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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1995 1
1996 1
1997 3
1998 3
1999 5
2000 1
2001 6
2002 5
2003 4
2004 7
2005 6
2006 8
2007 3
2008 5
2009 7
2010 5
2011 7
2012 10
2013 13
2014 7
2015 10
2016 2
2017 7
2018 2
2019 7
2020 7
2021 14
2022 7
2023 1
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150 results
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Page 1
An apical membrane complex for triggering rhoptry exocytosis and invasion in Toxoplasma.
Sparvoli D, Delabre J, Penarete-Vargas DM, Kumar Mageswaran S, Tsypin LM, Heckendorn J, Theveny L, Maynadier M, Mendonça Cova M, Berry-Sterkers L, Guérin A, Dubremetz JF, Urbach S, Striepen B, Turkewitz AP, Chang YW, Lebrun M. Sparvoli D, et al. Among authors: striepen b. EMBO J. 2022 Nov 17;41(22):e111158. doi: 10.15252/embj.2022111158. Epub 2022 Oct 17. EMBO J. 2022. PMID: 36245278 Free PMC article.
Long-read assembly and comparative evidence-based reanalysis of Cryptosporidium genome sequences reveal expanded transporter repertoire and duplication of entire chromosome ends including subtelomeric regions.
Baptista RP, Li Y, Sateriale A, Sanders MJ, Brooks KL, Tracey A, Ansell BRE, Jex AR, Cooper GW, Smith ED, Xiao R, Dumaine JE, Georgeson P, Pope BJ, Berriman M, Striepen B, Cotton JA, Kissinger JC. Baptista RP, et al. Among authors: striepen b. Genome Res. 2022 Jan;32(1):203-213. doi: 10.1101/gr.275325.121. Epub 2021 Nov 11. Genome Res. 2022. PMID: 34764149 Free PMC article.
Repurposing Infectious Disease Hits as Anti-Cryptosporidium Leads.
Hulverson MA, Choi R, McCloskey MC, Whitman GR, Ojo KK, Michaels SA, Somepalli M, Love MS, McNamara CW, Rabago LM, Barrett LK, Verlinde CLMJ, Arnold SLM, Striepen B, Jimenez-Alfaro D, Ballell L, Fernández E, Greenwood MN, Las Heras L, Calderón F, Van Voorhis WC. Hulverson MA, et al. Among authors: striepen b. ACS Infect Dis. 2021 May 14;7(5):1275-1282. doi: 10.1021/acsinfecdis.1c00076. Epub 2021 Mar 19. ACS Infect Dis. 2021. PMID: 33740373
An Alveolata secretory machinery adapted to parasite host cell invasion.
Aquilini E, Cova MM, Mageswaran SK, Dos Santos Pacheco N, Sparvoli D, Penarete-Vargas DM, Najm R, Graindorge A, Suarez C, Maynadier M, Berry-Sterkers L, Urbach S, Fahy PR, Guérin AN, Striepen B, Dubremetz JF, Chang YW, Turkewitz AP, Lebrun M. Aquilini E, et al. Among authors: striepen b. Nat Microbiol. 2021 Apr;6(4):425-434. doi: 10.1038/s41564-020-00854-z. Epub 2021 Jan 25. Nat Microbiol. 2021. PMID: 33495622 Free PMC article.
Bicyclic azetidines kill the diarrheal pathogen Cryptosporidium in mice by inhibiting parasite phenylalanyl-tRNA synthetase.
Vinayak S, Jumani RS, Miller P, Hasan MM, McLeod BI, Tandel J, Stebbins EE, Teixeira JE, Borrel J, Gonse A, Zhang M, Yu X, Wernimont A, Walpole C, Eckley S, Love MS, McNamara CW, Sharma M, Sharma A, Scherer CA, Kato N, Schreiber SL, Melillo B, Striepen B, Huston CD, Comer E. Vinayak S, et al. Among authors: striepen b. Sci Transl Med. 2020 Sep 30;12(563):eaba8412. doi: 10.1126/scitranslmed.aba8412. Sci Transl Med. 2020. PMID: 32998973 Free PMC article.
