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Year Number of Results
2001 3
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2003 49
2004 94
2005 116
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2008 114
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2010 141
2011 125
2012 172
2013 187
2014 191
2015 184
2016 162
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3,084 results

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Tadalafil Alone or in Combination with Tamsulosin for the Management for LUTS/BPH and ED.
Sebastianelli A, Spatafora P, Morselli S, Vignozzi L, Serni S, McVary KT, Kaplan S, Gravas S, Chapple C, Gacci M. Sebastianelli A, et al. Curr Urol Rep. 2020 Oct 27;21(12):56. doi: 10.1007/s11934-020-01009-7. Curr Urol Rep. 2020. PMID: 33108544 Free PMC article. Review.
After discontinuation of tamsulosin or tadalafil in patients previously treated with their combination, the improvement of LUTS retains significance compared with baseline. Tadalafil 5 mg should be considered a primary treatment option for patients with LUTS/BPH and …
After discontinuation of tamsulosin or tadalafil in patients previously treated with their combination, the improvement of LUTS retai …
Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysis.
Gong B, Ma M, Xie W, Yang X, Huang Y, Sun T, Luo Y, Huang J. Gong B, et al. Int Urol Nephrol. 2017 Oct;49(10):1731-1740. doi: 10.1007/s11255-017-1644-5. Epub 2017 Jul 24. Int Urol Nephrol. 2017. PMID: 28741090 Free PMC article.
However, compared with sildenafil, tadalafil significantly improved psychological outcomes. Furthermore, the patients and their partners preferred tadalafil over sildenafil, and no significant difference was found in the adherence and persistence rates between ta
However, compared with sildenafil, tadalafil significantly improved psychological outcomes. Furthermore, the patients and their partn …
Tadalafil for the treatment of benign prostatic hyperplasia.
Mónica FZ, De Nucci G. Mónica FZ, et al. Expert Opin Pharmacother. 2019 Jun;20(8):929-937. doi: 10.1080/14656566.2019.1589452. Epub 2019 Mar 22. Expert Opin Pharmacother. 2019. PMID: 30901259 Review.
Areas covered: This article reviews the major preclinical and clinical data on PDE5 inhibitors with a specific focus on tadalafil. It includes details of the role of the nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) - PDE5 pathway in the LUT organs (bladder and p …
Areas covered: This article reviews the major preclinical and clinical data on PDE5 inhibitors with a specific focus on tadalafil. It …
Tamsulosin vs. Tadalafil as medical expulsive therapy for distal ureteral stones: a systematic review and meta-analysis.
Belkovsky M, Zogaib GV, Passerotti CC, Artifon ELA, Otoch JP, da Cruz JAS. Belkovsky M, et al. Int Braz J Urol. 2023 Nov-Dec;49(6):668-676. doi: 10.1590/S1677-5538.IBJU.2023.0345. Int Braz J Urol. 2023. PMID: 37903004 Free PMC article.
In this review, we aim to compare the effectiveness of tadalafil and tamsulosin for distal ureteral stones from 5 to 10 mm in terms of stone expulsion rate (SER), stone expulsion time (SET) and the side effect profile. ...RESULTS: Eleven publications with 1,330 patients we …
In this review, we aim to compare the effectiveness of tadalafil and tamsulosin for distal ureteral stones from 5 to 10 mm in terms o …
Efficacy and safety of long-term tadalafil 5 mg once daily combined with sildenafil 50 mg as needed at the early stage of treatment for patients with erectile dysfunction.
Cui H, Liu B, Song Z, Fang J, Deng Y, Zhang S, Wang H, Wang Z. Cui H, et al. Andrologia. 2015 Feb;47(1):20-4. doi: 10.1111/and.12216. Epub 2014 Jan 6. Andrologia. 2015. PMID: 24387078 Clinical Trial.
We enrolled 180 patients with ED 1 : 1 to tadalafil 5 mg once daily or once-a-day tadalafil 5 mg combined with sildenafil 50 mg as needed. ...Total IIEF-5 scores of patients with severe ED in combined medication group were significantly higher than in tadalafil
We enrolled 180 patients with ED 1 : 1 to tadalafil 5 mg once daily or once-a-day tadalafil 5 mg combined with sildenafil 50 m …
Tadalafil Facilitates the Distal Ureteral Stone Expulsion: A Meta-Analysis.
