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Page 1
Isothiocyanate from Broccoli, Sulforaphane, and Its Properties.
Vanduchova A, Anzenbacher P, Anzenbacherova E. Vanduchova A, et al. J Med Food. 2019 Feb;22(2):121-126. doi: 10.1089/jmf.2018.0024. Epub 2018 Oct 27. J Med Food. 2019. PMID: 30372361 Review.
Glucoraphanin requires the plant enzyme myrosinase for converting it into sulforaphane. Sulforaphane is metabolized through mercapturic acid pathway, being conjugated with glutathione and undergoes further biotransformation, yielding metabolites. Sulforaphane
Glucoraphanin requires the plant enzyme myrosinase for converting it into sulforaphane. Sulforaphane is metabolized through me …
Efficacy of Sulforaphane in Neurodegenerative Diseases.
Schepici G, Bramanti P, Mazzon E. Schepici G, et al. Int J Mol Sci. 2020 Nov 16;21(22):8637. doi: 10.3390/ijms21228637. Int J Mol Sci. 2020. PMID: 33207780 Free PMC article. Review.
Sulforaphane (SFN) is a phytocompound belonging to the isothiocyanate family. ...
Sulforaphane (SFN) is a phytocompound belonging to the isothiocyanate family. ...
Nrf2 targeting by sulforaphane: A potential therapy for cancer treatment.
Russo M, Spagnuolo C, Russo GL, Skalicka-Woźniak K, Daglia M, Sobarzo-Sánchez E, Nabavi SF, Nabavi SM. Russo M, et al. Crit Rev Food Sci Nutr. 2018 May 24;58(8):1391-1405. doi: 10.1080/10408398.2016.1259983. Epub 2017 Jul 21. Crit Rev Food Sci Nutr. 2018. PMID: 28001083 Review.
Sulforaphane was found to be active against several forms of cancer. ...At molecular level, sulforaphane modulates cellular homeostasis via the activation of the transcription factor Nrf2. ...
Sulforaphane was found to be active against several forms of cancer. ...At molecular level, sulforaphane modulates cellular ho
Sulforaphane promotes C. elegans longevity and healthspan via DAF-16/DAF-2 insulin/IGF-1 signaling.
Qi Z, Ji H, Le M, Li H, Wieland A, Bauer S, Liu L, Wink M, Herr I. Qi Z, et al. Aging (Albany NY). 2021 Jan 20;13(2):1649-1670. doi: 10.18632/aging.202512. Epub 2021 Jan 20. Aging (Albany NY). 2021. PMID: 33471780 Free PMC article.
The broccoli-derived isothiocyanate sulforaphane inhibits inflammation, oxidative stress and cancer, but its effect on healthspan and longevity are unclear. ...Our results provide the basis for a nutritional sulforaphane-enriched strategy for the promotion of health …
The broccoli-derived isothiocyanate sulforaphane inhibits inflammation, oxidative stress and cancer, but its effect on healthspan and …
Sulforaphane treatment of autism spectrum disorder (ASD).
Singh K, Connors SL, Macklin EA, Smith KD, Fahey JW, Talalay P, Zimmerman AW. Singh K, et al. Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15550-5. doi: 10.1073/pnas.1416940111. Epub 2014 Oct 13. Proc Natl Acad Sci U S A. 2014. PMID: 25313065 Free PMC article. Clinical Trial.
Initial scores for ABC and SRS were closely matched for participants assigned to placebo and sulforaphane. After 18 wk, participants receiving placebo experienced minimal change (<3.3%), whereas those receiving sulforaphane showed substantial declines (improvemen …
Initial scores for ABC and SRS were closely matched for participants assigned to placebo and sulforaphane. After 18 wk, participants …
Sulforaphane as a potential remedy against cancer: Comprehensive mechanistic review.
Iahtisham-Ul-Haq, Khan S, Awan KA, Iqbal MJ. Iahtisham-Ul-Haq, et al. J Food Biochem. 2022 Mar;46(3):e13886. doi: 10.1111/jfbc.13886. Epub 2021 Aug 5. J Food Biochem. 2022. PMID: 34350614 Review.
Sulforaphane belongs to the active class of isothiocyanates capable of delivering various biological benefits for health promotion and disease prevention. ...This article provides sufficient evidence via discussing the underlying mechanisms of positive effects of sulfor
Sulforaphane belongs to the active class of isothiocyanates capable of delivering various biological benefits for health promotion an
Sulforaphane and Its Bifunctional Analogs: Synthesis and Biological Activity.
Janczewski Ł. Janczewski Ł. Molecules. 2022 Mar 7;27(5):1750. doi: 10.3390/molecules27051750. Molecules. 2022. PMID: 35268851 Free PMC article. Review.
Natural isothiocyanates, such as benzyl isothiocyanate, phenethyl isothiocyanate, or the best-tested sulforaphane, possess anticancer activity at all stages of the carcinogenesis process, show antibacterial activity, and are used in organic synthesis. Methods of synthesis …
Natural isothiocyanates, such as benzyl isothiocyanate, phenethyl isothiocyanate, or the best-tested sulforaphane, possess anticancer …
Use of sulforaphane in COVID-19: Clinical trials are needed.
Kow CS, Ramachandram DS, Hasan SS. Kow CS, et al. Mol Immunol. 2022 May;145:78-79. doi: 10.1016/j.molimm.2022.03.001. Epub 2022 Mar 7. Mol Immunol. 2022. PMID: 35303531 Free PMC article. Review.
We read with interest the narrative review authored by Kiser et al. (2021), which discussed extensively the antioxidant effect and anti-inflammatory effect of sulforaphane, a dietary supplement found in high amounts in cruciferous vegetables that ais orally accessible and …
We read with interest the narrative review authored by Kiser et al. (2021), which discussed extensively the antioxidant effect and anti-infl …
Sulforaphane and Its Protective Role in Prostate Cancer: A Mechanistic Approach.
Mordecai J, Ullah S, Ahmad I. Mordecai J, et al. Int J Mol Sci. 2023 Apr 10;24(8):6979. doi: 10.3390/ijms24086979. Int J Mol Sci. 2023. PMID: 37108142 Free PMC article. Review.
Numerous studies have shown that sulforaphane prevents the development and progression of prostatic tumors. This review evaluates the most recent published reports on prevention of the progression of prostate cancer by sulforaphane in vitro, in vivo and in clinical …
Numerous studies have shown that sulforaphane prevents the development and progression of prostatic tumors. This review evaluates the …
Sulforaphane Impact on Reactive Oxygen Species (ROS) in Bladder Carcinoma.
Xie H, Chun FK, Rutz J, Blaheta RA. Xie H, et al. Int J Mol Sci. 2021 May 31;22(11):5938. doi: 10.3390/ijms22115938. Int J Mol Sci. 2021. PMID: 34073079 Free PMC article. Review.
Sulforaphane (SFN) is a natural glucosinolate found in cruciferous vegetables that acts as a chemopreventive agent, but its mechanism of action is not clear. ...
Sulforaphane (SFN) is a natural glucosinolate found in cruciferous vegetables that acts as a chemopreventive agent, but its mechanism
2,973 results