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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1917 1
1922 1
1932 1
1935 1
1936 1
1937 1
1938 2
1939 1
1942 1
1944 2
1945 16
1946 9
1947 9
1948 13
1949 14
1950 9
1951 31
1952 42
1953 34
1954 27
1955 26
1956 42
1957 52
1958 50
1959 20
1960 17
1961 19
1962 12
1963 29
1964 62
1965 124
1966 129
1967 162
1968 164
1969 181
1970 178
1971 215
1972 221
1973 260
1974 334
1975 649
1976 691
1977 682
1978 723
1979 778
1980 854
1981 827
1982 850
1983 981
1984 1165
1985 1212
1986 1312
1987 1352
1988 1408
1989 1630
1990 1573
1991 1563
1992 1746
1993 1729
1994 1784
1995 1804
1996 1772
1997 1818
1998 1745
1999 1895
2000 2007
2001 2145
2002 2429
2003 2521
2004 2583
2005 2711
2006 3030
2007 3144
2008 3146
2009 3286
2010 3510
2011 4075
2012 4583
2013 4925
2014 5274
2015 5496
2016 5839
2017 6012
2018 6166
2019 6463
2020 6996
2021 6910
2022 6019
2023 5693
2024 7312
2025 4844

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138,998 results

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Page 1
Synthetic cathinones - From natural plant stimulant to new drug of abuse.
Pieprzyca E, Skowronek R, Nižnanský Ľ, Czekaj P. Pieprzyca E, et al. Eur J Pharmacol. 2020 May 15;875:173012. doi: 10.1016/j.ejphar.2020.173012. Epub 2020 Feb 19. Eur J Pharmacol. 2020. PMID: 32087255 Review.
As recreational substances, synthetic cathinones started to be used at the beginning of the 21st century. There is still limited data on these compounds, introduced to the illicit drug market for the most part after 2009. ...This review focuses on the availability o …
As recreational substances, synthetic cathinones started to be used at the beginning of the 21st century. There is still limited data …
Synthetic drug intoxication in children: recognition and management in the emergency department.
Shah R, Baum CR. Shah R, et al. Pediatr Emerg Med Pract. 2018 May;15(5):1-20. Epub 2018 May 1. Pediatr Emerg Med Pract. 2018. PMID: 29697923 Review.
When children and adolescents present to the emergency department with agitation or mental status changes, intoxication from synthetic drug use should be in the differential diagnosis. Identifying the responsible compound(s) may be difficult, so asking the patient b …
When children and adolescents present to the emergency department with agitation or mental status changes, intoxication from synthetic …
Smart Hydrogels - Synthetic Stimuli-Responsive Antitumor Drug Release Systems.
Kasiński A, Zielińska-Pisklak M, Oledzka E, Sobczak M. Kasiński A, et al. Int J Nanomedicine. 2020 Jun 25;15:4541-4572. doi: 10.2147/IJN.S248987. eCollection 2020. Int J Nanomedicine. 2020. PMID: 32617004 Free PMC article. Review.
Among modern drug formulations, stimuli-responsive hydrogels also called "smart hydrogels" deserve a special attention. ...External stimulus sensitivity allows remote control over the drug release profile and gel formation. On the other hand, internal factors provid …
Among modern drug formulations, stimuli-responsive hydrogels also called "smart hydrogels" deserve a special attention. ...External s …
Therapeutic applications of herbal/synthetic/bio-drug in oral cancer: An update.
Mosaddad SA, Beigi K, Doroodizadeh T, Haghnegahdar M, Golfeshan F, Ranjbar R, Tebyanian H. Mosaddad SA, et al. Eur J Pharmacol. 2021 Jan 5;890:173657. doi: 10.1016/j.ejphar.2020.173657. Epub 2020 Oct 21. Eur J Pharmacol. 2021. PMID: 33096111 Review.
Therefore, it is necessary to study and use drugs that are less risky for the patient as well as to provide solutions to reduce chemotherapy-induced adverse events that prevent many therapeutic risks. As mentioned above, this study examines low-risk therapies such as herba …
Therefore, it is necessary to study and use drugs that are less risky for the patient as well as to provide solutions to reduce chemo …
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update.
Smolen JS, Landewé RBM, Bijlsma JWJ, Burmester GR, Dougados M, Kerschbaumer A, McInnes IB, Sepriano A, van Vollenhoven RF, de Wit M, Aletaha D, Aringer M, Askling J, Balsa A, Boers M, den Broeder AA, Buch MH, Buttgereit F, Caporali R, Cardiel MH, De Cock D, Codreanu C, Cutolo M, Edwards CJ, van Eijk-Hustings Y, Emery P, Finckh A, Gossec L, Gottenberg JE, Hetland ML, Huizinga TWJ, Koloumas M, Li Z, Mariette X, Müller-Ladner U, Mysler EF, da Silva JAP, Poór G, Pope JE, Rubbert-Roth A, Ruyssen-Witrand A, Saag KG, Strangfeld A, Takeuchi T, Voshaar M, Westhovens R, van der Heijde D. Smolen JS, et al. Ann Rheum Dis. 2020 Jun;79(6):685-699. doi: 10.1136/annrheumdis-2019-216655. Epub 2020 Jan 22. Ann Rheum Dis. 2020. PMID: 31969328 Free article.
