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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1952 1
1954 1
1966 1
1967 1
1968 1
1971 1
1972 1
1973 2
1974 4
1975 10
1976 7
1977 6
1978 19
1979 14
1980 10
1981 23
1982 11
1983 23
1984 31
1985 47
1986 45
1987 27
1988 33
1989 46
1990 47
1991 55
1992 65
1993 56
1994 68
1995 61
1996 77
1997 86
1998 99
1999 96
2000 108
2001 119
2002 111
2003 137
2004 160
2005 213
2006 214
2007 228
2008 291
2009 305
2010 313
2011 341
2012 403
2013 388
2014 440
2015 524
2016 582
2017 593
2018 608
2019 662
2020 753
2021 838
2022 874
2023 876
2024 935
2025 1282
2026 999

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12,712 results

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Page 1
The effect of neuroscience education on pain, disability, anxiety, and stress in chronic musculoskeletal pain.
Louw A, Diener I, Butler DS, Puentedura EJ. Louw A, et al. Arch Phys Med Rehabil. 2011 Dec;92(12):2041-56. doi: 10.1016/j.apmr.2011.07.198. Arch Phys Med Rehabil. 2011. PMID: 22133255 Review.
STUDY SELECTION: All experimental studies including randomized controlled trials (RCTs), nonrandomized clinical trials, and case series evaluating the effect of NE on pain, disability, anxiety, and stress for chronic MSK pain were considered for inclus …
STUDY SELECTION: All experimental studies including randomized controlled trials (RCTs), nonrandomized clinical trials, and case series eval …
Chronic Pain: Where the Body Meets the Brain.
Crofford LJ. Crofford LJ. Trans Am Clin Climatol Assoc. 2015;126:167-83. Trans Am Clin Climatol Assoc. 2015. PMID: 26330672 Free PMC article. Review.
Genetic, physiologic, and psychological factors associated with central pain amplification are beginning to be understood. One important contributor to chronic pain is perceived stress and stress response systems. We and others have shown a comp …
Genetic, physiologic, and psychological factors associated with central pain amplification are beginning to be understood. One import …
Endoplasmic reticulum stress: The underlying mechanism of chronic pain.
Liu T, Ji X, Zang H, Li Z, Yao W, Wan L, Zhang C, Zhang Y. Liu T, et al. Neurobiol Dis. 2024 Nov;202:106697. doi: 10.1016/j.nbd.2024.106697. Epub 2024 Oct 9. Neurobiol Dis. 2024. PMID: 39389155 Free article. Review.
Chronic pain (CP) affects over 30 % of the global population, imposing significant financial burdens on individuals and society. ...However, the mechanisms through which ER stress influences the most advanced centre-of-pain projections in the brain rem …
Chronic pain (CP) affects over 30 % of the global population, imposing significant financial burdens on individuals and societ …
The interaction between stress and chronic pain through the lens of threat learning.
Timmers I, Quaedflieg CWEM, Hsu C, Heathcote LC, Rovnaghi CR, Simons LE. Timmers I, et al. Neurosci Biobehav Rev. 2019 Dec;107:641-655. doi: 10.1016/j.neubiorev.2019.10.007. Epub 2019 Oct 14. Neurosci Biobehav Rev. 2019. PMID: 31622630 Free PMC article. Review.
Here, we argue that threat learning is a central mechanism and contributor, mediating the relationship between stress and chronic pain. We review the state of the art on (mal)adaptive learning in chronic pain, and on effects of stress and …
Here, we argue that threat learning is a central mechanism and contributor, mediating the relationship between stress and chronic …
Dysfunctional stress responses in chronic pain.
Woda A, Picard P, Dutheil F. Woda A, et al. Psychoneuroendocrinology. 2016 Sep;71:127-35. doi: 10.1016/j.psyneuen.2016.05.017. Epub 2016 May 22. Psychoneuroendocrinology. 2016. PMID: 27262345 Review.
