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The 6-hydroxychromanol derivative SUL-109 ameliorates renal injury after deep hypothermia and rewarming in rats.
Vogelaar PC, Roorda M, de Vrij EL, Houwertjes MC, Goris M, Bouma H, van der Graaf AC, Krenning G, Henning RH. Vogelaar PC, et al. Nephrol Dial Transplant. 2018 Dec 1;33(12):2128-2138. doi: 10.1093/ndt/gfy080. Nephrol Dial Transplant. 2018. PMID: 29660027
SUL-109 and SUL-121 ameliorated tubular kidney damage, preserved mitochondrial mass and maintained cortical adenosine 5'-triphosphate (ATP) levels, although SUL-121 did not reduce protein nitrosylation. ...Therefore SUL-109 offers a promi
SUL-109 and SUL-121 ameliorated tubular kidney damage, preserved mitochondrial mass and maintained cortical adenosine 5
The 6-chromanol derivate SUL-109 enables prolonged hypothermic storage of adipose tissue-derived stem cells.
Hajmousa G, Vogelaar P, Brouwer LA, van der Graaf AC, Henning RH, Krenning G. Hajmousa G, et al. Biomaterials. 2017 Mar;119:43-52. doi: 10.1016/j.biomaterials.2016.12.008. Epub 2016 Dec 9. Biomaterials. 2017. PMID: 28006657
Here, the ability of the cell culture medium additive SUL-109, a modified 6-chromanol, to protect ASC from hypothermia and rewarming damage is examined. ...SUL-109 does not reduce the multilineage differentiation capacity of ASC. SUL-109
Here, the ability of the cell culture medium additive SUL-109, a modified 6-chromanol, to protect ASC from hypothermia and rew …
SUL-109 Protects Hematopoietic Stem Cells from Apoptosis Induced by Short-Term Hypothermic Preservation and Maintains Their Engraftment Potential.
Aerts-Kaya FSF, Visser TP, Pervin B, Mammadova A, Özyüncü Ö, Wagemaker G, Uçkan-Çetinkaya FD. Aerts-Kaya FSF, et al. Biol Blood Marrow Transplant. 2020 Apr;26(4):634-642. doi: 10.1016/j.bbmt.2019.12.770. Epub 2020 Jan 7. Biol Blood Marrow Transplant. 2020. PMID: 31917271
The newly developed 6-hydroxychromanol derivate SUL-109 was shown to provide protection during hypothermic storage of several cell lines, but has not been evaluated in hematopoietic stem cells (HSCs). ...SUL-109-containing cultures were stored at 4°C f …
The newly developed 6-hydroxychromanol derivate SUL-109 was shown to provide protection during hypothermic storage of several …
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