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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 1
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2011 5
2012 6
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2014 7
2015 10
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77 results

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Filters applied: Clinical Trial. Clear all
Page 1
Sulforaphane treatment of autism spectrum disorder (ASD).
Singh K, Connors SL, Macklin EA, Smith KD, Fahey JW, Talalay P, Zimmerman AW. Singh K, et al. Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15550-5. doi: 10.1073/pnas.1416940111. Epub 2014 Oct 13. Proc Natl Acad Sci U S A. 2014. PMID: 25313065 Free PMC article. Clinical Trial.
Initial scores for ABC and SRS were closely matched for participants assigned to placebo and sulforaphane. After 18 wk, participants receiving placebo experienced minimal change (<3.3%), whereas those receiving sulforaphane showed substantial declines (improvemen …
Initial scores for ABC and SRS were closely matched for participants assigned to placebo and sulforaphane. After 18 wk, participants …
Sulforaphane Treatment in Children with Autism: A Prospective Randomized Double-Blind Study.
Magner M, Thorová K, Župová V, Houška M, Švandová I, Novotná P, Tříska J, Vrchotová N, Soural I, Jílek L. Magner M, et al. Nutrients. 2023 Jan 31;15(3):718. doi: 10.3390/nu15030718. Nutrients. 2023. PMID: 36771424 Free PMC article. Clinical Trial.
Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder with repetitive behaviour which affects interaction and communication. Sulforaphane (SFN), an isothiocyanate abundant in the seeds and sprouts of cruciferous vegetables, has been shown to be effectiv …
Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder with repetitive behaviour which affects interaction and communicat …
Accumulation of Sulforaphane and Alliin in Human Prostate Tissue.
Livingstone TL, Saha S, Bernuzzi F, Savva GM, Troncoso-Rey P, Traka MH, Mills RD, Ball RY, Mithen RF. Livingstone TL, et al. Nutrients. 2022 Aug 10;14(16):3263. doi: 10.3390/nu14163263. Nutrients. 2022. PMID: 36014767 Free PMC article. Clinical Trial.
Following the intervention, prostate biopsy tissue was analysed for the presence of sulforaphane and its thiol conjugates and for alliin and associated metabolites. Sulforaphane occurred in significantly higher levels in the prostate tissue (both within the transiti …
Following the intervention, prostate biopsy tissue was analysed for the presence of sulforaphane and its thiol conjugates and for all …
Sulforaphane Bioavailability and Chemopreventive Activity in Men Presenting for Biopsy of the Prostate Gland: A Randomized Controlled Trial.
Zhang Z, Garzotto M, Davis EW 2nd, Mori M, Stoller WA, Farris PE, Wong CP, Beaver LM, Thomas GV, Williams DE, Dashwood RH, Hendrix DA, Ho E, Shannon J. Zhang Z, et al. Nutr Cancer. 2020;72(1):74-87. doi: 10.1080/01635581.2019.1619783. Epub 2019 Jun 1. Nutr Cancer. 2020. PMID: 31155953 Free PMC article. Clinical Trial.
Previous studies suggest compounds such as sulforaphane (SFN) derived from cruciferous vegetables may prevent prostate cancer development and progression. ...
Previous studies suggest compounds such as sulforaphane (SFN) derived from cruciferous vegetables may prevent prostate cancer develop …
Sulforaphane Bioavailability and Effects on Blood Pressure in Women with Pregnancy Hypertension.
Langston-Cox AG, Anderson D, Creek DJ, Palmer KR, Marshall SA, Wallace EM. Langston-Cox AG, et al. Reprod Sci. 2021 May;28(5):1489-1497. doi: 10.1007/s43032-020-00439-5. Epub 2021 Jan 6. Reprod Sci. 2021. PMID: 33409874 Clinical Trial.
Sulforaphane, an isothiocyanate found in cruciferous vegetables such as broccoli, shows promise as an adjuvant therapy for preeclampsia. ...Sulforaphane may improve endothelial function and blood pressure in women with pregnancy hypertension....
Sulforaphane, an isothiocyanate found in cruciferous vegetables such as broccoli, shows promise as an adjuvant therapy for preeclamps
Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder.