METHODS: An international task force considered new evidence supporting or contradicting previous recommendations and novel therapies and strategic insights based on two systematic literature searches on efficacy and safety of disease-modifying antirheumatic drugs (DMARDs) …
METHODS: An international task force considered new evidence supporting or contradicting previous recommendations and novel therapies and st …
Synthetic cannabinoids: epidemiology, pharmacodynamics, and clinical implications.
Castaneto MS, Gorelick DA, Desrosiers NA, Hartman RL, Pirard S, Huestis MA. Castaneto MS, et al. Drug Alcohol Depend. 2014 Nov 1;144:12-41. doi: 10.1016/j.drugalcdep.2014.08.005. Epub 2014 Aug 18. Drug Alcohol Depend. 2014. PMID: 25220897 Free PMC article. Review.
BACKGROUND: Synthetic cannabinoids (SC) are a heterogeneous group of compounds developed to probe the endogenous cannabinoid system or as potential therapeutics. Clandestine laboratories subsequently utilized published data to develop SC variations marketed as abusable des …
BACKGROUND: Synthetic cannabinoids (SC) are a heterogeneous group of compounds developed to probe the endogenous cannabinoid system o …
Artemisinin inspired synthetic endoperoxide drug candidates: Design, synthesis, and mechanism of action studies.
Woodley CM, Amado PSM, Cristiano MLS, O'Neill PM. Woodley CM, et al. Med Res Rev. 2021 Nov;41(6):3062-3095. doi: 10.1002/med.21849. Epub 2021 Aug 6. Med Res Rev. 2021. PMID: 34355414 Review.
Alarmingly, the rise of resistance to ART in South East Asia and the synthetic limitations of the ART scaffold have pushed the course for the necessity of fully synthetic endoperoxide-based antimalarials. Several classes of synthetic endoperoxide antimalarial …
Alarmingly, the rise of resistance to ART in South East Asia and the synthetic limitations of the ART scaffold have pushed the course …
Synthetic cathinones in drug-facilitated sexual assault: A case report involving the novel generation substituted cathinone N-ethylpentedrone and a review of the literature.
Drevin G, Gaulier JM, Hakim F, Gish A, Férec S, Renard L, Malbranque S, Briet M, Abbara C. Drevin G, et al. Forensic Sci Int. 2024 Jun;359:112030. doi: 10.1016/j.forsciint.2024.112030. Epub 2024 Apr 19. Forensic Sci Int. 2024. PMID: 38657324 Free article. Review.
The use of 3,4-methylenedioxymethamphetamine (MDMA) in drug-facilitated sexual assault (DFSA) is not uncommon. Indeed, the effects associated with the use of this substance may lead to disinhibition. Several synthetic cathinones, such as mephedrone or methylone, als …
The use of 3,4-methylenedioxymethamphetamine (MDMA) in drug-facilitated sexual assault (DFSA) is not uncommon. Indeed, the effects as …
Layered double hydroxides and their tailored hybrids/composites: Progressive trends for delivery of natural/synthetic-drug/cosmetic biomolecules.
Kumari S, Sharma V, Soni S, Sharma A, Thakur A, Kumar S, Dhama K, Sharma AK, Bhatia SK. Kumari S, et al. Environ Res. 2023 Dec 1;238(Pt 2):117171. doi: 10.1016/j.envres.2023.117171. Epub 2023 Sep 19. Environ Res. 2023. PMID: 37734578 Review.
Hence, HTs/LDHs and their modified and/or functionalized nanohybrids/nanocomposites are reported as the potential drug delivery carriers with a capability to stabilize the susceptible bioactive molecules, may enhance the solubility of poorly soluble drugs along with …
Hence, HTs/LDHs and their modified and/or functionalized nanohybrids/nanocomposites are reported as the potential drug delivery carri …
Bath salts and synthetic cathinones: an emerging designer drug phenomenon.
German CL, Fleckenstein AE, Hanson GR. German CL, et al. Life Sci. 2014 Feb 27;97(1):2-8. doi: 10.1016/j.lfs.2013.07.023. Epub 2013 Aug 2. Life Sci. 2014. PMID: 23911668 Free PMC article. Review.
Synthetic cathinones are an emerging class of designer drugs abused for psychostimulant and hallucinogenic effects similar to cocaine, methylenedioxymethamphetamine (MDMA), or other amphetamines. ...Recent pre-clinical and clinical studies indicate that dysregulatio …
Synthetic cathinones are an emerging class of designer drugs abused for psychostimulant and hallucinogenic effects similar to …
138,998 results
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