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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 1
1982 1
1983 1
1985 1
1990 3
1994 1
1996 4
1997 1
1998 2
1999 2
2000 12
2001 1
2002 2
2003 4
2004 3
2005 1
2006 3
2007 8
2008 8
2009 14
2010 19
2011 25
2012 18
2013 32
2014 26
2015 32
2016 40
2017 42
2018 37
2019 46
2020 44
2021 18
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Page 1
Sucralose.
AlDeeb OA, Mahgoub H, Foda NH. AlDeeb OA, et al. Profiles Drug Subst Excip Relat Methodol. 2013;38:423-62. doi: 10.1016/B978-0-12-407691-4.00010-1. Profiles Drug Subst Excip Relat Methodol. 2013. PMID: 23668410 Review.
The ADME profile covered all absorption, distribution, metabolism, and elimination data in addition to pharmacokinetics and pharmacological effects of sucralose. Some nutritional aspects for sucralose in obesity and diabetes are also presented. Both chemical …
The ADME profile covered all absorption, distribution, metabolism, and elimination data in addition to pharmacokinetics and pharmacol …
Sucralose, a synthetic organochlorine sweetener: overview of biological issues.
Schiffman SS, Rother KI. Schiffman SS, et al. J Toxicol Environ Health B Crit Rev. 2013;16(7):399-451. doi: 10.1080/10937404.2013.842523. J Toxicol Environ Health B Crit Rev. 2013. PMID: 24219506 Free PMC article. Review.
P-gp and CYP are key components of the presystemic detoxification system involved in first-pass drug metabolism. The effect of sucralose on first-pass drug metabolism in humans, however, has not yet been determined. ...Taken together, these findings indicate …
P-gp and CYP are key components of the presystemic detoxification system involved in first-pass drug metabolism. The effect of suc …
Sucralose-Enhanced Degradation of Electronic Cigarette Liquids during Vaping.
Duell AK, McWhirter KJ, Korzun T, Strongin RM, Peyton DH. Duell AK, et al. Chem Res Toxicol. 2019 Jun 17;32(6):1241-1249. doi: 10.1021/acs.chemrestox.9b00047. Epub 2019 May 23. Chem Res Toxicol. 2019. PMID: 31079450
Sucralose was found to be subject to degradation when included in propylene glycol + glycerol based e-liquids and vaped; the presence of sucralose in the e-liquids also resulted in altered and enhanced solvent degradation. ...Quantities of sucralose …
Sucralose was found to be subject to degradation when included in propylene glycol + glycerol based e-liquids and vaped; the p …
[Kinetics and Mechanism of Sucralose Degradation in Water Using UV-activated Persulfate Process].
Yu Y, Lu JX, LÜ Z, Peng MG, Xu BK, Du ED, Zheng L. Yu Y, et al. Huan Jing Ke Xue. 2020 Oct 8;41(10):4626-4635. doi: 10.13227/j.hjkx.202001046. Huan Jing Ke Xue. 2020. PMID: 33124395 Chinese.
The degradation of emerging pollutant artificial sweetener sucralose (SUC) using UV/persulfate (UV/PS). ...It is reported that, compared with single UV or PS, the degradation of SUC by UV/PS was more obvious. The degradation rate constants increased wi …
The degradation of emerging pollutant artificial sweetener sucralose (SUC) using UV/persulfate (UV/PS). ...It is reported that …
Effect of sucralose and aspartame on glucose metabolism and gut hormones.
Ahmad SY, Friel JK, Mackay DS. Ahmad SY, et al. Nutr Rev. 2020 Sep 1;78(9):725-746. doi: 10.1093/nutrit/nuz099. Nutr Rev. 2020. PMID: 32065635 Review.