Many dysfunctional and chronic pain conditions overlap. This review describes the different modes of chronic deregulation of the adaptive response to stress which may be a common factor for these conditions. ...The autonomic nervous system is another c …
Many dysfunctional and chronic pain conditions overlap. This review describes the different modes of chronic deregulati …
Chronic pain and comorbid posttraumatic stress disorder: Potential mechanisms, conceptualizations, and interventions.
Andersen TE, Ravn SL. Andersen TE, et al. Curr Opin Psychol. 2025 Apr;62:101990. doi: 10.1016/j.copsyc.2025.101990. Epub 2025 Jan 4. Curr Opin Psychol. 2025. PMID: 39818042 Free article. Review.
Posttraumatic stress disorder (PTSD) is a common comorbidity to chronic pain, among others due to potentially shared posttraumatic origin. ...This article provides a brief and up-to-date review of what we argue to be some of the most important studies within …
Posttraumatic stress disorder (PTSD) is a common comorbidity to chronic pain, among others due to potentially shared po …
Chronic pain in refugees with posttraumatic stress disorder (PTSD): A systematic review on patients' characteristics and specific interventions.
Rometsch-Ogioun El Sount C, Windthorst P, Denkinger J, Ziser K, Nikendei C, Kindermann D, Ringwald J, Renner V, Zipfel S, Junne F. Rometsch-Ogioun El Sount C, et al. J Psychosom Res. 2019 Mar;118:83-97. doi: 10.1016/j.jpsychores.2018.07.014. Epub 2018 Jul 30. J Psychosom Res. 2019. PMID: 30078503
OBJECTIVE: Chronic pain in patients with posttraumatic stress disorder (PTSD) is a frequent symptom and a complicating factor in the treatment of patients. ...A structured screening process in accordance with the PRISMA-statement was used with eligibility cri …
OBJECTIVE: Chronic pain in patients with posttraumatic stress disorder (PTSD) is a frequent symptom and a complicating …
Stress, epigenetic remodeling and FKBP51: Pathways to chronic pain vulnerability.
Morgan OB, Singleton S, Florea R, Hestehave S, Sarter T, Wozniak E, Mein CA, Hausch F, Bell CG, Géranton SM. Morgan OB, et al. Brain Behav Immun. 2025 Nov;130:106119. doi: 10.1016/j.bbi.2025.106119. Epub 2025 Sep 19. Brain Behav Immun. 2025. PMID: 40976404 Free article.
Chronic pain and post-traumatic stress disorder (PTSD) show striking similarities in their prevalence following injury and trauma respectively, with growing evidence suggesting shared vulnerability mechanisms, particularly through stress-related epigen …
Chronic pain and post-traumatic stress disorder (PTSD) show striking similarities in their prevalence following injury …
Effects of stress on the corticolimbic system: implications for chronic pain.
Vachon-Presseau E. Vachon-Presseau E. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Dec 20;87(Pt B):216-223. doi: 10.1016/j.pnpbp.2017.10.014. Epub 2017 Oct 25. Prog Neuropsychopharmacol Biol Psychiatry. 2018. PMID: 29079140 Review.
This overlap in effected circuitry provides a key point of comparison between stress and pain, and the similarities between the plasticity induced by chronic pain and chronic stress will be examined here. ...Finally, factors that have bee …
This overlap in effected circuitry provides a key point of comparison between stress and pain, and the similarities between th …
Endoplasmic reticular stress as an emerging therapeutic target for chronic pain: a narrative review.
Kim HS, Lee D, Shen S. Kim HS, et al. Br J Anaesth. 2024 Apr;132(4):707-724. doi: 10.1016/j.bja.2024.01.007. Epub 2024 Feb 19. Br J Anaesth. 2024. PMID: 38378384 Free PMC article. Review.
Although the role of ER stress in neurodegenerative disorders, metabolic disorders, and cancer has been well established, research on ER stress and chronic pain is still in its infancy. Here, we critically analyse preclinical studies and explore how ER …
Although the role of ER stress in neurodegenerative disorders, metabolic disorders, and cancer has been well established, research on …
12,712 results
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