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The global H5N1 influenza panzootic in mammals.
Peacock TP, Moncla L, Dudas G, VanInsberghe D, Sukhova K, Lloyd-Smith JO, Worobey M, Lowen AC, Nelson MI. Peacock TP, et al. Nature. 2025 Jan;637(8045):304-313. doi: 10.1038/s41586-024-08054-z. Epub 2024 Sep 24. Nature. 2025. PMID: 39317240 Review.
Influenza A viruses have caused more documented global pandemics in human history than any other pathogen(1,2). ...The virus has sustained mammal-to-mammal transmission in multiple settings, including European fur farms(10,11), South American marine mammals(12-15) a …
Influenza A viruses have caused more documented global pandemics in human history than any other pathogen(1,2). ...The virus h …
Pandemic preparedness through vaccine development for avian influenza viruses.
Cargnin Faccin F, Perez DR. Cargnin Faccin F, et al. Hum Vaccin Immunother. 2024 Dec 31;20(1):2347019. doi: 10.1080/21645515.2024.2347019. Epub 2024 May 28. Hum Vaccin Immunother. 2024. PMID: 38807261 Free PMC article. Review.
Influenza A viruses pose a significant threat to global health, impacting both humans and animals. Zoonotic transmission, particularly from swine and avian species, is the primary source of human influenza outbreaks. Notably, avian influenza vir …
Influenza A viruses pose a significant threat to global health, impacting both humans and animals. Zoonotic transmission, particularl …
Influenza Vaccines.
[No authors listed] [No authors listed] 2024 Aug 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2024 Aug 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000049 Free Books & Documents. Review.
The Centers for Disease Control and Prevention and several health professional organizations state that vaccines given to a nursing mother do not affect the safety of breastfeeding for mothers or infants and that breastfeeding is not a contraindication to either the live, attenua …
The Centers for Disease Control and Prevention and several health professional organizations state that vaccines given to a nursing mother d …
The panzootic spread of highly pathogenic avian influenza H5N1 sublineage 2.3.4.4b: a critical appraisal of One Health preparedness and prevention.
Koopmans MPG, Barton Behravesh C, Cunningham AA, Adisasmito WB, Almuhairi S, Bilivogui P, Bukachi SA, Casas N, Cediel Becerra N, Charron DF, Chaudhary A, Ciacci Zanella JR, Dar O, Debnath N, Dungu B, Farag E, Gao GF, Khaitsa M, Machalaba C, Mackenzie JS, Markotter W, Mettenleiter TC, Morand S, Smolenskiy V, Zhou L, Hayman DTS; One Health High-Level Expert Panel. Koopmans MPG, et al. Lancet Infect Dis. 2024 Dec;24(12):e774-e781. doi: 10.1016/S1473-3099(24)00438-9. Epub 2024 Aug 9. Lancet Infect Dis. 2024. PMID: 39134084 Review.
Changes in the epidemiology and ecology of H5N1 highly pathogenic avian influenza are devastating wild bird and poultry populations, farms and communities, and wild mammals worldwide. Having originated in farmed poultry, H5N1 viruses are now spread globally by wild birds, …
Changes in the epidemiology and ecology of H5N1 highly pathogenic avian influenza are devastating wild bird and poultry populations, …
MHC class II proteins mediate sialic acid independent entry of human and avian H2N2 influenza A viruses.
Karakus U, Sempere Borau M, Martínez-Barragán P, von Kempis J, Yildiz S, Arroyo-Fernández LM, Pohl MO, Steiger JA, Glas I, Hunziker A, García-Sastre A, Stertz S. Karakus U, et al. Nat Microbiol. 2024 Oct;9(10):2626-2641. doi: 10.1038/s41564-024-01771-1. Epub 2024 Jul 15. Nat Microbiol. 2024. PMID: 39009691
Influenza A viruses (IAV) pose substantial burden on human and animal health. Avian, swine and human IAV bind sialic acid on host glycans as receptor, whereas some bat IAV require MHC class II complexes for cell entry. It is unknown how this difference …
Influenza A viruses (IAV) pose substantial burden on human and animal health. Avian, swine and human IAV bind si …
Modular Nano-Antigen Display Platform for Pigs Induces Potent Immune Responses.
