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1989 4
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241 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Terbinafine in the treatment of dermatophyte toenail onychomycosis: a meta-analysis of efficacy for continuous and intermittent regimens.
Gupta AK, Paquet M, Simpson F, Tavakkol A. Gupta AK, et al. J Eur Acad Dermatol Venereol. 2013 Mar;27(3):267-72. doi: 10.1111/j.1468-3083.2012.04584.x. Epub 2012 May 28. J Eur Acad Dermatol Venereol. 2013. PMID: 22632057 Review.
The pulse regimen that demonstrated consistently comparable results to the continuous terbinafine regimen was two pulses of terbinafine 250 mg/day for 4 weeks on/4 weeks off. ...In contrast, some pulse terbinafine regimens were as effective as continuous t
The pulse regimen that demonstrated consistently comparable results to the continuous terbinafine regimen was two pulses of terbin
Terbinafine in fungal infections of the nails: a meta-analysis of randomized clinical trials.
Haugh M, Helou S, Boissel JP, Cribier BJ. Haugh M, et al. Br J Dermatol. 2002 Jul;147(1):118-21. doi: 10.1046/j.1365-2133.2002.04825.x. Br J Dermatol. 2002. PMID: 12100193 Review.
RESULTS: Three trials were included in which terbinafine was compared with placebo. From four trials comparing terbinafine with itraconazole, a statistically significant advantage in favour of terbinafine was observed for negative culture and microscopy at th …
RESULTS: Three trials were included in which terbinafine was compared with placebo. From four trials comparing terbinafine wit …
Systematic review of severe acute liver injury caused by terbinafine.
Yan J, Wang X, Chen S. Yan J, et al. Int J Clin Pharm. 2014 Aug;36(4):679-83. doi: 10.1007/s11096-014-9969-y. Epub 2014 Jul 2. Int J Clin Pharm. 2014. PMID: 24986266 Review.
BACKGROUND: Terbinafine is an effective antimicrobial agent against dermatophytes, cryptococcus and other fungi. ...However, severe acute hepatitis from oral terbinafine administration has been recently reported. AIM: To describe a representative case, and review th …
BACKGROUND: Terbinafine is an effective antimicrobial agent against dermatophytes, cryptococcus and other fungi. ...However, severe a …
Terbinafine Hydrochloride Combined With Itraconazole for Fungal Skin Diseases: A Randomized Controlled Trial.
Zhang D, Liao W, Chen C, Lai H, Liu S. Zhang D, et al. Am J Ther. 2021 Mar-Apr 01;28(2):e179-e186. doi: 10.1097/MJT.0000000000001075. Am J Ther. 2021. PMID: 33687025 Clinical Trial.
BACKGROUND: Terbinafine and itraconazole are the common antifungal drugs in clinic. In vitro experiments proved that terbinafine combined with itraconazole achieves better antifungal effects. ...CONCLUSIONS: Compared with terbinafine or itraconazole monothera …
BACKGROUND: Terbinafine and itraconazole are the common antifungal drugs in clinic. In vitro experiments proved that terbinafine
Meta-analysis of randomized, controlled trials comparing particular doses of griseofulvin and terbinafine for the treatment of tinea capitis.
Gupta AK, Drummond-Main C. Gupta AK, et al. Pediatr Dermatol. 2013 Jan-Feb;30(1):1-6. doi: 10.1111/j.1525-1470.2012.01866.x. Epub 2012 Sep 20. Pediatr Dermatol. 2013. PMID: 22994156 Review.
Two oral antifungal agents, griseofulvin and terbinafine, have regulatory approval in the United States, but it is unknown whether one has superior overall efficacy. ...For tinea capitis caused by Microsporum spp., griseofulvin is superior (p = 0.04), whereas terbinafin
Two oral antifungal agents, griseofulvin and terbinafine, have regulatory approval in the United States, but it is unknown whether on …
Effect of terbinafine and voriconazole on the pharmacokinetics of the antidepressant venlafaxine.
