The Endocannabinoid System and its Modulation by Phytocannabinoids.
Neurotherapeutics. 2015.
PMID: 26271952
Free PMC article.
Review.
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The Endocannabinoid System and its Modulation by Phytocannabinoids.
Neurotherapeutics. 2015 Oct;12(4):692-8. doi: 10.1007/s13311-015-0374-6.
Neurotherapeutics. 2015.
PMID: 26271952
Free PMC article.
Review.
The endocannabinoid system is currently defined as the ensemble of the two 7-transmembrane-domain and G protein-coupled receptors for delta(9)-tetrahydrocannabinol (but not for most other plant cannabinoids or phytocannabinoids)-cannabinoid receptor type-1 (C …
The endocannabinoid system is currently defined as the ensemble of the two 7-transmembrane-domain and G protein-coupled recept …
The Endocannabinoid System: A Potential Target for the Treatment of Various Diseases.
Int J Mol Sci. 2021 Aug 31;22(17):9472. doi: 10.3390/ijms22179472.
Int J Mol Sci. 2021.
PMID: 34502379
Free PMC article.
Review.
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a balance in internal environment (temperature, mood, and immune system) and energy input and output in living, biological systems. ...This modulation results …
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a balance in internal environment (temp …
The Endocannabinoid System and its Modulation by Cannabidiol (CBD).
Altern Ther Health Med. 2019 Jun;25(S2):6-14.
Altern Ther Health Med. 2019.
PMID: 31202198
The endocannabinoid system (ECS) is an extensive endogenous signaling system with multiple elements, the number of which may be increasing as scientists continue to elucidate its role in human health and disease. The ECS is seemingly ubiquitous in animal spec …
The endocannabinoid system (ECS) is an extensive endogenous signaling system with multiple elements, the number of whic …
Cannabis, the Endocannabinoid System and Immunity-the Journey from the Bedside to the Bench and Back.
Int J Mol Sci. 2020 Jun 23;21(12):4448. doi: 10.3390/ijms21124448.
Int J Mol Sci. 2020.
PMID: 32585801
Free PMC article.
Review.
The phyto-cannabinoid activity is mediated by the endocannabinoid system. Cannabinoids affect the nervous system and play significant roles in the regulation of the immune system. ...In this contemporary review, we discuss the roles of the endocanna …
The phyto-cannabinoid activity is mediated by the endocannabinoid system. Cannabinoids affect the nervous system and pl …
A narrative review of molecular mechanism and therapeutic effect of cannabidiol (CBD).
Basic Clin Pharmacol Toxicol. 2022 Apr;130(4):439-456. doi: 10.1111/bcpt.13710. Epub 2022 Feb 6.
Basic Clin Pharmacol Toxicol. 2022.
PMID: 35083862
Free article.
Review.
Cannabidiol (CBD) is an abundant non-psychoactive phytocannabinoid in cannabis extracts which has high affinity on a series of receptors, including Type 1 cannabinoid receptor (CB1), Type 2 cannabinoid receptor (CB2), GPR55, transient receptor potential vanilloid (TRPV) an …
Cannabidiol (CBD) is an abundant non-psychoactive phytocannabinoid in cannabis extracts which has high affinity on a series of recept …
Molecular Mechanism and Cannabinoid Pharmacology.
Handb Exp Pharmacol. 2020;258:323-353. doi: 10.1007/164_2019_298.
Handb Exp Pharmacol. 2020.
PMID: 32236882
Free PMC article.
CB(1) receptors mediate the cannabimimetic effects of THC and are highly expressed on presynaptic neurons in the nervous system, where they modulate neurotransmitter release. In contrast, CB(2) receptors are primarily expressed on immune cells. The endocannabinoi …
CB(1) receptors mediate the cannabimimetic effects of THC and are highly expressed on presynaptic neurons in the nervous system, wher …
Phytocannabinoids, the Endocannabinoid System and Male Reproduction.
World J Mens Health. 2023 Jan;41(1):1-10. doi: 10.5534/wjmh.220132.
World J Mens Health. 2023.
PMID: 36578200
Free PMC article.
Review.
The endocannabinoid system (ECS) is comprised of a set of lipid-derived messengers (the endocannabinoids, ECBs), proteins that control their production and degradation, and cell-surface cannabinoid (CB) receptors that transduce their actions. ...It is neverth …
The endocannabinoid system (ECS) is comprised of a set of lipid-derived messengers (the endocannabinoids, ECBs), protei …
Cannabis and its constituents for cancer: History, biogenesis, chemistry and pharmacological activities.
Pharmacol Res. 2021 Jan;163:105302. doi: 10.1016/j.phrs.2020.105302. Epub 2020 Nov 24.
Pharmacol Res. 2021.
PMID: 33246167
Review.
Over 400 bioactive constituents, including more than 100 phytocannabinoids, have been isolated from this plant. The non-psychoactive cannabidiol (CBD) and the psychoactive delta(9)-tetrahydrocannabinol (delta(9)-THC) are the major and widely studied constituents from this …
Over 400 bioactive constituents, including more than 100 phytocannabinoids, have been isolated from this plant. The non-psychoactive …
The role of cannabinoids in pain modulation in companion animals.
Front Vet Sci. 2023 Jan 4;9:1050884. doi: 10.3389/fvets.2022.1050884. eCollection 2022.
Front Vet Sci. 2023.
PMID: 36686189
Free PMC article.
Review.
This review aims to examine the role of cannabinoids in pain modulation by analyzing scientific findings regarding the signaling pathways of the endocannabinoid system and discussing the analgesic effects of synthetic cannabinoids compared to cannabinoid extr …
This review aims to examine the role of cannabinoids in pain modulation by analyzing scientific findings regarding the signaling path …
Exploring the versatile roles of the endocannabinoid system and phytocannabinoids in modulating bacterial infections.
Infect Immun. 2024 Jun 11;92(6):e0002024. doi: 10.1128/iai.00020-24. Epub 2024 May 22.
Infect Immun. 2024.
PMID: 38775488
Free PMC article.
Review.
The endocannabinoid system (ECS), initially identified for its role in maintaining homeostasis, particularly in regulating brain function, has evolved into a complex orchestrator influencing various physiological processes beyond its original association with the ne …
The endocannabinoid system (ECS), initially identified for its role in maintaining homeostasis, particularly in regulating bra …
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