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Isothiocyanate from Broccoli, Sulforaphane, and Its Properties.
Vanduchova A, Anzenbacher P, Anzenbacherova E. Vanduchova A, et al. J Med Food. 2019 Feb;22(2):121-126. doi: 10.1089/jmf.2018.0024. Epub 2018 Oct 27. J Med Food. 2019. PMID: 30372361 Review.
Glucoraphanin requires the plant enzyme myrosinase for converting it into sulforaphane. Sulforaphane is metabolized through mercapturic acid pathway, being conjugated with glutathione and undergoes further biotransformation, yielding metabolites. Sulforaphane …
Glucoraphanin requires the plant enzyme myrosinase for converting it into sulforaphane. Sulforaphane is metabolized through me …
Efficacy of Sulforaphane in Neurodegenerative Diseases.
Schepici G, Bramanti P, Mazzon E. Schepici G, et al. Int J Mol Sci. 2020 Nov 16;21(22):8637. doi: 10.3390/ijms21228637. Int J Mol Sci. 2020. PMID: 33207780 Free PMC article. Review.
Sulforaphane (SFN) is a phytocompound belonging to the isothiocyanate family. Although it was also found in seeds and mature plants, SFN is mainly present in sprouts of many cruciferous vegetables, including cabbage, broccoli, cauliflower, and Brussels sprouts. ...
Sulforaphane (SFN) is a phytocompound belonging to the isothiocyanate family. Although it was also found in seeds and mature plants, …
Sulforaphane's Multifaceted Potential: From Neuroprotection to Anticancer Action.
Otoo RA, Allen AR. Otoo RA, et al. Molecules. 2023 Oct 1;28(19):6902. doi: 10.3390/molecules28196902. Molecules. 2023. PMID: 37836745 Free PMC article. Review.
Sulforaphane (SFN) is a naturally occurring compound found in cruciferous vegetables such as broccoli and cauliflower. ...
Sulforaphane (SFN) is a naturally occurring compound found in cruciferous vegetables such as broccoli and cauliflower. ...
Sulforaphane-driven reprogramming of gut microbiome and metabolome ameliorates the progression of hyperuricemia.
Wang R, Halimulati M, Huang X, Ma Y, Li L, Zhang Z. Wang R, et al. J Adv Res. 2023 Oct;52:19-28. doi: 10.1016/j.jare.2022.11.003. Epub 2022 Nov 10. J Adv Res. 2023. PMID: 36371056 Free PMC article.
RESULTS: Sulforaphane could lower uric acid by decreasing urate synthesis and increasing renal urate excretion in hyperuricemic rats (P<0.05). ...CONCLUSION: We revealed that sulforaphane could ameliorate the progression of hyperuricemia by reprogramming the gut …
RESULTS: Sulforaphane could lower uric acid by decreasing urate synthesis and increasing renal urate excretion in hyperuricemic rats …
Sulforaphane treatment of autism spectrum disorder (ASD).
Singh K, Connors SL, Macklin EA, Smith KD, Fahey JW, Talalay P, Zimmerman AW. Singh K, et al. Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15550-5. doi: 10.1073/pnas.1416940111. Epub 2014 Oct 13. Proc Natl Acad Sci U S A. 2014. PMID: 25313065 Free PMC article. Clinical Trial.
Initial scores for ABC and SRS were closely matched for participants assigned to placebo and sulforaphane. After 18 wk, participants receiving placebo experienced minimal change (<3.3%), whereas those receiving sulforaphane showed substantial declines (improvemen …
Initial scores for ABC and SRS were closely matched for participants assigned to placebo and sulforaphane. After 18 wk, participants …
Sulforaphane promotes C. elegans longevity and healthspan via DAF-16/DAF-2 insulin/IGF-1 signaling.
Qi Z, Ji H, Le M, Li H, Wieland A, Bauer S, Liu L, Wink M, Herr I. Qi Z, et al. Aging (Albany NY). 2021 Jan 20;13(2):1649-1670. doi: 10.18632/aging.202512. Epub 2021 Jan 20. Aging (Albany NY). 2021. PMID: 33471780 Free PMC article.
The broccoli-derived isothiocyanate sulforaphane inhibits inflammation, oxidative stress and cancer, but its effect on healthspan and longevity are unclear. ...Our results provide the basis for a nutritional sulforaphane-enriched strategy for the promotion of health …
The broccoli-derived isothiocyanate sulforaphane inhibits inflammation, oxidative stress and cancer, but its effect on healthspan and …
Sulforaphane and Its Protective Role in Prostate Cancer: A Mechanistic Approach.
Mordecai J, Ullah S, Ahmad I. Mordecai J, et al. Int J Mol Sci. 2023 Apr 10;24(8):6979. doi: 10.3390/ijms24086979. Int J Mol Sci. 2023. PMID: 37108142 Free PMC article. Review.
Numerous studies have shown that sulforaphane prevents the development and progression of prostatic tumors. This review evaluates the most recent published reports on prevention of the progression of prostate cancer by sulforaphane in vitro, in vivo and in clinical …
Numerous studies have shown that sulforaphane prevents the development and progression of prostatic tumors. This review evaluates the …
Exploring the anti-inflammatory activity of sulforaphane.
Treasure K, Harris J, Williamson G. Treasure K, et al. Immunol Cell Biol. 2023 Oct;101(9):805-828. doi: 10.1111/imcb.12686. Epub 2023 Aug 31. Immunol Cell Biol. 2023. PMID: 37650498 Review.
Moreover, a growing body of evidence suggests additional diverse anti-inflammatory properties of sulforaphane through interactions with mediators of key signaling pathways and inflammatory cytokines. ...Significantly, studies have also highlighted potential steroid-sparing …
Moreover, a growing body of evidence suggests additional diverse anti-inflammatory properties of sulforaphane through interactions wi …
Sulforaphane as a potential remedy against cancer: Comprehensive mechanistic review.
Iahtisham-Ul-Haq, Khan S, Awan KA, Iqbal MJ. Iahtisham-Ul-Haq, et al. J Food Biochem. 2022 Mar;46(3):e13886. doi: 10.1111/jfbc.13886. Epub 2021 Aug 5. J Food Biochem. 2022. PMID: 34350614 Review.
Sulforaphane belongs to the active class of isothiocyanates capable of delivering various biological benefits for health promotion and disease prevention. ...This article provides sufficient evidence via discussing the underlying mechanisms of positive effects of sulfor …
Sulforaphane belongs to the active class of isothiocyanates capable of delivering various biological benefits for health promotion an …
Sulforaphane and Its Bifunctional Analogs: Synthesis and Biological Activity.
Janczewski Ł. Janczewski Ł. Molecules. 2022 Mar 7;27(5):1750. doi: 10.3390/molecules27051750. Molecules. 2022. PMID: 35268851 Free PMC article. Review.
Natural isothiocyanates, such as benzyl isothiocyanate, phenethyl isothiocyanate, or the best-tested sulforaphane, possess anticancer activity at all stages of the carcinogenesis process, show antibacterial activity, and are used in organic synthesis. Methods of synthesis …
Natural isothiocyanates, such as benzyl isothiocyanate, phenethyl isothiocyanate, or the best-tested sulforaphane, possess anticancer …
3,302 results

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