Cryptosporidium parvum.
Dumaine JE, Tandel J, Striepen B. Dumaine JE, et al. Among authors: striepen b. Trends Parasitol. 2020 May;36(5):485-486. doi: 10.1016/j.pt.2019.11.003. Epub 2019 Dec 10. Trends Parasitol. 2020. PMID: 31836286 No abstract available.
The cat is out of the bag: How parasites know their hosts.
English ED, Striepen B. English ED, et al. Among authors: striepen b. PLoS Biol. 2019 Sep 5;17(9):e3000446. doi: 10.1371/journal.pbio.3000446. eCollection 2019 Sep. PLoS Biol. 2019. PMID: 31487278 Free PMC article.
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Baragaña B, Forte B, Choi R, Nakazawa Hewitt S, Bueren-Calabuig JA, Pisco JP, Peet C, Dranow DM, Robinson DA, Jansen C, Norcross NR, Vinayak S, Anderson M, Brooks CF, Cooper CA, Damerow S, Delves M, Dowers K, Duffy J, Edwards TE, Hallyburton I, Horst BG, Hulverson MA, Ferguson L, Jiménez-Díaz MB, Jumani RS, Lorimer DD, Love MS, Maher S, Matthews H, McNamara CW, Miller P, O'Neill S, Ojo KK, Osuna-Cabello M, Pinto E, Post J, Riley J, Rottmann M, Sanz LM, Scullion P, Sharma A, Shepherd SM, Shishikura Y, Simeons FRC, Stebbins EE, Stojanovski L, Straschil U, Tamaki FK, Tamjar J, Torrie LS, Vantaux A, Witkowski B, Wittlin S, Yogavel M, Zuccotto F, Angulo-Barturen I, Sinden R, Baum J, Gamo FJ, Mäser P, Kyle DE, Winzeler EA, Myler PJ, Wyatt PG, Floyd D, Matthews D, Sharma A, Striepen B, Huston CD, Gray DW, Fairlamb AH, Pisliakov AV, Walpole C, Read KD, Van Voorhis WC, Gilbert IH. Baragaña B, et al. Among authors: striepen b. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7015-7020. doi: 10.1073/pnas.1814685116. Epub 2019 Mar 20. Proc Natl Acad Sci U S A. 2019. PMID: 30894487 Free PMC article.
Cryptosporidium.
Gibson AR, Striepen B. Gibson AR, et al. Among authors: striepen b. Curr Biol. 2018 Mar 5;28(5):R193-R194. doi: 10.1016/j.cub.2017.11.070. Curr Biol. 2018. PMID: 29510102 Free article. Review.
Two essential Thioredoxins mediate apicoplast biogenesis, protein import, and gene expression in Toxoplasma gondii.
Biddau M, Bouchut A, Major J, Saveria T, Tottey J, Oka O, van-Lith M, Jennings KE, Ovciarikova J, DeRocher A, Striepen B, Waller RF, Parsons M, Sheiner L. Biddau M, et al. Among authors: striepen b. PLoS Pathog. 2018 Feb 22;14(2):e1006836. doi: 10.1371/journal.ppat.1006836. eCollection 2018 Feb. PLoS Pathog. 2018. PMID: 29470517 Free PMC article.
A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis.
Manjunatha UH, Vinayak S, Zambriski JA, Chao AT, Sy T, Noble CG, Bonamy GMC, Kondreddi RR, Zou B, Gedeck P, Brooks CF, Herbert GT, Sateriale A, Tandel J, Noh S, Lakshminarayana SB, Lim SH, Goodman LB, Bodenreider C, Feng G, Zhang L, Blasco F, Wagner J, Leong FJ, Striepen B, Diagana TT. Manjunatha UH, et al. Among authors: striepen b. Nature. 2017 Jun 15;546(7658):376-380. doi: 10.1038/nature22337. Epub 2017 May 31. Nature. 2017. PMID: 28562588 Free PMC article.
Bumped-Kinase Inhibitors for Cryptosporidiosis Therapy.
