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Page 1
Sucralose.
[No authors listed] [No authors listed] 2025 Dec 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2025 Dec 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000579 Free Books & Documents. Review.
Sucralose has been found in the breastmilk of some nursing mothers who report consuming artificially sweetened beverages and sweetener packets in the past 24 hours and in all women given a sucralose-sweetened drinks. Sucralose is poorly absorbed after oral in …
Sucralose has been found in the breastmilk of some nursing mothers who report consuming artificially sweetened beverages and sweetene …
Effect of sucralose and aspartame on glucose metabolism and gut hormones.
Ahmad SY, Friel JK, Mackay DS. Ahmad SY, et al. Nutr Rev. 2020 Sep 1;78(9):725-746. doi: 10.1093/nutrit/nuz099. Nutr Rev. 2020. PMID: 32065635 Review.
Here, the available evidence of the effects of aspartame and sucralose consumption on glucose metabolism and gut hormones is reviewed. A majority of studies have found that consumption of aspartame or sucralose has no effect on concentrations of blood glucose, insul …
Here, the available evidence of the effects of aspartame and sucralose consumption on glucose metabolism and gut hormones is reviewed …
Toxicological and pharmacokinetic properties of sucralose-6-acetate and its parent sucralose: in vitro screening assays.
Schiffman SS, Scholl EH, Furey TS, Nagle HT. Schiffman SS, et al. J Toxicol Environ Health B Crit Rev. 2023 Aug 18;26(6):307-341. doi: 10.1080/10937404.2023.2213903. Epub 2023 May 29. J Toxicol Environ Health B Crit Rev. 2023. PMID: 37246822 Free article. Review.
The purpose of this study was to determine the toxicological and pharmacokinetic properties of sucralose-6-acetate, a structural analog of the artificial sweetener sucralose. Sucralose-6-acetate is an intermediate and impurity in the manufacture of sucralo …
The purpose of this study was to determine the toxicological and pharmacokinetic properties of sucralose-6-acetate, a structural anal …
Potential Effects of Sucralose and Saccharin on Gut Microbiota: A Review.
Del Pozo S, Gómez-Martínez S, Díaz LE, Nova E, Urrialde R, Marcos A. Del Pozo S, et al. Nutrients. 2022 Apr 18;14(8):1682. doi: 10.3390/nu14081682. Nutrients. 2022. PMID: 35458244 Free PMC article. Review.
Although there is no consensus, current evidence indicates that sucralose and saccharin could influence the gut microbiota. The aim of this study was to analyze the existing scientific evidence on the effects of saccharin and sucralose consumption on gut microbiota …
Although there is no consensus, current evidence indicates that sucralose and saccharin could influence the gut microbiota. The aim o …
Sucralose.
AlDeeb OA, Mahgoub H, Foda NH. AlDeeb OA, et al. Profiles Drug Subst Excip Relat Methodol. 2013;38:423-62. doi: 10.1016/B978-0-12-407691-4.00010-1. Profiles Drug Subst Excip Relat Methodol. 2013. PMID: 23668410 Review.
The ADME profile covered all absorption, distribution, metabolism, and elimination data in addition to pharmacokinetics and pharmacological effects of sucralose. Some nutritional aspects for sucralose in obesity and diabetes are also presented. Both chemical and mic …
The ADME profile covered all absorption, distribution, metabolism, and elimination data in addition to pharmacokinetics and pharmacological …
The Effects of Non-Nutritive Artificial Sweeteners, Aspartame and Sucralose, on the Gut Microbiome in Healthy Adults: Secondary Outcomes of a Randomized Double-Blinded Crossover Clinical Trial.
Ahmad SY, Friel J, Mackay D. Ahmad SY, et al. Nutrients. 2020 Nov 6;12(11):3408. doi: 10.3390/nu12113408. Nutrients. 2020. PMID: 33171964 Free PMC article. Clinical Trial.
This study aimed to determine the effect of sucralose and aspartame consumption on gut microbiota composition using realistic doses of NNSs. ...These findings suggest that daily repeated consumption of pure aspartame or sucralose in doses reflective of typical high …
This study aimed to determine the effect of sucralose and aspartame consumption on gut microbiota composition using realistic doses o …
Sucralose Consumption Ablates Cancer Immunotherapy Response through Microbiome Disruption.
Morder KM, Nguyen M, Wilfahrt DN, Dahmani ZL, Burr ABP, Xie B, Morikone M, Nieves-Rosado H, Gunn WG, Hurd DE, Wang H, Mullett SJ, Bossong K, Gelhaus SL, Rajasundaram D, Kane LP, Delgoffe GM, Das J, Davar D, Overacre-Delgoffe AE. Morder KM, et al. Cancer Discov. 2025 Nov 3;15(11):2278-2297. doi: 10.1158/2159-8290.CD-25-0247. Cancer Discov. 2025. PMID: 40742298 Free PMC article.
Sucralose consumption is associated with a reduction in microbiota-accessible arginine, and amino acid supplementation or fecal microbiome transfer from anti-PD-1 responder mice completely restores T-cell function and immunotherapy response. Overall, sucralose consu …
Sucralose consumption is associated with a reduction in microbiota-accessible arginine, and amino acid supplementation or fecal micro …
The dietary sweetener sucralose is a negative modulator of T cell-mediated responses.
Zani F, Blagih J, Gruber T, Buck MD, Jones N, Hennequart M, Newell CL, Pilley SE, Soro-Barrio P, Kelly G, Legrave NM, Cheung EC, Gilmore IS, Gould AP, Garcia-Caceres C, Vousden KH. Zani F, et al. Nature. 2023 Mar;615(7953):705-711. doi: 10.1038/s41586-023-05801-6. Epub 2023 Mar 15. Nature. 2023. PMID: 36922598 Free PMC article.
In this study, we show that the intake of high doses of sucralose in mice results in immunomodulatory effects by limiting T cell proliferation and T cell differentiation. Mechanistically, sucralose affects the membrane order of T cells, accompanied by a reduced effi …
In this study, we show that the intake of high doses of sucralose in mice results in immunomodulatory effects by limiting T cell prol …
Sucralose: A Review of Environmental, Oxidative and Genomic Stress.
Tkach VV, Morozova TV, Gaivão IOM, Miranda NG, Ivanushko YG, Martins JIFP, Barros AN. Tkach VV, et al. Nutrients. 2025 Jul 1;17(13):2199. doi: 10.3390/nu17132199. Nutrients. 2025. PMID: 40647303 Free PMC article. Review.
Reports of sucralose-induced oxidative stress further highlight the need for caution in its continued use, particularly in sensitive formulations. Given its widespread presence and resistance to degradation, further investigation into the environmental and biological safet …
Reports of sucralose-induced oxidative stress further highlight the need for caution in its continued use, particularly in sensitive …
Short-term impact of sucralose consumption on the metabolic response and gut microbiome of healthy adults.
Thomson P, Santibañez R, Aguirre C, Galgani JE, Garrido D. Thomson P, et al. Br J Nutr. 2019 Oct 28;122(8):856-862. doi: 10.1017/S0007114519001570. Epub 2019 Sep 13. Br J Nutr. 2019. PMID: 31258108 Clinical Trial.
Sucralose is an artificial non-nutritive sweetener used in foods aimed to reduce sugar and energy intake. ...However, it highlights the need to address individual responses to sucralose....
Sucralose is an artificial non-nutritive sweetener used in foods aimed to reduce sugar and energy intake. ...However, it highlights t …
1,379 results