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Year Number of Results
1955 1
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1966 1
1967 1
1968 2
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1971 2
1972 2
1973 1
1974 2
1975 6
1976 13
1977 17
1978 10
1979 8
1980 15
1981 21
1982 13
1983 21
1984 18
1985 30
1986 22
1987 29
1988 36
1989 48
1990 31
1991 44
1992 51
1993 65
1994 68
1995 62
1996 76
1997 63
1998 83
1999 76
2000 62
2001 90
2002 101
2003 95
2004 100
2005 99
2006 107
2007 118
2008 99
2009 108
2010 117
2011 151
2012 162
2013 196
2014 218
2015 244
2016 234
2017 225
2018 290
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2023 375
2024 301

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5,217 results

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Page 1
Strand Displacement Strategies for Biosensor Applications.
Dai Y, Furst A, Liu CC. Dai Y, et al. Trends Biotechnol. 2019 Dec;37(12):1367-1382. doi: 10.1016/j.tibtech.2019.10.001. Epub 2019 Nov 1. Trends Biotechnol. 2019. PMID: 31679827 Review.
Differences in sequence complementarity between multiple DNA strands can lead to the strand displacement reaction (SDR). SDRs have been regularly applied in synthetic biology, drug delivery, and, importantly, biosensing. ...
Differences in sequence complementarity between multiple DNA strands can lead to the strand displacement reaction (SDR) …
Principles and Applications of Nucleic Acid Strand Displacement Reactions.
Simmel FC, Yurke B, Singh HR. Simmel FC, et al. Chem Rev. 2019 May 22;119(10):6326-6369. doi: 10.1021/acs.chemrev.8b00580. Epub 2019 Feb 4. Chem Rev. 2019. PMID: 30714375 Review.
Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the study and application of nucleic acid strand-displacement reactions. Strand-displacement reactions generally proceed by three-way or four-way branch migration and initi …
Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the study and application of nucleic acid strand-d …
Genetic switches based on nucleic acid strand displacement.
Wang T, Hellmer H, Simmel FC. Wang T, et al. Curr Opin Biotechnol. 2023 Feb;79:102867. doi: 10.1016/j.copbio.2022.102867. Epub 2022 Dec 17. Curr Opin Biotechnol. 2023. PMID: 36535150 Review.
Toehold-mediated strand displacement (TMSD) is an isothermal switching process that enables the sequence-programmable and reversible conversion of DNA or RNA strands between single- and double-stranded conformations or other secondary structures. ...
Toehold-mediated strand displacement (TMSD) is an isothermal switching process that enables the sequence-programmable and reve …
Loop-mediated isothermal amplification of DNA.
Notomi T, Okayama H, Masubuchi H, Yonekawa T, Watanabe K, Amino N, Hase T. Notomi T, et al. Nucleic Acids Res. 2000 Jun 15;28(12):E63. doi: 10.1093/nar/28.12.e63. Nucleic Acids Res. 2000. PMID: 10871386 Free PMC article.
An inner primer containing sequences of the sense and antisense strands of the target DNA initiates LAMP. The following strand displacement DNA synthesis primed by an outer primer releases a single-stranded DNA. ...In subsequent LAMP cycling one inner …
An inner primer containing sequences of the sense and antisense strands of the target DNA initiates LAMP. The following strand …
Pathways and assays for DNA double-strand break repair by homologous recombination.
Li J, Sun H, Huang Y, Wang Y, Liu Y, Chen X. Li J, et al. Acta Biochim Biophys Sin (Shanghai). 2019 Sep 6;51(9):879-889. doi: 10.1093/abbs/gmz076. Acta Biochim Biophys Sin (Shanghai). 2019. PMID: 31294447 Free article. Review.
The HR pathway is initiated by processing of the 5'-end of DSBs to generate 3'-end single-strand DNA (ssDNA). Furthermore, the intermediate is channeled to one of the HR sub-pathways, including: (i) double Holliday junction (dHJ) pathway, (ii) synthesis-dependent strand …
The HR pathway is initiated by processing of the 5'-end of DSBs to generate 3'-end single-strand DNA (ssDNA). Furthermore, the interm …
Directing Uphill Strand Displacement with an Engineered Superhelicase.
Hall-Thomsen H, Small S, Gavrilov M, Ha T, Schulman R, Moerman PG. Hall-Thomsen H, et al. ACS Synth Biol. 2023 Nov 17;12(11):3424-3432. doi: 10.1021/acssynbio.3c00452. Epub 2023 Oct 16. ACS Synth Biol. 2023. PMID: 37844274 Free PMC article.
Here, we introduce a method for providing such energy to strand displacement networks in a controlled fashion: an engineered DNA helicase, Rep-X, that transiently dehybridizes specific DNA complexes, enabling the strands in the complex to participate in downs …
Here, we introduce a method for providing such energy to strand displacement networks in a controlled fashion: an engineered D …
Toehold-Mediated Strand Displacement in Random Sequence Pools.
Mayer T, Oesinghaus L, Simmel FC. Mayer T, et al. J Am Chem Soc. 2023 Jan 11;145(1):634-644. doi: 10.1021/jacs.2c11208. Epub 2022 Dec 26. J Am Chem Soc. 2023. PMID: 36571481
Toehold-mediated strand displacement (TMSD) has been used extensively for molecular sensing and computing in DNA-based molecular circuits. ...We then investigate the influence of pools of random strands and find that the kinetics are determined by only a smal …
Toehold-mediated strand displacement (TMSD) has been used extensively for molecular sensing and computing in DNA-based molecul …
Timed Pulses in DNA Strand Displacement Reactions.
Bucci J, Irmisch P, Del Grosso E, Seidel R, Ricci F. Bucci J, et al. J Am Chem Soc. 2023 Sep 27;145(38):20968-20974. doi: 10.1021/jacs.3c06664. Epub 2023 Sep 14. J Am Chem Soc. 2023. PMID: 37710955 Free PMC article.
Inspired by naturally occurring regulatory mechanisms that allow complex temporal pulse features with programmable delays, we demonstrate here a strategy to achieve temporally programmed pulse output signals in DNA-based strand displacement reactions (SDRs). To achi …
Inspired by naturally occurring regulatory mechanisms that allow complex temporal pulse features with programmable delays, we demonstrate he …
Nucleic acid strand displacement - from DNA nanotechnology to translational regulation.
Simmel FC. Simmel FC. RNA Biol. 2023 Jan;20(1):154-163. doi: 10.1080/15476286.2023.2204565. RNA Biol. 2023. PMID: 37095744 Free PMC article.
Nucleic acid strand displacement reactions involve the competition of two or more DNA or RNA strands of similar sequence for binding to a complementary strand, and facilitate the isothermal replacement of an incumbent strand by an invader. The p …
Nucleic acid strand displacement reactions involve the competition of two or more DNA or RNA strands of similar sequenc …
Toehold-mediated strand displacement to measure released product from self-cleaving ribozymes.
Kapadia JB, Kharma N, Davis AN, Kamel N, Perreault J. Kapadia JB, et al. RNA. 2022 Feb;28(2):263-273. doi: 10.1261/rna.078823.121. Epub 2021 Dec 3. RNA. 2022. PMID: 34862273 Free PMC article.
These two DNA strands are perfectly complementary, but with a 3'-overhang of the fluorophore strand. These unpaired nucleotides act as a toehold, which is utilized by a detached cleaved fragment (coming from a self-cleaving hammerhead ribozyme) as the starting point …
These two DNA strands are perfectly complementary, but with a 3'-overhang of the fluorophore strand. These unpaired nucleotide …
5,217 results

Searches related to "strand displacement"