AA, et al. Adv Healthc Mater. 2023 Mar;12(7):e2101216. doi: 10.1002/adhm.202101216. Epub 2023 Jan 20. Adv Healthc Mater. 2023. PMID: 36509005 Free PMC article.
Extracellular matrix stiffness is a major regulator of cellular states. Stiffness-sensing investigations are typically performed using cells that have acquired "mechanical memory" through prolonged conditioning in rigid environments, e.g., tissue culture plastic (TC …
Extracellular matrix stiffness is a major regulator of cellular states. Stiffness-sensing investigations are typically perform …
Stiff Guidewires in Endourology: What Is Stiffness?
Kolvatzis M, Sierra A, Corrales M, Traxer O. Kolvatzis M, et al. J Endourol. 2022 Nov;36(11):1475-1482. doi: 10.1089/end.2022.0165. Epub 2022 Sep 27. J Endourol. 2022. PMID: 35801659 Review.
Introduction: The aim of this study is to perform a literature review of stiff guidewires used in urology and to investigate if there is an official definition for stiffness (shaft rigidity) of wires. ...We found no concrete data regarding their stiffness on …
Introduction: The aim of this study is to perform a literature review of stiff guidewires used in urology and to investigate if there …
Multiplanar Stiffness of Commercial Carbon Composite Ankle-Foot Orthoses.
Shuman BR, Russell Esposito E. Shuman BR, et al. J Biomech Eng. 2022 Jan 1;144(1):011004. doi: 10.1115/1.4051845. J Biomech Eng. 2022. PMID: 34286822 Free PMC article.
AFOs with a lateral strut demonstrated frontal plane stiffnesses up to 0.71 N.m/deg of eversion while those with a medial strut demonstrated frontal plane stiffnesses up to 0.53 N.m/deg of inversion. Transverse plane stiffnesses were less than 0.30 N.m/deg of …
AFOs with a lateral strut demonstrated frontal plane stiffnesses up to 0.71 N.m/deg of eversion while those with a medial strut demon …
Matrix stiffness regulates osteoclast fate through integrin-dependent mechanotransduction.
Wang X, Ji L, Wang J, Liu C. Wang X, et al. Bioact Mater. 2023 Mar 30;27:138-153. doi: 10.1016/j.bioactmat.2023.03.014. eCollection 2023 Sep. Bioact Mater. 2023. PMID: 37064801 Free PMC article.
Here, a hydrogel was created to imitate the physiological bone microenvironment, with stiffnesses ranging from 2.43kPa to 68.2kPa. The impact of matrix stiffness on osteoclast behaviors was thoroughly investigated. ...Our works provide an innovative approach for fin …
Here, a hydrogel was created to imitate the physiological bone microenvironment, with stiffnesses ranging from 2.43kPa to 68.2kPa. Th …
Matrix stiffness-induced platelet activation determines immunomodulation of macrophages.
Hang R, Wang Z, Wang H, Zhang Y, Zhao Y, Bai L, Yao X. Hang R, et al. Biomater Adv. 2023 May;148:213356. doi: 10.1016/j.bioadv.2023.213356. Epub 2023 Feb 23. Biomater Adv. 2023. PMID: 36848742
The results showed that the matrix stiffness was positively related with activation degree of platelets. However, the extracts of platelets incubated on middle-stiff matrix polarized macrophages to pro-healing M2 phenotype when compared with that on soft and stif …
The results showed that the matrix stiffness was positively related with activation degree of platelets. However, the extracts of pla …
Stiffness-dependent dynamic effect of inflammation on keratocyte phenotype and differentiation.
Chen J, Mo Q, Sheng R, Long Q, Chen Z, Liu C, Zhang A, Luo Y, Liu J, Zhang W. Chen J, et al. Biomed Mater. 2023 Apr 27;18(4). doi: 10.1088/1748-605X/accda9. Biomed Mater. 2023. PMID: 37068490
Soft and stiff substrates were prepared based on polydimethylsiloxane. HTK and stem cells were cultured on these substrates to evaluate the effects of stiffness. ...In addition, macrophages were cultured on soft and stiff substrates to evaluate the effect of …
Soft and stiff substrates were prepared based on polydimethylsiloxane. HTK and stem cells were cultured on these substrates to evalua …
The impact of ankle-foot orthosis stiffness on gait: A systematic literature review.
Totah D, Menon M, Jones-Hershinow C, Barton K, Gates DH. Totah D, et al. Gait Posture. 2019 Mar;69:101-111. doi: 10.1016/j.gaitpost.2019.01.020. Epub 2019 Jan 15. Gait Posture. 2019. PMID: 30708092
These design parameters affect the ankle stiffness of the AFO. RESEARCH QUESTION: The aim of this review was to investigate the impact of AFO stiffness on walking mechanics. ...There were no generalizable trends for the impact of stiffness on user preference. …
These design parameters affect the ankle stiffness of the AFO. RESEARCH QUESTION: The aim of this review was to investigate the impac …
Substrate stiffness-dependent regulatory volume decrease and calcium signaling in chondrocytes.
Zhang M, Wu X, Du G, Chen W, Zhang Q. Zhang M, et al. Acta Biochim Biophys Sin (Shanghai). 2022 Jan 25;54(1):113-125. doi: 10.3724/abbs.2021008. Acta Biochim Biophys Sin (Shanghai). 2022. PMID: 35130619 Free PMC article.
This study aims to investigate the effects of substrate stiffness on the chondrocyte RVD and calcium signaling by recapitulating the physiologically relevant substrate stiffness. ...Our work also suggests that the TRPV4 channel is involved in the chondrocyte sensing …
This study aims to investigate the effects of substrate stiffness on the chondrocyte RVD and calcium signaling by recapitulating the …
A Pneumatic Particle-Blocking Variable-Stiffness Actuator.
Peng H, Wang X, Geng D, Xu W. Peng H, et al. Sensors (Basel). 2023 Dec 14;23(24):9817. doi: 10.3390/s23249817. Sensors (Basel). 2023. PMID: 38139663 Free PMC article.
In order to improve the stiffness of flexible robots, this paper proposes a variable-stiffness elastic actuator. ...The anti-compressive stiffness and lateral stiffness increase nonlinearly as air pressure increases, being 3 and 121 times greater at 0. …
In order to improve the stiffness of flexible robots, this paper proposes a variable-stiffness elastic actuator. ...The anti-c …
118,126 results
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