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Post-infectious autoimmune disorders: Sydenham's chorea, PANDAS and beyond.
Williams KA, Swedo SE. Williams KA, et al. Brain Res. 2015 Aug 18;1617:144-54. doi: 10.1016/j.brainres.2014.09.071. Epub 2014 Oct 7. Brain Res. 2015. PMID: 25301689 Review.
Sydenham's chorea (SC), a widely recognized post-streptococcal autoimmune disorder, represents a model for this proposed pathogenesis. ...PANDAS (Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal infections) has been proposed as a v …
Sydenham's chorea (SC), a widely recognized post-streptococcal autoimmune disorder, represents a model for this proposed patho …
Autoimmune and paraneoplastic movement disorders: An update.
Baizabal-Carvallo JF, Jankovic J. Baizabal-Carvallo JF, et al. J Neurol Sci. 2018 Feb 15;385:175-184. doi: 10.1016/j.jns.2017.12.035. Epub 2017 Dec 30. J Neurol Sci. 2018. PMID: 29406902 Review.
They may be observed in autoimmune disorders triggered by an infectious agent, such as streptococcus in Sydenham's chorea, or in basal ganglia encephalitis with antibodies against the dopamine-D2 receptors. ...Autoimmunity directed against the intracel …
They may be observed in autoimmune disorders triggered by an infectious agent, such as streptococcus in Sydenham's chorea …
Rheumatic Heart Disease: Pathogenesis and Vaccine.
Guilherme L, de Barros SF, Kohler KF, Santos SR, Ferreira FM, Silva WR, Alencar R, Postol E, Kalil J. Guilherme L, et al. Curr Protein Pept Sci. 2018;19(9):900-908. doi: 10.2174/1389203718666170725115855. Curr Protein Pept Sci. 2018. PMID: 28745221 Review.
Rheumatic fever (RF) and rheumatic heart disease (RHD) follow untreated S. pyogenes throat infections in children who present susceptible genes that favor the development of autoimmune reactions. ...Polyarthritis is the initial manifestation, which can evolve to carditis a …
Rheumatic fever (RF) and rheumatic heart disease (RHD) follow untreated S. pyogenes throat infections in children who present susceptible ge …
Movement disorders in autoimmune diseases.
Baizabal-Carvallo JF, Jankovic J. Baizabal-Carvallo JF, et al. Mov Disord. 2012 Jul;27(8):935-46. doi: 10.1002/mds.25011. Epub 2012 May 3. Mov Disord. 2012. PMID: 22555904 Review.
Movement disorders have been known to be associated with a variety of autoimmune diseases, including Sydenham's chorea, pediatric autoimmune neuropsychiatric disorders associated with streptococcus, systemic lupus erythematosus, antiphospholipid syndro …
Movement disorders have been known to be associated with a variety of autoimmune diseases, including Sydenham's chorea, pediat …
Molecular Mimicry, Autoimmunity, and Infection: The Cross-Reactive Antigens of Group A Streptococci and their Sequelae.
Cunningham MW. Cunningham MW. Microbiol Spectr. 2019 Jul;7(4):10.1128/microbiolspec.GPP3-0045-2018. doi: 10.1128/microbiolspec.GPP3-0045-2018. Microbiol Spectr. 2019. PMID: 31373269 Free PMC article. Review.
The pathogenesis of acute rheumatic fever, rheumatic heart disease, Sydenham chorea, and other autoimmune sequelae is related to autoantibodies that are characteristic of autoimmune diseases and result from the immune responses against group A streptococcal i …
The pathogenesis of acute rheumatic fever, rheumatic heart disease, Sydenham chorea, and other autoimmune sequelae is related …
Acute Rheumatic Fever and Rheumatic Heart Disease.
Sika-Paotonu D, Beaton A, Raghu A, Steer A, Carapetis J. Sika-Paotonu D, et al. 2017 Mar 10 [updated 2017 Apr 3]. In: Ferretti JJ, Stevens DL, Fischetti VA, editors. Streptococcus pyogenes: Basic Biology to Clinical Manifestations [Internet]. Oklahoma City (OK): University of Oklahoma Health Sciences Center; 2016–. Streptococcus pyogenes: Basic Biology to Clinical Manifestations. 2016–. PMID: 28379675 Free Books & Documents. Review.
Acute rheumatic fever (ARF) results from the body’s autoimmune response to a throat infection caused by Streptococcus pyogenes, also known as the group A Streptococcus bacteria. ...Symptoms of ARF can include polyarthritis, carditis, chorea, the appear …
Acute rheumatic fever (ARF) results from the body’s autoimmune response to a throat infection caused by Streptococcus pyogenes …
Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS).
Orefici G, Cardona F, Cox CJ, Cunningham MW. Orefici G, et al. 2016 Feb 10. In: Ferretti JJ, Stevens DL, Fischetti VA, editors. Streptococcus pyogenes: Basic Biology to Clinical Manifestations [Internet]. Oklahoma City (OK): University of Oklahoma Health Sciences Center; 2016–. Streptococcus pyogenes: Basic Biology to Clinical Manifestations. 2016–. PMID: 26866234 Free Books & Documents. Review.
The inclusion of a chapter on pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (or PANDAS) is essential to provide a history of the disease and provide current information about its association with Streptococcus pyogenes (gro …
The inclusion of a chapter on pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (or PANDAS) is …
Post-Streptococcal Autoimmune Sequelae: Rheumatic Fever and Beyond.
Cunningham MW. Cunningham MW. 2016 Feb 10. In: Ferretti JJ, Stevens DL, Fischetti VA, editors. Streptococcus pyogenes: Basic Biology to Clinical Manifestations [Internet]. Oklahoma City (OK): University of Oklahoma Health Sciences Center; 2016–. Streptococcus pyogenes: Basic Biology to Clinical Manifestations. 2016–. PMID: 26866235 Free Books & Documents. Review.
Molecular mimicry between the group A streptococcus, heart, and brain is supported by evidence from studies of human mAbs, human T cell clones, and serum IgG antibodies derived from streptococcal sequelae and rheumatic fever (Galvin, Hemric, Ward, & Cunningham, 2000; K …
Molecular mimicry between the group A streptococcus, heart, and brain is supported by evidence from studies of human mAbs, human T ce …
CNS autoimmune disease after Streptococcus pyogenes infections: animal models, cellular mechanisms and genetic factors.
Cutforth T, DeMille MM, Agalliu I, Agalliu D. Cutforth T, et al. Future Neurol. 2016 Dec;11(1):63-76. doi: 10.2217/fnl.16.4. Future Neurol. 2016. PMID: 27110222 Free PMC article.
Streptococcus pyogenes infections have been associated with two autoimmune diseases of the CNS: Sydenham's chorea (SC) and Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus infections (PANDAS). Despite the high freque …
Streptococcus pyogenes infections have been associated with two autoimmune diseases of the CNS: Sydenham's chorea (SC) …
Rheumatic fever, autoimmunity, and molecular mimicry: the streptococcal connection.
Cunningham MW. Cunningham MW. Int Rev Immunol. 2014 Jul-Aug;33(4):314-29. doi: 10.3109/08830185.2014.917411. Epub 2014 Jun 3. Int Rev Immunol. 2014. PMID: 24892819 Free PMC article. Review.
The group A streptococcus, Streptococcus pyogenes, and its link to autoimmune sequelae, has acquired a new level of understanding. ...In Sydenham chorea, human mAbs and their expression in transgenic mice have linked autoimmunity to central dopa …
The group A streptococcus, Streptococcus pyogenes, and its link to autoimmune sequelae, has acquired a new level of und …
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