Hulverson MA, Vinayak S, Choi R, Schaefer DA, Castellanos-Gonzalez A, Vidadala RSR, Brooks CF, Herbert GT, Betzer DP, Whitman GR, Sparks HN, Arnold SLM, Rivas KL, Barrett LK, White AC Jr, Maly DJ, Riggs MW, Striepen B, Van Voorhis WC, Ojo KK. Hulverson MA, et al. Among authors: striepen b. J Infect Dis. 2017 Apr 15;215(8):1275-1284. doi: 10.1093/infdis/jix120. J Infect Dis. 2017. PMID: 28329187 Free PMC article.
The Import of Proteins into the Mitochondrion of Toxoplasma gondii.
van Dooren GG, Yeoh LM, Striepen B, McFadden GI. van Dooren GG, et al. Among authors: striepen b. J Biol Chem. 2016 Sep 9;291(37):19335-50. doi: 10.1074/jbc.M116.725069. Epub 2016 Jul 25. J Biol Chem. 2016. PMID: 27458014 Free PMC article.
Genetic modification of the diarrhoeal pathogen Cryptosporidium parvum.
Vinayak S, Pawlowic MC, Sateriale A, Brooks CF, Studstill CJ, Bar-Peled Y, Cipriano MJ, Striepen B. Vinayak S, et al. Among authors: striepen b. Nature. 2015 Jul 23;523(7561):477-80. doi: 10.1038/nature14651. Epub 2015 Jul 15. Nature. 2015. PMID: 26176919 Free PMC article.
Lipid kinases are essential for apicoplast homeostasis in Toxoplasma gondii.
Daher W, Morlon-Guyot J, Sheiner L, Lentini G, Berry L, Tawk L, Dubremetz JF, Wengelnik K, Striepen B, Lebrun M. Daher W, et al. Among authors: striepen b. Cell Microbiol. 2015 Apr;17(4):559-78. doi: 10.1111/cmi.12383. Epub 2014 Nov 22. Cell Microbiol. 2015. PMID: 25329540 Free PMC article.
A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium.
Checkley W, White AC Jr, Jaganath D, Arrowood MJ, Chalmers RM, Chen XM, Fayer R, Griffiths JK, Guerrant RL, Hedstrom L, Huston CD, Kotloff KL, Kang G, Mead JR, Miller M, Petri WA Jr, Priest JW, Roos DS, Striepen B, Thompson RC, Ward HD, Van Voorhis WA, Xiao L, Zhu G, Houpt ER. Checkley W, et al. Among authors: striepen b. Lancet Infect Dis. 2015 Jan;15(1):85-94. doi: 10.1016/S1473-3099(14)70772-8. Epub 2014 Sep 29. Lancet Infect Dis. 2015. PMID: 25278220 Free PMC article. Review.
Cell division in apicomplexan parasites.
Francia ME, Striepen B. Francia ME, et al. Among authors: striepen b. Nat Rev Microbiol. 2014 Feb;12(2):125-36. doi: 10.1038/nrmicro3184. Epub 2014 Jan 2. Nat Rev Microbiol. 2014. PMID: 24384598 Review.
Validation of IMP dehydrogenase inhibitors in a mouse model of cryptosporidiosis.
Gorla SK, McNair NN, Yang G, Gao S, Hu M, Jala VR, Haribabu B, Striepen B, Cuny GD, Mead JR, Hedstrom L. Gorla SK, et al. Among authors: striepen b. Antimicrob Agents Chemother. 2014;58(3):1603-14. doi: 10.1128/AAC.02075-13. Epub 2013 Dec 23. Antimicrob Agents Chemother. 2014. PMID: 24366728 Free PMC article.
A nucleolar AAA-NTPase is required for parasite division.
Suvorova ES, Radke JB, Ting LM, Vinayak S, Alvarez CA, Kratzer S, Kim K, Striepen B, White MW. Suvorova ES, et al. Among authors: striepen b. Mol Microbiol. 2013 Oct;90(2):338-55. doi: 10.1111/mmi.12367. Epub 2013 Sep 11. Mol Microbiol. 2013. PMID: 23964771 Free PMC article.
