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Year Number of Results
2001 3
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Page 1
Tenofovir Alafenamide.
Gibson AK, Shah BM, Nambiar PH, Schafer JJ. Gibson AK, et al. Ann Pharmacother. 2016 Nov;50(11):942-952. doi: 10.1177/1060028016660812. Epub 2016 Jul 28. Ann Pharmacother. 2016. PMID: 27465879 Review.
OBJECTIVE: To review the pharmacology, efficacy, safety, and place in therapy for tenofovir alafenamide (TAF). DATA SOURCES: A search using PubMed was conducted (2004 to May 2016) using the following keywords: tenofovir alafenamide, TAF, and GS-7340. . …
OBJECTIVE: To review the pharmacology, efficacy, safety, and place in therapy for tenofovir alafenamide (TAF). DATA SOURCES: A …
Tenofovir alafenamide fumarate.
Lee WA, Cheng AK. Lee WA, et al. Antivir Ther. 2022 Apr;27(2):13596535211067600. doi: 10.1177/13596535211067600. Antivir Ther. 2022. PMID: 35499175 Free article.
Tenofovir alafenamide fumarate is a lipophilic prodrug of tenofovir which is preferentially metabolized in lymphatic tissue resulting in high concentrations of tenofovir (TFV) and its active diphosphate metabolite inside the cells that replicate HIV. Due to its sele …
Tenofovir alafenamide fumarate is a lipophilic prodrug of tenofovir which is preferentially metabolized in lymphatic tissue re …
Tenofovir alafenamide revisited.
Di Perri G. Di Perri G. Infez Med. 2020 Dec 1;28(4):525-533. Infez Med. 2020. PMID: 33257626 Free article.
Two Tenofovir pro-drugs are available for the treatment of HIV and HBV infection. Tenofovir Alafenamide (TAF) was clinically developed as a safer alternative to the older Tenofovir Disoproxil Fumarate (TDF) as the latter was consistently found to be associated to pr …
Two Tenofovir pro-drugs are available for the treatment of HIV and HBV infection. Tenofovir Alafenamide (TAF) was clinically d …
Eight-year efficacy and safety of tenofovir alafenamide for treatment of chronic hepatitis B virus infection: Final results from two randomised phase 3 trials.
Buti M, Lim YS, Chan HLY, Agarwal K, Marcellin P, Brunetto MR, Chuang WL, Janssen HLA, Fung SK, Izumi N, Jablkowski MS, Abdurakhmanov D, Abramov F, Wang H, Botros I, Yee LJ, Mateo R, Flaherty JF, Osinusi A, Pan CQ, Shalimar X, Seto WK, Gane EJ. Buti M, et al. Aliment Pharmacol Ther. 2024 Dec;60(11-12):1573-1586. doi: 10.1111/apt.18278. Epub 2024 Sep 27. Aliment Pharmacol Ther. 2024. PMID: 39327857 Free PMC article. Clinical Trial.
BACKGROUND: In two phase 3 studies, tenofovir alafenamide (TAF) showed non-inferior efficacy versus tenofovir disoproxil fumarate (TDF), with more favourable renal and bone safety in patients with chronic hepatitis B (CHB). ...
BACKGROUND: In two phase 3 studies, tenofovir alafenamide (TAF) showed non-inferior efficacy versus tenofovir disoproxil fumar …
Tenofovir Alafenamide: A Review in Chronic Hepatitis B.
Scott LJ, Chan HLY. Scott LJ, et al. Drugs. 2017 Jun;77(9):1017-1028. doi: 10.1007/s40265-017-0754-9. Drugs. 2017. PMID: 28493172 Review.
Tenofovir alafenamide (AF) [Vemlidy( )], an oral prodrug of tenofovir, was developed to optimize the antiviral potency and clinical safety of the active moiety tenofovir diphosphate (selective reverse transcriptase nucleotide inhibitor). ...
Tenofovir alafenamide (AF) [Vemlidy( )], an oral prodrug of tenofovir, was developed to optimize the antiviral potency and cli …
Tenofovir alafenamide nephrotoxicity: a case report and literature review.
Ueaphongsukkit T, Gatechompol S, Avihingsanon A, Surintrspanont J, Iampenkhae K, Avihingsanon Y, Udomkarnjananun S. Ueaphongsukkit T, et al. AIDS Res Ther. 2021 Aug 21;18(1):53. doi: 10.1186/s12981-021-00380-w. AIDS Res Ther. 2021. PMID: 34419091 Free PMC article. Review.
BACKGROUND: Tenofovir alafenamide (TAF), a novel prodrug of tenofovir (TFV), has become the preferred drug for the treatment of HIV-1 and chronic hepatitis B infection in clinical practice. ...
BACKGROUND: Tenofovir alafenamide (TAF), a novel prodrug of tenofovir (TFV), has become the preferred drug for the treatment o …
Tenofovir alafenamide (TAF) treatment of HBV, what are the unanswered questions?
Viganò M, Loglio A, Grossi G, Lampertico P. Viganò M, et al. Expert Rev Anti Infect Ther. 2018 Feb;16(2):153-161. doi: 10.1080/14787210.2018.1428561. Epub 2018 Jan 23. Expert Rev Anti Infect Ther. 2018. PMID: 29338458 Review.
However, reduced kidney function and loss of bone mineral density have been reported in some CHB patients treated with TDF. Consequent to these safety issues, tenofovir alafenamide (TAF) [Vemlidy ], a phosphonate prodrug of TFV, was developed for the treatment of CH …
However, reduced kidney function and loss of bone mineral density have been reported in some CHB patients treated with TDF. Consequent to th …
Tenofovir Alafenamide for the Treatment of Chronic Hepatitis B Monoinfection.
Childs-Kean LM, Egelund EF, Jourjy J. Childs-Kean LM, et al. Pharmacotherapy. 2018 Oct;38(10):1051-1057. doi: 10.1002/phar.2174. Epub 2018 Sep 9. Pharmacotherapy. 2018. PMID: 30120841 Review.
Tenofovir alafenamide (TAF) is indicated for adult patients with chronic hepatitis B virus (HBV) infection with compensated liver disease at an oral dose of 25 mg/day. ...
Tenofovir alafenamide (TAF) is indicated for adult patients with chronic hepatitis B virus (HBV) infection with compensated li …
Tenofovir alafenamide use in pregnant and lactating women living with HIV.
Eke AC, Brooks KM, Gebreyohannes RD, Sheffield JS, Dooley KE, Mirochnick M. Eke AC, et al. Expert Opin Drug Metab Toxicol. 2020 Apr;16(4):333-342. doi: 10.1080/17425255.2020.1738384. Epub 2020 Mar 17. Expert Opin Drug Metab Toxicol. 2020. PMID: 32125906 Free PMC article. Review.
Introduction: Tenofovir alafenamide (TAF)-containing fixed-dose drug combinations (FDCs) are increasingly being used in managing pregnant women living with HIV. ...
Introduction: Tenofovir alafenamide (TAF)-containing fixed-dose drug combinations (FDCs) are increasingly being used in managi …
1,952 results