Zimmerman AW, Singh K, Connors SL, Liu H, Panjwani AA, Lee LC, Diggins E, Foley A, Melnyk S, Singh IN, James SJ, Frye RE, Fahey JW. Zimmerman AW, et al. Mol Autism. 2021 May 25;12(1):38. doi: 10.1186/s13229-021-00447-5. Mol Autism. 2021. PMID: 34034808 Free PMC article. Clinical Trial.
BACKGROUND: Sulforaphane (SF), an isothiocyanate in broccoli, has potential benefits relevant to autism spectrum disorder (ASD) through its effects on several metabolic and immunologic pathways. ...
BACKGROUND: Sulforaphane (SF), an isothiocyanate in broccoli, has potential benefits relevant to autism spectrum disorder (ASD) throu …
Efficacy of Sulforaphane in Treatment of Children with Autism Spectrum Disorder: A Randomized Double-Blind Placebo-Controlled Multi-center Trial.
Ou J, Smith RC, Tobe RH, Lin J, Arriaza J, Fahey JW, Liu R, Zeng Y, Liu Y, Huang L, Shen Y, Li Y, Cheng D, Cornblatt B, Davis JM, Zhao J, Wu R, Jin H. Ou J, et al. J Autism Dev Disord. 2024 Feb;54(2):628-641. doi: 10.1007/s10803-022-05784-9. Epub 2022 Nov 24. J Autism Dev Disord. 2024. PMID: 36427174 Clinical Trial.
Sulforaphane has been reported to possibly improve core symptoms associated with autism spectrum disorders from mostly small size studies. ...The effects of sulforaphane were seen across the full range of intelligence and greater in participants over 10 years. ...
Sulforaphane has been reported to possibly improve core symptoms associated with autism spectrum disorders from mostly small size stu
Sulforaphane improves the bronchoprotective response in asthmatics through Nrf2-mediated gene pathways.
Brown RH, Reynolds C, Brooker A, Talalay P, Fahey JW. Brown RH, et al. Respir Res. 2015 Sep 15;16(1):106. doi: 10.1186/s12931-015-0253-z. Respir Res. 2015. PMID: 26369337 Free PMC article. Clinical Trial.
Interestingly, in 20 % of the asthmatics, sulforaphane aggravated the bronchoconstrictor effects of MCh and in a similar number was without effect, documenting the great heterogeneity of the responsiveness of these individuals to sulforaphane. Moreover, in individua …
Interestingly, in 20 % of the asthmatics, sulforaphane aggravated the bronchoconstrictor effects of MCh and in a similar number was w …
Bioavailability of Glucoraphanin and Sulforaphane from High-Glucoraphanin Broccoli.
Sivapalan T, Melchini A, Saha S, Needs PW, Traka MH, Tapp H, Dainty JR, Mithen RF. Sivapalan T, et al. Mol Nutr Food Res. 2018 Sep;62(18):e1700911. doi: 10.1002/mnfr.201700911. Epub 2018 Mar 8. Mol Nutr Food Res. 2018. PMID: 29266773 Free PMC article. Clinical Trial.
This study seeks to quantify the exposure of human tissues to glucoraphanin and sulforaphane following consumption of broccoli with contrasting Myb28 genotypes. ...CONCLUSION: This is the first study to report the bioavailability of glucoraphanin and sulforaphane fr …
This study seeks to quantify the exposure of human tissues to glucoraphanin and sulforaphane following consumption of broccoli with c …
Sulforaphane as an adjunctive treatment for irritability in children with autism spectrum disorder: A randomized, double-blind, placebo-controlled clinical trial.
Momtazmanesh S, Amirimoghaddam-Yazdi Z, Moghaddam HS, Mohammadi MR, Akhondzadeh S. Momtazmanesh S, et al. Psychiatry Clin Neurosci. 2020 Jul;74(7):398-405. doi: 10.1111/pcn.13016. Epub 2020 May 26. Psychiatry Clin Neurosci. 2020. PMID: 32347624 Free article. Clinical Trial.
In this randomized, double-blind, placebo-controlled clinical trial, we aimed to investigate the beneficial effects of adjuvant treatment with risperidone and sulforaphane in alleviating the irritability of children with ASD. METHODS: Sixty drug-free patients aged 4-12 yea …
In this randomized, double-blind, placebo-controlled clinical trial, we aimed to investigate the beneficial effects of adjuvant treatment wi …
77 results