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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 1
1985 1
1986 1
1987 5
1988 3
1989 8
1990 8
1991 7
1992 7
1993 9
1994 12
1995 11
1996 17
1997 13
1998 21
1999 14
2000 19
2001 18
2002 16
2003 17
2004 30
2005 36
2006 30
2007 36
2008 31
2009 28
2010 27
2011 30
2012 32
2013 34
2014 31
2015 26
2016 36
2017 34
2018 37
2019 27
2020 39
2021 36
2022 53
2023 45
2024 24

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812 results

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3 articles found by citation matching

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Page 1
Metformin in aging and aging-related diseases: clinical applications and relevant mechanisms.
Chen S, Gan D, Lin S, Zhong Y, Chen M, Zou X, Shao Z, Xiao G. Chen S, et al. Theranostics. 2022 Mar 6;12(6):2722-2740. doi: 10.7150/thno.71360. eCollection 2022. Theranostics. 2022. PMID: 35401820 Free PMC article. Review.
Aging is a natural process, which plays a critical role in the pathogenesis of a variety of diseases, i.e., aging-related diseases, such as diabetes, osteoarthritis, Alzheimer disease, cardiovascular diseases, cancers, obesity and other metabolic abnormalitie …
Aging is a natural process, which plays a critical role in the pathogenesis of a variety of diseases, i.e., aging-related diseases, s …
Mendelian Randomisation Confirms the Role of Y-Chromosome Loss in Alzheimer's Disease Aetiopathogenesis in Men.
García-González P, de Rojas I, Moreno-Grau S, Montrreal L, Puerta R, Alarcón-Martín E, Quintela I, Orellana A, Andrade V, Adami PVM, Heilmann-Heimbach S, Gomez-Garre P, Periñán MT, Alvarez I, Diez-Fairen M, Nuñez Llaves R, Olivé Roig C, Garcia-Ribas G, Menéndez-González M, Martínez C, Aguilar M, Buongiorno M, Franco-Macías E, Saez ME, Cano A, Bullido MJ, Real LM, Rodríguez-Rodríguez E, Royo JL, Álvarez V, Pastor P, Piñol-Ripoll G, Mir P, Lara MC, Padilla MM, Sánchez-Juan P, Carracedo A, Valero S, Hernandez I, Tàrraga L, Ramirez A, Boada M, Ruiz A. García-González P, et al. Int J Mol Sci. 2023 Jan 4;24(2):898. doi: 10.3390/ijms24020898. Int J Mol Sci. 2023. PMID: 36674414 Free PMC article.
Mosaic loss of chromosome Y (mLOY) is a common ageing-related somatic event and has been previously associated with Alzheimer's disease (AD). ...Importantly, mloy-PRS had no effect on AD conversion or risk in the female group, suggesting that these ass …
Mosaic loss of chromosome Y (mLOY) is a common ageing-related somatic event and has been previously associated with Alzheimer' …
The Role of TREML2 in Alzheimer's Disease.
Wang SY, Gong PY, E Y, Zhang YD, Jiang T. Wang SY, et al. J Alzheimers Dis. 2020;76(3):799-806. doi: 10.3233/JAD-200406. J Alzheimers Dis. 2020. PMID: 32568208 Review.
Late-onset Alzheimer's disease (AD) accounts for most of all AD casesand is currently considered a complex disorder caused by a combination of environmental and genetic factors. ...Emerging evidence implied a potential role of TREML2 in the susceptibil …
Late-onset Alzheimer's disease (AD) accounts for most of all AD casesand is currently considered a complex disorder cau …
USP25 inhibition ameliorates Alzheimer's pathology through the regulation of APP processing and Abeta generation.
Zheng Q, Song B, Li G, Cai F, Wu M, Zhao Y, Jiang L, Guo T, Shen M, Hou H, Zhou Y, Zhao Y, Di A, Zhang L, Zeng F, Zhang XF, Luo H, Zhang X, Zhang H, Zeng Z, Huang TY, Dong C, Qing H, Zhang Y, Zhang Q, Wang X, Wu Y, Xu H, Song W, Wang X. Zheng Q, et al. J Clin Invest. 2022 Mar 1;132(5):e152170. doi: 10.1172/JCI152170. J Clin Invest. 2022. PMID: 35229730 Free PMC article.
Down syndrome (DS), or trisomy 21, is one of the critical risk factors for early-onset Alzheimer's disease (AD), implicating key roles for chromosome 21-encoded genes in the pathogenesis of AD. We previously identified a role for the deubiquitin …
Down syndrome (DS), or trisomy 21, is one of the critical risk factors for early-onset Alzheimer's disease (AD), implic …
Genetically predicted telomere length and Alzheimer's disease endophenotypes: a Mendelian randomization study.
