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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1968 2
1969 4
1970 2
1971 4
1972 11
1973 17
1974 3
1975 15
1976 8
1977 10
1978 14
1979 14
1980 24
1981 26
1982 41
1983 31
1984 32
1985 28
1986 22
1987 34
1988 23
1989 28
1990 34
1991 19
1992 35
1993 25
1994 24
1995 39
1996 21
1997 11
1998 21
1999 24
2000 14
2001 24
2002 10
2003 8
2004 7
2005 22
2006 12
2007 22
2008 20
2009 17
2010 17
2011 14
2012 16
2013 21
2014 34
2015 30
2016 27
2017 31
2018 20
2019 21
2020 19
2021 21
2022 19
2023 21
2024 28
2025 16

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1,111 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Trimethoprim-sulfamethoxazole significantly reduces the risk of nocardiosis in solid organ transplant recipients: systematic review and individual patient data meta-analysis.
Passerini M, Nayfeh T, Yetmar ZA, Coussement J, Goodlet KJ, Lebeaux D, Gori A, Mahmood M, Temesgen Z, Murad MH. Passerini M, et al. Clin Microbiol Infect. 2024 Feb;30(2):170-177. doi: 10.1016/j.cmi.2023.10.008. Epub 2023 Oct 19. Clin Microbiol Infect. 2024. PMID: 37865337 Free article.
BACKGROUND: Whether trimethoprim-sulfamethoxazole (TMP-SMX) prophylaxis prevents nocardiosis in solid organ transplant (SOT) recipients is controversial. ...
BACKGROUND: Whether trimethoprim-sulfamethoxazole (TMP-SMX) prophylaxis prevents nocardiosis in solid organ transplant (SOT) recipien …
Human Leukocyte Antigens and Sulfamethoxazole/Cotrimoxazole-Induced Severe Cutaneous Adverse Reactions: A Systematic Review and Meta-Analysis.
Wu PC, Chen WT, Huang IH, Chen CB, Wang CW, Tai CC, Chung WH, Chi CC. Wu PC, et al. JAMA Dermatol. 2024 May 1;160(5):525-534. doi: 10.1001/jamadermatol.2024.0210. JAMA Dermatol. 2024. PMID: 38568509 Free PMC article.
IMPORTANCE: Sulfamethoxazole (SMX) and cotrimoxazole (CTX), a fixed-dose combination of SMX and trimethoprim in a 5:1 ratio, are antibacterial sulfonamides commonly used for treating various diseases. ...
IMPORTANCE: Sulfamethoxazole (SMX) and cotrimoxazole (CTX), a fixed-dose combination of SMX and trimethoprim in a 5:1 ratio, are anti …
Meta-analysis of echinocandins combined with trimethoprim-sulfamethoxazole for treatment of Pneumocystis pneumonia.
Guo J, Chen Z, Kong C, Yu B, Wang T, Zhang Y, Liu Y, Zhou J, Qiu T. Guo J, et al. J Chemother. 2023 May;35(3):181-187. doi: 10.1080/1120009X.2022.2095155. Epub 2022 Jul 9. J Chemother. 2023. PMID: 35815561 Review.
The objective of this study was to review the all-cause mortality and efficacy of echinocandins combined with trimethoprim/sulfamethoxazole (TMP/SMZ) for the treatment of PCP. A meta-analysis of retrospective case-control studies of echinocandins combined with TMP/SMZ or T …
The objective of this study was to review the all-cause mortality and efficacy of echinocandins combined with trimethoprim/sulfamethoxazo …
Safety of sulfamethoxazole-trimethoprim for the treatment of bacterial infection in outpatient settings: A systematic review and meta-analysis with active comparator disproportionality analysis.
Preyra R, Eddin LE, Ahmadi F, Jafari A, Muanda FT. Preyra R, et al. Br J Clin Pharmacol. 2025 Jun;91(6):1632-1648. doi: 10.1111/bcp.70051. Br J Clin Pharmacol. 2025. PMID: 40441678 Free PMC article.
AIMS: Sulfamethoxazole-trimethoprim (SMX-TMP) is a widely used antibiotic for treating bacterial infections, but its safety in adult outpatients remains understudied. ...
AIMS: Sulfamethoxazole-trimethoprim (SMX-TMP) is a widely used antibiotic for treating bacterial infections, but its safety in adult …
Prophylaxis for Pneumocystis pneumonia (PCP) in non-HIV immunocompromised patients.
Stern A, Green H, Paul M, Vidal L, Leibovici L. Stern A, et al. Cochrane Database Syst Rev. 2014 Oct 1;2014(10):CD005590. doi: 10.1002/14651858.CD005590.pub3. Cochrane Database Syst Rev. 2014. PMID: 25269391 Free PMC article. Review.