The algal past and parasite present of the apicoplast.
van Dooren GG, Striepen B. van Dooren GG, et al. Among authors: striepen b. Annu Rev Microbiol. 2013;67:271-89. doi: 10.1146/annurev-micro-092412-155741. Epub 2013 Jun 26. Annu Rev Microbiol. 2013. PMID: 23808340 Review.
Protein sorting in complex plastids.
Sheiner L, Striepen B. Sheiner L, et al. Among authors: striepen b. Biochim Biophys Acta. 2013 Feb;1833(2):352-9. doi: 10.1016/j.bbamcr.2012.05.030. Epub 2012 Jun 7. Biochim Biophys Acta. 2013. PMID: 22683761 Free PMC article. Review.
What do human parasites do with a chloroplast anyway?
Nair SC, Striepen B. Nair SC, et al. Among authors: striepen b. PLoS Biol. 2011 Aug;9(8):e1001137. doi: 10.1371/journal.pbio.1001137. Epub 2011 Aug 30. PLoS Biol. 2011. PMID: 21912515 Free PMC article. Review.
Prodrug activation by Cryptosporidium thymidine kinase.
Sun XE, Sharling L, Muthalagi M, Mudeppa DG, Pankiewicz KW, Felczak K, Rathod PK, Mead J, Striepen B, Hedstrom L. Sun XE, et al. Among authors: striepen b. J Biol Chem. 2010 May 21;285(21):15916-22. doi: 10.1074/jbc.M110.101543. Epub 2010 Mar 15. J Biol Chem. 2010. PMID: 20231284 Free PMC article.
Malaria: The gatekeeper revealed.
Reiff SB, Striepen B. Reiff SB, et al. Among authors: striepen b. Nature. 2009 Jun 18;459(7249):918-9. doi: 10.1038/459918a. Nature. 2009. PMID: 19536248 No abstract available.
A dynamin is required for the biogenesis of secretory organelles in Toxoplasma gondii.
Breinich MS, Ferguson DJ, Foth BJ, van Dooren GG, Lebrun M, Quon DV, Striepen B, Bradley PJ, Frischknecht F, Carruthers VB, Meissner M. Breinich MS, et al. Among authors: striepen b. Curr Biol. 2009 Feb 24;19(4):277-86. doi: 10.1016/j.cub.2009.01.039. Epub 2009 Feb 12. Curr Biol. 2009. PMID: 19217293 Free PMC article.
Toxoplasma gondii Tic20 is essential for apicoplast protein import.
van Dooren GG, Tomova C, Agrawal S, Humbel BM, Striepen B. van Dooren GG, et al. Among authors: striepen b. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13574-9. doi: 10.1073/pnas.0803862105. Epub 2008 Aug 29. Proc Natl Acad Sci U S A. 2008. PMID: 18757752 Free PMC article.
Dynamics of neutrophil migration in lymph nodes during infection.
Chtanova T, Schaeffer M, Han SJ, van Dooren GG, Nollmann M, Herzmark P, Chan SW, Satija H, Camfield K, Aaron H, Striepen B, Robey EA. Chtanova T, et al. Among authors: striepen b. Immunity. 2008 Sep 19;29(3):487-96. doi: 10.1016/j.immuni.2008.07.012. Epub 2008 Aug 21. Immunity. 2008. PMID: 18718768 Free PMC article.
Switching parasite proteins on and off.
Striepen B. Striepen B. Nat Methods. 2007 Dec;4(12):999-1000. doi: 10.1038/nmeth1207-999. Nat Methods. 2007. PMID: 18049467 No abstract available.
Make it or take it: fatty acid metabolism of apicomplexan parasites.
Mazumdar J, Striepen B. Mazumdar J, et al. Among authors: striepen b. Eukaryot Cell. 2007 Oct;6(10):1727-35. doi: 10.1128/EC.00255-07. Epub 2007 Aug 22. Eukaryot Cell. 2007. PMID: 17715365 Free PMC article. Review. No abstract available.
Adenosine kinase from Cryptosporidium parvum.