However, the potential effects of non-nutritive sweeteners on glucose metabolism and gut hormones have not been determined definitively. Here, the available evidence of the effects of aspartame and sucralose consumption on glucose metabolism and gut hormones …
However, the potential effects of non-nutritive sweeteners on glucose metabolism and gut hormones have not been determined definitive …
Artificial sweeteners induce glucose intolerance by altering the gut microbiota.
Suez J, Korem T, Zeevi D, Zilberman-Schapira G, Thaiss CA, Maza O, Israeli D, Zmora N, Gilad S, Weinberger A, Kuperman Y, Harmelin A, Kolodkin-Gal I, Shapiro H, Halpern Z, Segal E, Elinav E. Suez J, et al. Nature. 2014 Oct 9;514(7521):181-6. doi: 10.1038/nature13793. Epub 2014 Sep 17. Nature. 2014. PMID: 25231862
Sucralose affects glycemic and hormonal responses to an oral glucose load.
Pepino MY, Tiemann CD, Patterson BW, Wice BM, Klein S. Pepino MY, et al. Diabetes Care. 2013 Sep;36(9):2530-5. doi: 10.2337/dc12-2221. Epub 2013 Apr 30. Diabetes Care. 2013. PMID: 23633524 Free PMC article. Clinical Trial.
OBJECTIVE: Nonnutritive sweeteners (NNS), such as sucralose, have been reported to have metabolic effects in animal models. However, the relevance of these findings to human subjects is not clear. We evaluated the acute effects of sucralose ingestion on the metaboli …
OBJECTIVE: Nonnutritive sweeteners (NNS), such as sucralose, have been reported to have metabolic effects in animal models. However, …
Widespread sucralose exposure in a randomized clinical trial in healthy young adults.
Sylvetsky AC, Walter PJ, Garraffo HM, Robien K, Rother KI. Sylvetsky AC, et al. Am J Clin Nutr. 2017 Apr;105(4):820-823. doi: 10.3945/ajcn.116.144402. Epub 2017 Feb 22. Am J Clin Nutr. 2017. PMID: 28228424 Free PMC article. Clinical Trial.
After the run-in, participants were randomly assigned to consume diet soda containing sucralose or carbonated water (control) 3 times/d for 1 wk. Food diaries were maintained throughout the study, and a spot urine sample was collected at each visit.Results: At baseline, 8 …
After the run-in, participants were randomly assigned to consume diet soda containing sucralose or carbonated water (control) 3 times …
Short-Term Consumption of Sucralose with, but Not without, Carbohydrate Impairs Neural and Metabolic Sensitivity to Sugar in Humans.
Dalenberg JR, Patel BP, Denis R, Veldhuizen MG, Nakamura Y, Vinke PC, Luquet S, Small DM. Dalenberg JR, et al. Cell Metab. 2020 Mar 3;31(3):493-502.e7. doi: 10.1016/j.cmet.2020.01.014. Cell Metab. 2020. PMID: 32130881 Free PMC article. Clinical Trial.
Whether a similar relationship exists for no- or low-calorie "diet" drinks is a subject of intensive debate and controversy. Here, we demonstrate that consuming seven sucralose-sweetened beverages with, but not without, a carbohydrate over 10 days decreases insulin sensiti …
Whether a similar relationship exists for no- or low-calorie "diet" drinks is a subject of intensive debate and controversy. Here, we demons …
Degradation of sucralose in groundwater and implications for age dating contaminated groundwater.
Robertson WD, Van Stempvoort DR, Spoelstra J, Brown SJ, Schiff SL. Robertson WD, et al. Water Res. 2016 Jan 1;88:653-660. doi: 10.1016/j.watres.2015.10.051. Epub 2015 Nov 11. Water Res. 2016. PMID: 26575474
A shrinking sucralose plume in 2014, compared to earlier sampling, during this period when sucralose use was likely increasing, provides clear evidence of degradation. ...Even though sucralose degradation is noted in the Long Point plume, its ub …
A shrinking sucralose plume in 2014, compared to earlier sampling, during this period when sucralose use was likely increasing …
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