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Page 1
Sulforaphane treatment for autism spectrum disorder: A systematic review.
McGuinness G, Kim Y. McGuinness G, et al. EXCLI J. 2020 Jun 26;19:892-903. doi: 10.17179/excli2020-2487. eCollection 2020. EXCLI J. 2020. PMID: 33013262 Free PMC article. Review.
Autism Spectrum Disorder (ASD) is defined as a neurodevelopmental condition characterized by social communication impairment, delayed development, social function deficit, and repetitive behaviors. ...This systematic review evaluated the use of sulforaphane ( …
Autism Spectrum Disorder (ASD) is defined as a neurodevelopmental condition characterized by social communication impairment, …
Isothiocyanate from Broccoli, Sulforaphane, and Its Properties.
Vanduchova A, Anzenbacher P, Anzenbacherova E. Vanduchova A, et al. J Med Food. 2019 Feb;22(2):121-126. doi: 10.1089/jmf.2018.0024. Epub 2018 Oct 27. J Med Food. 2019. PMID: 30372361 Review.
Sulforaphane is extensively investigated and is in the interest in medicine for its health benefits. It has been shown that sulforaphane may protect against various types of cancer, may also decrease the risk of cardiovascular disease, and help in autism and …
Sulforaphane is extensively investigated and is in the interest in medicine for its health benefits. It has been shown that sulfor …
The effect of sulforaphane on autism spectrum disorder: systematic review and meta-analysis.
Wang R, Ren Z, Li Y. Wang R, et al. EXCLI J. 2025 Apr 7;24:542-557. doi: 10.17179/excli2025-8239. eCollection 2025. EXCLI J. 2025. PMID: 40458076 Free PMC article. Review.
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder lacking effective treatments. This systematic review and meta-analysis assesses the efficacy and safety of sulforaphane (SFN) for ASD. Eight databases were searched from inception …
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder lacking effective treatments. This systematic r …
Pharmacological and dietary-supplement treatments for autism spectrum disorder: a systematic review and network meta-analysis.
Siafis S, Çıray O, Wu H, Schneider-Thoma J, Bighelli I, Krause M, Rodolico A, Ceraso A, Deste G, Huhn M, Fraguas D, San José Cáceres A, Mavridis D, Charman T, Murphy DG, Parellada M, Arango C, Leucht S. Siafis S, et al. Mol Autism. 2022 Mar 4;13(1):10. doi: 10.1186/s13229-022-00488-4. Mol Autism. 2022. PMID: 35246237 Free PMC article.
BACKGROUND: There is still no approved medication for the core symptoms of autism spectrum disorder (ASD). This network meta-analysis investigated pharmacological and dietary-supplement treatments for ASD. ...Associated symptoms, e.g., irritability/aggression and at …
BACKGROUND: There is still no approved medication for the core symptoms of autism spectrum disorder (ASD). This network meta-a …
Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder.
Zimmerman AW, Singh K, Connors SL, Liu H, Panjwani AA, Lee LC, Diggins E, Foley A, Melnyk S, Singh IN, James SJ, Frye RE, Fahey JW. Zimmerman AW, et al. Mol Autism. 2021 May 25;12(1):38. doi: 10.1186/s13229-021-00447-5. Mol Autism. 2021. PMID: 34034808 Free PMC article. Clinical Trial.
BACKGROUND: Sulforaphane (SF), an isothiocyanate in broccoli, has potential benefits relevant to autism spectrum disorder (ASD) through its effects on several metabolic and immunologic pathways. ...Treatment effects on the primary outcome measure, the Ohio …
BACKGROUND: Sulforaphane (SF), an isothiocyanate in broccoli, has potential benefits relevant to autism spectrum disorder …
Investigating the clinical efficacy, safety and molecular mechanism of sulforaphane in autism spectrum disorder: an integrated study combining meta-analysis, network pharmacology, and computational biology.
Long J, Liao X, Tang Z, Han K, Chen J, Wang X, Liu J, Zhang Y, Zhang H. Long J, et al. BMC Pharmacol Toxicol. 2025 Nov 22;26(1):217. doi: 10.1186/s40360-025-01052-5. BMC Pharmacol Toxicol. 2025. PMID: 41275316 Free PMC article.
BACKGROUND: Sulforaphane, a natural antioxidant rich in cruciferous vegetables, has emerged as a promising dietary supplement for autism spectrum disorder (ASD). ...GEO transcriptomic data provided independent validation for the network pharmacology predictio …
BACKGROUND: Sulforaphane, a natural antioxidant rich in cruciferous vegetables, has emerged as a promising dietary supplement for …
A Review on Autism Spectrum Disorder: Pathogenesis, Biomarkers, Pharmacological and Non-Pharmacological Interventions.
Majhi S, Kumar S, Singh L. Majhi S, et al. CNS Neurol Disord Drug Targets. 2023;22(5):659-677. doi: 10.2174/1871527321666220428134802. CNS Neurol Disord Drug Targets. 2023. PMID: 36915952 Review.
Autistic spectrum disorder (ASD) is a complicated developmental disease characterized by persistent difficulties in social interaction, speech and nonverbal communication, and restricted/ repetitive activities. ...This would significantly reduce the tally of people …
Autistic spectrum disorder (ASD) is a complicated developmental disease characterized by persistent difficulties in social int …
Sulforaphane Treatment in Children with Autism: A Prospective Randomized Double-Blind Study.
Magner M, Thorová K, Župová V, Houška M, Švandová I, Novotná P, Tříska J, Vrchotová N, Soural I, Jílek L. Magner M, et al. Nutrients. 2023 Jan 31;15(3):718. doi: 10.3390/nu15030718. Nutrients. 2023. PMID: 36771424 Free PMC article. Clinical Trial.
Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder with repetitive behaviour which affects interaction and communication. Sulforaphane (SFN), an isothiocyanate abundant in the seeds and sprouts of cruciferous vegetables, has been …
Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder with repetitive behaviour which affects inter …
Effects of sulforaphane on ABC and SRS scales in patients with autism spectrum disorder: a meta-analysis.
Guo J, Wang Y, He W, Lou M, Peng Y, Shi H, Lian A. Guo J, et al. Brain Dev. 2025 Apr;47(2):104321. doi: 10.1016/j.braindev.2025.104321. Epub 2025 Feb 14. Brain Dev. 2025. PMID: 39951914 Free article. Review.
Autism spectrum disorder (ASD) has become an increasingly prominent global health issue. ...The results of this meta-analysis showed that sulforaphane significantly improved irritability and hyperactivity symptoms, suggesting that sulforaphane has the …
Autism spectrum disorder (ASD) has become an increasingly prominent global health issue. ...The results of this meta-analysis …
Therapeutic efficacy of sulforaphane in autism spectrum disorders and its association with gut microbiota: animal model and human longitudinal studies.
Yang J, He L, Dai S, Zheng H, Cui X, Ou J, Zhang X. Yang J, et al. Front Nutr. 2024 Jan 8;10:1294057. doi: 10.3389/fnut.2023.1294057. eCollection 2023. Front Nutr. 2024. PMID: 38260076 Free PMC article.
INTRODUCTION: Sulforaphane (SFN) has been found to alleviate complications linked with several diseases by regulating gut microbiota (GM), while the effect of GM on SFN for autism spectrum disorders (ASD) has not been studied. ...METHODS: We evaluated the therapeuti …
INTRODUCTION: Sulforaphane (SFN) has been found to alleviate complications linked with several diseases by regulating gut microbiota …
65 results