Galazka J, Striepen B, Ullman B. Galazka J, et al. Among authors: striepen b. Mol Biochem Parasitol. 2006 Oct;149(2):223-30. doi: 10.1016/j.molbiopara.2006.06.001. Epub 2006 Jun 27. Mol Biochem Parasitol. 2006. PMID: 16879885
IMP dehydrogenase from the protozoan parasite Toxoplasma gondii.
Sullivan WJ Jr, Dixon SE, Li C, Striepen B, Queener SF. Sullivan WJ Jr, et al. Among authors: striepen b. Antimicrob Agents Chemother. 2005 Jun;49(6):2172-9. doi: 10.1128/AAC.49.6.2172-2179.2005. Antimicrob Agents Chemother. 2005. PMID: 15917510 Free PMC article.
Genetic rescue of a Toxoplasma gondii conditional cell cycle mutant.
White MW, Jerome ME, Vaishnava S, Guerini M, Behnke M, Striepen B. White MW, et al. Among authors: striepen b. Mol Microbiol. 2005 Feb;55(4):1060-71. doi: 10.1111/j.1365-2958.2004.04471.x. Mol Microbiol. 2005. PMID: 15686554 Free article.
Gene transfer in the evolution of parasite nucleotide biosynthesis.
Striepen B, Pruijssers AJ, Huang J, Li C, Gubbels MJ, Umejiego NN, Hedstrom L, Kissinger JC. Striepen B, et al. Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):3154-9. doi: 10.1073/pnas.0304686101. Epub 2004 Feb 18. Proc Natl Acad Sci U S A. 2004. PMID: 14973196 Free PMC article.
Isolation and characterization of TgVP1, a type I vacuolar H+-translocating pyrophosphatase from Toxoplasma gondii. The dynamics of its subcellular localization and the cellular effects of a diphosphonate inhibitor.
Drozdowicz YM, Shaw M, Nishi M, Striepen B, Liwinski HA, Roos DS, Rea PA. Drozdowicz YM, et al. Among authors: striepen b. J Biol Chem. 2003 Jan 10;278(2):1075-85. doi: 10.1074/jbc.M209436200. Epub 2002 Oct 30. J Biol Chem. 2003. PMID: 12411435 Free article.
Genetic complementation in apicomplexan parasites.
Striepen B, White MW, Li C, Guerini MN, Malik SB, Logsdon JM Jr, Liu C, Abrahamsen MS. Striepen B, et al. Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6304-9. doi: 10.1073/pnas.092525699. Epub 2002 Apr 16. Proc Natl Acad Sci U S A. 2002. PMID: 11959921 Free PMC article.
Transport and trafficking: Toxoplasma as a model for Plasmodium.
Roos DS, Crawford MJ, Donald RG, Fohl LM, Hager KM, Kissinger JC, Reynolds MG, Striepen B, Sullivan WJ Jr. Roos DS, et al. Among authors: striepen b. Novartis Found Symp. 1999;226:176-95; discussion 195-8. doi: 10.1002/9780470515730.ch13. Novartis Found Symp. 1999. PMID: 10645546 Review.
Origin, targeting, and function of the apicomplexan plastid.
Roos DS, Crawford MJ, Donald RG, Kissinger JC, Klimczak LJ, Striepen B. Roos DS, et al. Among authors: striepen b. Curr Opin Microbiol. 1999 Aug;2(4):426-32. doi: 10.1016/S1369-5274(99)80075-7. Curr Opin Microbiol. 1999. PMID: 10458993 Free article. Review.
Glycosyl-phosphatidylinositols in protozoa structure, biosynthesis and intracellular localisation.
Zinecker CF, Gerold P, Azzouz N, Striepen B, Schmidt A, Berhe S, Kimmel J, Keddes MH, Blackman MJ, Schofield L, Ogun S, Damm JB, Melgers PA, Koolen M, Gerwig GJ, Vliegenhardt JF, Dubremetz JF, Holder AA, Eckert V, Capdeville Y, Tachado SD, Schwarz RT. Zinecker CF, et al. Among authors: striepen b. Indian J Biochem Biophys. 1997 Feb-Apr;34(1-2):105-9. Indian J Biochem Biophys. 1997. PMID: 9343937