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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 3
1995 1
1996 2
1997 1
1998 1
1999 2
2000 1
2002 5
2004 4
2005 3
2006 4
2007 1
2008 5
2009 1
2010 1
2011 1
2012 2
2013 1
2014 1
2016 5
2017 3
2018 3
2019 2
2020 3
2021 2
2022 0
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53 results
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Page 1
C. elegans Apical Extracellular Matrices Shape Epithelia.
Cohen JD, Sundaram MV. Cohen JD, et al. J Dev Biol. 2020 Oct 6;8(4):23. doi: 10.3390/jdb8040023. J Dev Biol. 2020. PMID: 33036165 Free PMC article. Review.
Despite their widespread importance for human health, aECMs are poorly understood compared to basal and stromal ECMs. The nematode Caenorhabditis elegans contains a variety of distinct aECMs, some of which share many of the same types of components (lipids, lipoproteins, c …
Despite their widespread importance for human health, aECMs are poorly understood compared to basal and stromal ECMs. The nematode Caenorhab …
The Gene Ontology resource: enriching a GOld mine.
Gene Ontology Consortium. Gene Ontology Consortium. Nucleic Acids Res. 2021 Jan 8;49(D1):D325-D334. doi: 10.1093/nar/gkaa1113. Nucleic Acids Res. 2021. PMID: 33290552 Free PMC article.
RTK/Ras/MAPK signaling.
Sundaram MV. Sundaram MV. WormBook. 2006 Feb 11:1-19. doi: 10.1895/wormbook.1.80.1. WormBook. 2006. PMID: 18050474 Free PMC article. Review.
Receptor Tyrosine Kinase (RTK)/Ras GTPase/MAP kinase (MAPK) signaling pathways are used repeatedly during metazoan development to control many different biological processes. In the nematode Caenorhabditis elegans, two different RTKs (LET-23/EGFR and EGL-15/FGFR) are known …
Receptor Tyrosine Kinase (RTK)/Ras GTPase/MAP kinase (MAPK) signaling pathways are used repeatedly during metazoan development to control ma …
The Caenorhabditis elegans Excretory System: A Model for Tubulogenesis, Cell Fate Specification, and Plasticity.
Sundaram MV, Buechner M. Sundaram MV, et al. Genetics. 2016 May;203(1):35-63. doi: 10.1534/genetics.116.189357. Genetics. 2016. PMID: 27183565 Free PMC article. Review.
The excretory system of the nematode Caenorhabditis elegans is a superb model of tubular organogenesis involving a minimum of cells. ...
The excretory system of the nematode Caenorhabditis elegans is a superb model of tubular organogenesis involving a minimum of cells. …
A C. elegans Zona Pellucida domain protein functions via its ZPc domain.
Cohen JD, Bermudez JG, Good MC, Sundaram MV. Cohen JD, et al. PLoS Genet. 2020 Nov 3;16(11):e1009188. doi: 10.1371/journal.pgen.1009188. eCollection 2020 Nov. PLoS Genet. 2020. PMID: 33141826 Free PMC article.
Current models suggest that ZP proteins polymerize via their ZPn subdomains, while ZPc subdomains modulate ZPn behavior. Using the model organism C. elegans, we investigated the aECM assembly of one ZP protein, LET-653, which shapes several tubes. ...
Current models suggest that ZP proteins polymerize via their ZPn subdomains, while ZPc subdomains modulate ZPn behavior. Using the model org …
The Caenorhabditis elegans Patched domain protein PTR-4 is required for proper organization of the precuticular apical extracellular matrix.
Cohen JD, Cadena Del Castillo CE, Serra ND, Kaech A, Spang A, Sundaram MV. Cohen JD, et al. Genetics. 2021 Nov 5;219(3):iyab132. doi: 10.1093/genetics/iyab132. Genetics. 2021. PMID: 34740248 Free article.
While the Hedgehog receptor Patched has been intensively studied, much less is known about the biological roles of other Patched-related family members. Caenorhabditis elegans has a large number of Patched-related proteins, despite lacking a canonical Hedgehog pathway. ...
While the Hedgehog receptor Patched has been intensively studied, much less is known about the biological roles of other Patched-related fam …
Auto-fusion and the shaping of neurons and tubes.
Soulavie F, Sundaram MV. Soulavie F, et al. Semin Cell Dev Biol. 2016 Dec;60:136-145. doi: 10.1016/j.semcdb.2016.07.018. Epub 2016 Jul 18. Semin Cell Dev Biol. 2016. PMID: 27436685 Free PMC article. Review.
In contrast to cell-cell fusion or macropinocytic fission, which result in the merging or formation of two separate membrane bound compartments, auto-fusion preserves one compartment, but changes its shape. The discovery of auto-fusion in C. elegans was enabled by identifi …
In contrast to cell-cell fusion or macropinocytic fission, which result in the merging or formation of two separate membrane bound compartme …
Lethargus is a Caenorhabditis elegans sleep-like state.
Raizen DM, Zimmerman JE, Maycock MH, Ta UD, You YJ, Sundaram MV, Pack AI. Raizen DM, et al. Nature. 2008 Jan 31;451(7178):569-72. doi: 10.1038/nature06535. Epub 2008 Jan 9. Nature. 2008. PMID: 18185515
We identify the cGMP-dependent protein kinase (PKG) gene egl-4 as a regulator of sleep-like behaviour, and show that egl-4 functions in sensory neurons to promote the C. elegans sleep-like state. Conserved effects on sleep-like behaviour of homologous genes in C. elegan
We identify the cGMP-dependent protein kinase (PKG) gene egl-4 as a regulator of sleep-like behaviour, and show that egl-4 functions in sens …
Epidermal Remodeling in Caenorhabditis elegans Dauers Requires the Nidogen Domain Protein DEX-1.
Flatt KM, Beshers C, Unal C, Cohen JD, Sundaram MV, Schroeder NE. Flatt KM, et al. Genetics. 2019 Jan;211(1):169-183. doi: 10.1534/genetics.118.301557. Epub 2018 Nov 8. Genetics. 2019. PMID: 30409788 Free PMC article.
Phenotypic plasticity is a critical component of an organism's ability to thrive in a changing environment. The free-living nematode Caenorhabditis elegans adapts to unfavorable environmental conditions by pausing reproductive development and entering a stress-resistant la …
Phenotypic plasticity is a critical component of an organism's ability to thrive in a changing environment. The free-living nematode Caenorh …
Canonical RTK-Ras-ERK signaling and related alternative pathways.
Sundaram MV. Sundaram MV. WormBook. 2013 Jul 11:1-38. doi: 10.1895/wormbook.1.80.2. WormBook. 2013. PMID: 23908058 Free PMC article. Review.
Receptor Tyrosine Kinase (RTK)-Ras-Extracellular signal-regulated kinase (ERK) signaling pathways control many aspects of C. elegans development and behavior. Studies in C. elegans helped elucidate the basic framework of the RTK-Ras-ERK pathway and continue to provi …
Receptor Tyrosine Kinase (RTK)-Ras-Extracellular signal-regulated kinase (ERK) signaling pathways control many aspects of C. elegans
53 results