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A pgk::hprt fusion as a selectable marker for targeting of genes in mouse embryonic stem cells: disruption of the T-cell receptor delta-chain-encoding gene.
van der Lugt N, Maandag ER, te Riele H, Laird PW, Berns A. van der Lugt N, et al. Gene. 1991 Sep 15;105(2):263-7. doi: 10.1016/0378-1119(91)90161-4. Gene. 1991. PMID: 1834524
Adenosine-deaminase-deficient mice die perinatally and exhibit liver-cell degeneration, atelectasis and small intestinal cell death.
Migchielsen AA, Breuer ML, van Roon MA, te Riele H, Zurcher C, Ossendorp F, Toutain S, Hershfield MS, Berns A, Valerio D. Migchielsen AA, et al. Nat Genet. 1995 Jul;10(3):279-87. doi: 10.1038/ng0795-279. Nat Genet. 1995. PMID: 7670465
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs.
Schinkel AH, Smit JJ, van Tellingen O, Beijnen JH, Wagenaar E, van Deemter L, Mol CA, van der Valk MA, Robanus-Maandag EC, te Riele HP, et al. Schinkel AH, et al. Cell. 1994 May 20;77(4):491-502. doi: 10.1016/0092-8674(94)90212-7. Cell. 1994. PMID: 7910522
Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene.
van der Lugt NM, Domen J, Linders K, van Roon M, Robanus-Maandag E, te Riele H, van der Valk M, Deschamps J, Sofroniew M, van Lohuizen M, et al. van der Lugt NM, et al. Genes Dev. 1994 Apr 1;8(7):757-69. doi: 10.1101/gad.8.7.757. Genes Dev. 1994. PMID: 7926765
Mouse models for hereditary nonpolyposis colorectal cancer.
de Wind N, Dekker M, van Rossum A, van der Valk M, te Riele H. de Wind N, et al. Cancer Res. 1998 Jan 15;58(2):248-55. Cancer Res. 1998. PMID: 9443401
p107 is a suppressor of retinoblastoma development in pRb-deficient mice.
Robanus-Maandag E, Dekker M, van der Valk M, Carrozza ML, Jeanny JC, Dannenberg JH, Berns A, te Riele H. Robanus-Maandag E, et al. Genes Dev. 1998 Jun 1;12(11):1599-609. doi: 10.1101/gad.12.11.1599. Genes Dev. 1998. PMID: 9620848 Free PMC article.
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