Hynninen VV, Olkkola KT, Bertilsson L, Kurkinen K, Neuvonen PJ, Laine K. Hynninen VV, et al. Clin Pharmacol Ther. 2008 Feb;83(2):342-8. doi: 10.1038/sj.clpt.6100311. Epub 2007 Aug 8. Clin Pharmacol Ther. 2008. PMID: 17687273 Clinical Trial.
This study investigated the effect of terbinafine and voriconazole on the pharmacokinetics of venlafaxine in healthy volunteers. ...Terbinafine decreased the AUC(0-infinity) ratio of ODV over venlafaxine by 82% (P<0.001). ...
This study investigated the effect of terbinafine and voriconazole on the pharmacokinetics of venlafaxine in healthy volunteers. ... …
Effects of terbinafine and itraconazole on the pharmacokinetics of orally administered tramadol.
Saarikoski T, Saari TI, Hagelberg NM, Backman JT, Neuvonen PJ, Scheinin M, Olkkola KT, Laine K. Saarikoski T, et al. Eur J Clin Pharmacol. 2015 Mar;71(3):321-7. doi: 10.1007/s00228-014-1799-2. Epub 2015 Jan 6. Eur J Clin Pharmacol. 2015. PMID: 25560051 Clinical Trial.
Terbinafine reduced subjective drug effect of tramadol (P < 0.001). Itraconazole had minor effects on tramadol pharmacokinetics. CONCLUSIONS: Terbinafine may reduce the opioid effect of tramadol and increase the risk of its monoaminergic adverse effects. ...
Terbinafine reduced subjective drug effect of tramadol (P < 0.001). Itraconazole had minor effects on tramadol pharmacokinetics. C
Mupirocin vs terbinafine in impetigo.
Ciftci E, Guriz H, Aysev AD. Ciftci E, et al. Indian J Pediatr. 2002 Aug;69(8):679-82. doi: 10.1007/BF02722704. Indian J Pediatr. 2002. PMID: 12356219 Clinical Trial.

Twenty-five and 23 patients were treated with mupirocin and terbinafine, respectively. The clinical cure rates were 100% for the mupirocin group and 70% for the terbinafine group (p < 0.05). The bacteriological eradication rate for mupirocin-treated children was

Twenty-five and 23 patients were treated with mupirocin and terbinafine, respectively. The clinical cure rates were 100% for the mupi …
Efficacy of oral terbinafine versus itraconazole in treatment of dermatophytic infection of skin - A prospective, randomized comparative study.
Bhatia A, Kanish B, Badyal DK, Kate P, Choudhary S. Bhatia A, et al. Indian J Pharmacol. 2019 Mar-Apr;51(2):116-119. doi: 10.4103/ijp.IJP_578_17. Indian J Pharmacol. 2019. PMID: 31142947 Free PMC article. Clinical Trial.
OBJECTIVES: Dermatophytic infections are the common fungal infections aggravated by hot and humid climate. Terbinafine and itraconazole are commonly used oral antifungal agents for the same. However, resistance to these drugs is being seen increasingly when used in the con …
OBJECTIVES: Dermatophytic infections are the common fungal infections aggravated by hot and humid climate. Terbinafine and itraconazo …
Oral terbinafine in toenail dermatophytosis. A double-blind, placebo-controlled multicenter study with 12 months' follow-up.
Svejgaard EL, Brandrup F, Kragballe K, Larsen PO, Veien NK, Holst M, Andersen BL, Bro-Jørgensen AV, Dahl JC, Frentz G, Graudal C, Kamp P, Kroman N, Larsen FS, Mikkelsen F, Munkvad JM, Olafsson JH, Rothenborg H, Staberg B, Søndergaard J, Thulin H. Svejgaard EL, et al. Acta Derm Venereol. 1997 Jan;77(1):66-9. doi: 10.2340/0001555555776669. Acta Derm Venereol. 1997. PMID: 9059684 Free article. Clinical Trial.
The treatment of onychomycosis has previously often been protracted and unsuccessful. Terbinafine has been shown to be effective in short-term regimens. In this double-blind, placebo-controlled study, 148 patients with toenail dermatophytosis were randomized to treatment w …
The treatment of onychomycosis has previously often been protracted and unsuccessful. Terbinafine has been shown to be effective in s …
241 results