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15 results
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DNA damage is able to induce senescence in tumor cells in vitro and in vivo.
te Poele RH, Okorokov AL, Jardine L, Cummings J, Joel SP. te Poele RH, et al. Cancer Res. 2002 Mar 15;62(6):1876-83. Cancer Res. 2002. PMID: 11912168 Free article.
RNA synthesis block by 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) triggers p53-dependent apoptosis in human colon carcinoma cells.
te Poele RH, Okorokov AL, Joel SP. te Poele RH, et al. Oncogene. 1999 Oct 14;18(42):5765-72. doi: 10.1038/sj.onc.1202961. Oncogene. 1999. PMID: 10523857
Schedule-dependent cytotoxicity of SN-38 in p53 wild-type and mutant colon adenocarcinoma cell lines.
te Poele RH, Joel SP. te Poele RH, et al. Br J Cancer. 1999 Dec;81(8):1285-93. doi: 10.1038/sj.bjc.6694370. Br J Cancer. 1999. PMID: 10604724 Free PMC article.
Gene expression profiling after radiation-induced DNA damage is strongly predictive of BRCA1 mutation carrier status.
Kote-Jarai Z, Williams RD, Cattini N, Copeland M, Giddings I, Wooster R, tePoele RH, Workman P, Gusterson B, Peacock J, Gui G, Campbell C, Eeles R. Kote-Jarai Z, et al. Clin Cancer Res. 2004 Feb 1;10(3):958-63. doi: 10.1158/1078-0432.ccr-1067-3. Clin Cancer Res. 2004. PMID: 14871973 Free article.
Cannabis-induced cytotoxicity in leukemic cell lines: the role of the cannabinoid receptors and the MAPK pathway.
Powles T, te Poele R, Shamash J, Chaplin T, Propper D, Joel S, Oliver T, Liu WM. Powles T, et al. Blood. 2005 Feb 1;105(3):1214-21. doi: 10.1182/blood-2004-03-1182. Epub 2004 Sep 28. Blood. 2005. PMID: 15454482
AHR- and DNA-damage-mediated gene expression responses induced by benzo(a)pyrene in human cell lines.
Hockley SL, Arlt VM, Brewer D, Te Poele R, Workman P, Giddings I, Phillips DH. Hockley SL, et al. Chem Res Toxicol. 2007 Dec;20(12):1797-810. doi: 10.1021/tx700252n. Epub 2007 Oct 19. Chem Res Toxicol. 2007. PMID: 17944540
AT13148 is a novel, oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity.
Yap TA, Walton MI, Grimshaw KM, Te Poele RH, Eve PD, Valenti MR, de Haven Brandon AK, Martins V, Zetterlund A, Heaton SP, Heinzmann K, Jones PS, Feltell RE, Reule M, Woodhead SJ, Davies TG, Lyons JF, Raynaud FI, Eccles SA, Workman P, Thompson NT, Garrett MD. Yap TA, et al. Among authors: te poele rh. Clin Cancer Res. 2012 Jul 15;18(14):3912-23. doi: 10.1158/1078-0432.CCR-11-3313. Epub 2012 Jul 10. Clin Cancer Res. 2012. PMID: 22781553 Free article.
Re: Loss of DNA mismatch repair: effects on the rate of mutation to drug resistance.
Liu WM, te Poele RH, Joel SP. Liu WM, et al. Among authors: te poele rh. J Natl Cancer Inst. 1998 Feb 4;90(3):246-7. doi: 10.1093/jnci/90.3.246. J Natl Cancer Inst. 1998. PMID: 9462684 No abstract available.
Disruption of WT1 gene expression and exon 5 splicing following cytotoxic drug treatment: antisense down-regulation of exon 5 alters target gene expression and inhibits cell survival.
Renshaw J, Orr RM, Walton MI, Te Poele R, Williams RD, Wancewicz EV, Monia BP, Workman P, Pritchard-Jones K. Renshaw J, et al. Mol Cancer Ther. 2004 Nov;3(11):1467-84. Mol Cancer Ther. 2004. PMID: 15542786
Role of E2F3 expression in modulating cellular proliferation rate in human bladder and prostate cancer cells.
Olsson AY, Feber A, Edwards S, Te Poele R, Giddings I, Merson S, Cooper CS. Olsson AY, et al. Oncogene. 2007 Feb 15;26(7):1028-37. doi: 10.1038/sj.onc.1209854. Epub 2006 Aug 14. Oncogene. 2007. PMID: 16909110
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