Chen Y, Zhu J, Wang S, Li M, Sun X, Liu S, Wang Y, Li R, Zhang G. Chen Y, et al. ACS Nano. 2024 Oct 22;18(42):29152-29177. doi: 10.1021/acsnano.4c10725. Epub 2024 Oct 10. ACS Nano. 2024. PMID: 39387806
The use of the platform demonstrates that HA antigen protects against lethal attacks by influenza viruses and reduces viral load in the lungs. We have demonstrated that the Cap-Cat VLPs platform demonstrates that antigens enhance the immune response by improving the proces …
The use of the platform demonstrates that HA antigen protects against lethal attacks by influenza viruses and reduces viral load in t …
Europe needs a sustainably funded influenza research and response network.
Krammer F, Barclay WS, Beer M, Brown IH, Cox RJ, de Jong MD, Fodor E, Fouchier RAM, Gabriel G, García-Sastre A, Guiomar R, Horby P, Koopmans M, Lewis NS, Maggi S, Monne I, Naffakh N, Nohynek H, Osterhaus A, Prosenc K, Prymula R, Rappuoli R, Redlberger-Fritz M, Rimmelzwaan GF, Russell CA, Saelens X, Schwemmle M, Smith DJ, Stertz S, Tähtinen PA, Terregino C, Thålin C. Krammer F, et al. Lancet Infect Dis. 2025 Apr;25(4):369-372. doi: 10.1016/S1473-3099(25)00068-4. Epub 2025 Feb 17. Lancet Infect Dis. 2025. PMID: 39978373 No abstract available.
Potential pandemic risk of circulating swine H1N2 influenza viruses.
Le Sage V, Rockey NC, French AJ, McBride R, McCarthy KR, Rigatti LH, Shephard MJ, Jones JE, Walter SG, Doyle JD, Xu L, Barbeau DJ, Wang S, Frizzell SA, Myerburg MM, Paulson JC, McElroy AK, Anderson TK, Vincent Baker AL, Lakdawala SS. Le Sage V, et al. Nat Commun. 2024 Jun 13;15(1):5025. doi: 10.1038/s41467-024-49117-z. Nat Commun. 2024. PMID: 38871701 Free PMC article.
Influenza A viruses in swine have considerable genetic diversity and continue to pose a pandemic threat to humans due to a potential lack of population level immunity. ...The alpha-swH1N2 virus replicates efficiently in human airway cultures and exhibits phen …
Influenza A viruses in swine have considerable genetic diversity and continue to pose a pandemic threat to humans due to a pot …
Gene editing of pigs to control influenza A virus infections.
Kwon T, Artiaga BL, McDowell CD, Whitworth KM, Wells KD, Prather RS, Delhon G, Cigan M, White SN, Retallick J, Gaudreault NN, Morozov I, Richt JA. Kwon T, et al. Emerg Microbes Infect. 2024 Dec;13(1):2387449. doi: 10.1080/22221751.2024.2387449. Epub 2024 Aug 24. Emerg Microbes Infect. 2024. PMID: 39083026 Free PMC article.
Proteolytic activation of the haemagglutinin (HA) glycoprotein by host cellular proteases is pivotal for influenza A virus (IAV) infectivity. Highly pathogenic avian influenza viruses possess the multibasic cleavage site of the HA which is cleaved by ubiquitous prot …
Proteolytic activation of the haemagglutinin (HA) glycoprotein by host cellular proteases is pivotal for influenza A virus (IAV) infe …
Influenza D virus infection in China, 2022-2023.
Yu J, Wen Z, Hu W, Chen M, Zhang Y, Liu S, Wang G, Wang Z, Wang D, Zhai SL, Wei WK, Li T, Liao M. Yu J, et al. Emerg Microbes Infect. 2024 Dec;13(1):2343907. doi: 10.1080/22221751.2024.2343907. Epub 2024 May 15. Emerg Microbes Infect. 2024. PMID: 38738553 Free PMC article.
Influenza D virus (IDV) plays an important role in the bovine respiratory disease (BRD) complex. ...Finally, the Chinese IDVs replicated robustly in diverse cell lines but less efficiently in the swine cell line. Considering the nationwide distribution, high seropre …
Influenza D virus (IDV) plays an important role in the bovine respiratory disease (BRD) complex. ...Finally, the Chinese IDVs replica …
205 results