No significant differences in overall adverse events or events requiring discontinuation were seen comparing trimethoprim/sulfamethoxazole to no treatment or placebo (four trials, 470 patients, moderate quality evidence). No differences between once daily versus thrice wee …
No significant differences in overall adverse events or events requiring discontinuation were seen comparing trimethoprim/sulfamethoxazol …
Alterations of human skin microbiome and expansion of antimicrobial resistance after systemic antibiotics.
Jo JH, Harkins CP, Schwardt NH, Portillo JA; NISC Comparative Sequencing Program; Zimmerman MD, Carter CL, Hossen MA, Peer CJ, Polley EC, Dartois V, Figg WD, Moutsopoulos NM, Segre JA, Kong HH. Jo JH, et al. Sci Transl Med. 2021 Dec 22;13(625):eabd8077. doi: 10.1126/scitranslmed.abd8077. Epub 2021 Dec 22. Sci Transl Med. 2021. PMID: 34936382 Free PMC article. Clinical Trial.
In a prospective, randomized study of four clinically relevant antibiotic regimens [doxycycline (20 mg or 100 mg), cephalexin, or trimethoprim/sulfamethoxazole], we investigated microbial alterations on skin after administration of systemic antibiotics to healthy human vol …
In a prospective, randomized study of four clinically relevant antibiotic regimens [doxycycline (20 mg or 100 mg), cephalexin, or trimethopr …
Safety of sulfamethoxazole-trimethoprim for the treatment of bacterial infection in outpatient settings: A systematic review and meta-analysis with active comparator disproportionality analysis.
Preyra R, Eddin LE, Ahmadi F, Jafari A, Muanda FT. Preyra R, et al. Br J Clin Pharmacol. 2025 Jun;91(6):1632-1648. doi: 10.1002/bcp.70051. Epub 2025 Mar 24. Br J Clin Pharmacol. 2025. PMID: 40129122 Review.
AIMS: Sulfamethoxazole-trimethoprim (SMX-TMP) is a widely used antibiotic for treating bacterial infections, but its safety in adult outpatients remains understudied. ...
AIMS: Sulfamethoxazole-trimethoprim (SMX-TMP) is a widely used antibiotic for treating bacterial infections, but its safety in adult …
Trimethoprim-sulfamethoxazole therapy for shigellosis.
Nelson JD, Kusmiesz H, Jackson LH, Woodman E. Nelson JD, et al. JAMA. 1976 Mar 22;235(12):1239-43. JAMA. 1976. PMID: 765518 Clinical Trial.
Twenty-eight infants and children hospitalized for severe shigellosis were treated orally either with ampicillin trihydrate (100 mg/kg/day administered in divided doses every six hours) or with trimethoprim-sulfamethoxazole (trimethoprim, 10 mg; sulfamethoxazole, 50 …
Twenty-eight infants and children hospitalized for severe shigellosis were treated orally either with ampicillin trihydrate (100 mg/kg/day a …
The role of trimethoprim/sulfamethoxazole in preventing opportunistic infections in systemic lupus erythematosus patients receiving low-level immunosuppressive treatment: an open-label, randomized, controlled trial.
Munthananuchat P, Ngamjanyaporn P, Pisitkun P, Rotjanapan P. Munthananuchat P, et al. Clin Exp Med. 2024 Oct 19;24(1):241. doi: 10.1007/s10238-024-01503-z. Clin Exp Med. 2024. PMID: 39425800 Free PMC article. Clinical Trial.
This study aimed to evaluate the effectiveness of trimethoprim/sulfamethoxazole (TMP/SMX) as primary prophylaxis against OIs and its adverse effects in SLE patients receiving low-level immunosuppressive treatment in a real-world setting. ...
This study aimed to evaluate the effectiveness of trimethoprim/sulfamethoxazole (TMP/SMX) as primary prophylaxis against OIs and its …
Trimethoprim-Sulfamethoxazole versus Placebo for Uncomplicated Skin Abscess.
Talan DA, Mower WR, Krishnadasan A, Abrahamian FM, Lovecchio F, Karras DJ, Steele MT, Rothman RE, Hoagland R, Moran GJ. Talan DA, et al. N Engl J Med. 2016 Mar 3;374(9):823-32. doi: 10.1056/NEJMoa1507476. N Engl J Med. 2016. PMID: 26962903 Free PMC article. Clinical Trial.
Trimethoprim-sulfamethoxazole was associated with slightly more gastrointestinal side effects (mostly mild) than placebo. At 7 to 14 days after the treatment period, invasive infections had developed in 2 of 524 participants (0.4%) in the trimethoprim-sulfamethoxazole …
Trimethoprim-sulfamethoxazole was associated with slightly more gastrointestinal side effects (mostly mild) than placebo. At 7 to 14 …
1,111 results