Rodríguez-Fernández B, Vilor-Tejedor N, Arenaza-Urquijo EM, Sánchez-Benavides G, Suárez-Calvet M, Operto G, Minguillón C, Fauria K, Kollmorgen G, Suridjan I, de Moura MC, Piñeyro D, Esteller M, Blennow K, Zetterberg H, De Vivo I, Molinuevo JL, Navarro A, Gispert JD, Sala-Vila A, Crous-Bou M; ALFA study. Rodríguez-Fernández B, et al. Alzheimers Res Ther. 2022 Nov 7;14(1):167. doi: 10.1186/s13195-022-01101-9. Alzheimers Res Ther. 2022. PMID: 36345036 Free PMC article.
Telomere length (TL) is associated with biological aging, consequently influencing the risk of age-related diseases such as Alzheimer's disease (AD). We aimed to evaluate the potential causal role of TL in AD endophenotypes (i.e., cognitive performance …
Telomere length (TL) is associated with biological aging, consequently influencing the risk of age-related diseases such as Alzheimer
The Role of Glia Telomere Dysfunction in the Pathogenesis of Central Nervous System Diseases.
Papageorgakopoulou MA, Bania A, Lagogianni IA, Birmpas K, Assimakopoulou M. Papageorgakopoulou MA, et al. Mol Neurobiol. 2024 Aug;61(8):5868-5881. doi: 10.1007/s12035-024-03947-6. Epub 2024 Jan 19. Mol Neurobiol. 2024. PMID: 38240992 Free PMC article. Review.
Telomere shortening of microglial cells has been widely associated with the onset and progression of neurodegenerative diseases such as Parkinson's and Alzheimer's disease. Additionally, traumatic brain injury appears to have a positive correlation with the t …
Telomere shortening of microglial cells has been widely associated with the onset and progression of neurodegenerative diseases such as Park …
The Emerging Role of Long Noncoding RNAs in Human Disease.
DiStefano JK. DiStefano JK. Methods Mol Biol. 2018;1706:91-110. doi: 10.1007/978-1-4939-7471-9_6. Methods Mol Biol. 2018. PMID: 29423795 Review.
An increasing number of experimental studies are providing evidence that lncRNAs mediate disease pathogenesis, thereby challenging the concept that protein-coding genes are the sole contributors to the development of human disease. This chapter highlights recent fin …
An increasing number of experimental studies are providing evidence that lncRNAs mediate disease pathogenesis, thereby challenging th …
The X Files: "The Mystery of X Chromosome Instability in Alzheimer's Disease".
Bajic VP, Essack M, Zivkovic L, Stewart A, Zafirovic S, Bajic VB, Gojobori T, Isenovic E, Spremo-Potparevic B. Bajic VP, et al. Front Genet. 2020 Jan 28;10:1368. doi: 10.3389/fgene.2019.01368. eCollection 2019. Front Genet. 2020. PMID: 32047510 Free PMC article. Review.
Alzheimer's disease (AD) is a neurodegenerative disease that affects millions of individuals worldwide and can occur relatively early or later in life. ...In this review, we examine the role of X chromosome epigenetics and, based upon GWA
Alzheimer's disease (AD) is a neurodegenerative disease that affects millions of individuals worldwide and can o
A New Discovery of MicroRNA-455-3p in Alzheimer's Disease.
Kumar S, Reddy PH. Kumar S, et al. J Alzheimers Dis. 2019;72(s1):S117-S130. doi: 10.3233/JAD-190583. J Alzheimers Dis. 2019. PMID: 31524168 Review.
Recently, our laboratory discovered the biomarker and therapeutic relevance of miR-455-3p in Alzheimer's disease (AD). Our global microarray analysis of serum samples from AD patients, mild cognitive individuals (MCI), and healthy subjects unveiled the high l …
Recently, our laboratory discovered the biomarker and therapeutic relevance of miR-455-3p in Alzheimer's disease (AD). …
Exploring the potential role of rab5 protein in endo-lysosomal impairment in Alzheimer's disease.
Behl T, Kaur D, Sehgal A, Singh S, Makeen HA, Albratty M, Abdellatif AAH, Dachani SR, Bungau S. Behl T, et al. Biomed Pharmacother. 2022 Apr;148:112773. doi: 10.1016/j.biopha.2022.112773. Epub 2022 Mar 1. Biomed Pharmacother. 2022. PMID: 35245734 Free article. Review.
The discovery of several chromosomal factors for Alzheimer's disease that are clinically linked to regulation of the endocytic pathway, including protein aggregation and removal, supports the theory that the endo-lysosomal/autophagic torrent is more su …
The discovery of several chromosomal factors for Alzheimer's disease that are clinically linked to regulation of …
812 results