Bai Y, Yang Y, Wang X, Tang Y, Han P, Wang J. Bai Y, et al. J Endourol. 2017 Jun;31(6):557-563. doi: 10.1089/end.2016.0837. Epub 2017 Apr 6. J Endourol. 2017. PMID: 28384011 Review.
Randomized controlled trials evaluating effects of tadalafil for distal ureteral stones were included. RESULTS: Six publications involving 921 patients were included. ...CONCLUSIONS: Our study suggested that medical expulsive therapy for the distal ureteral stones using …
Randomized controlled trials evaluating effects of tadalafil for distal ureteral stones were included. RESULTS: Six publications invo …
Tadalafil and Steroid Hormones Interactions in Adipose, Bone and Prostate Tissues: Focus on Translational Perspectives.
Greco EA, Antinozzi C, Di Luigi L, Aversa A, Sgrò P. Greco EA, et al. Int J Mol Sci. 2022 Apr 11;23(8):4191. doi: 10.3390/ijms23084191. Int J Mol Sci. 2022. PMID: 35457011 Free PMC article. Review.
Tadalafil is a selective phosphodiesterase type-5 (PDE5) inhibitor that is approved for the treatment of men with erectile dysfunction (ED) and/or benign prostate hyperplasia (BPH) -associated symptoms. ...In this review, we summarize basic research and translational resul
Tadalafil is a selective phosphodiesterase type-5 (PDE5) inhibitor that is approved for the treatment of men with erectile dysfunctio
Benefits of Tadalafil and Sildenafil on Mortality, Cardiovascular Disease, and Dementia.
Jehle DVK, Sunesra R, Uddin H, Paul KK, Joglar AA, Michler OD, Blackwell TA, Gaalema D, Hayek S, Jneid H. Jehle DVK, et al. Am J Med. 2025 Mar;138(3):441-448.e3. doi: 10.1016/j.amjmed.2024.10.039. Epub 2024 Nov 10. Am J Med. 2025. PMID: 39532245
Men at least 40 years of age prescribed tadalafil or sildenafil after an erectile dysfunction diagnosis, or tadalafil after lower urinary tract symptom diagnoses, from 2004 to 2021 were included. ...CONCLUSIONS: In conclusion, tadalafil and sildenafil use in …
Men at least 40 years of age prescribed tadalafil or sildenafil after an erectile dysfunction diagnosis, or tadalafil after lo …
Tadalafil: in pulmonary arterial hypertension.
Croxtall JD, Lyseng-Williamson KA. Croxtall JD, et al. Drugs. 2010 Mar 5;70(4):479-88. doi: 10.2165/11204580-000000000-00000. Drugs. 2010. PMID: 20205489 Review.
Both the time to the first occurrence of clinical worsening and the incidence of clinical worsening were significantly reduced in recipients of tadalafil 40 mg once daily compared with recipients of placebo. Furthermore, at week 16, tadalafil improved most HR-QOL ou …
Both the time to the first occurrence of clinical worsening and the incidence of clinical worsening were significantly reduced in recipients …
Tadalafil Once a Day for Men with Erectile Dysfunction: Is It Superior than On-Demand Administration?
Prasetyo DT, Raharja PAR, Mantiri BJ, Ringoringo DRL, Rahman IA, Felizio J, Tambunan MP, Fadhly SF, Rahardjo HE. Prasetyo DT, et al. Acta Med Indones. 2019 Jul;51(3):275-281. Acta Med Indones. 2019. PMID: 31699953 Free article. Review.
BACKGROUND: Tadalafil is a PDE5I which has been licensed for the treatment of erectile dysfunction (ED) since 2003, is effective from 30 minutes after administration and its efficacy is maintained for up to 36 hours. ...CONCLUSION: administration of tadalafil OAD le …
BACKGROUND: Tadalafil is a PDE5I which has been licensed for the treatment of erectile dysfunction (ED) since 2003, is effective from …
3,084 results