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3,492 results

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Filters applied: Review. Clear all
Page 1
The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies.
Wiertsema SP, van Bergenhenegouwen J, Garssen J, Knippels LMJ. Wiertsema SP, et al. Nutrients. 2021 Mar 9;13(3):886. doi: 10.3390/nu13030886. Nutrients. 2021. PMID: 33803407 Free PMC article. Review.
With 70-80% of immune cells being present in the gut, there is an intricate interplay between the intestinal microbiota, the intestinal epithelial layer, and the local mucosal immune system. ...Clinicians are more and more using the increased knowledge …
With 70-80% of immune cells being present in the gut, there is an intricate interplay between the intestinal microbiota, the i …
Role of the microbiota in immunity and inflammation.
Belkaid Y, Hand TW. Belkaid Y, et al. Cell. 2014 Mar 27;157(1):121-41. doi: 10.1016/j.cell.2014.03.011. Cell. 2014. PMID: 24679531 Free PMC article. Review.
The microbiota plays a fundamental role on the induction, training, and function of the host immune system. ...When operating optimally, this immune system-microbiota alliance allows the induction of protective responses to pathoge …
The microbiota plays a fundamental role on the induction, training, and function of the host immune system. ...W …
Nutritional Components in Western Diet Versus Mediterranean Diet at the Gut Microbiota-Immune System Interplay. Implications for Health and Disease.
García-Montero C, Fraile-Martínez O, Gómez-Lahoz AM, Pekarek L, Castellanos AJ, Noguerales-Fraguas F, Coca S, Guijarro LG, García-Honduvilla N, Asúnsolo A, Sanchez-Trujillo L, Lahera G, Bujan J, Monserrat J, Álvarez-Mon M, Álvarez-Mon MA, Ortega MA. García-Montero C, et al. Nutrients. 2021 Feb 22;13(2):699. doi: 10.3390/nu13020699. Nutrients. 2021. PMID: 33671569 Free PMC article. Review.
In this context, diet is the greatest modulator of immune system-microbiota crosstalk, and much interest, and new challenges, are arising in the area of precision nutrition as a way towards treatment and prevention. ...Thus, the purpose of this review is to d …
In this context, diet is the greatest modulator of immune system-microbiota crosstalk, and much interest, and new chall …
Role of the microbiome in human development.
Dominguez-Bello MG, Godoy-Vitorino F, Knight R, Blaser MJ. Dominguez-Bello MG, et al. Gut. 2019 Jun;68(6):1108-1114. doi: 10.1136/gutjnl-2018-317503. Epub 2019 Jan 22. Gut. 2019. PMID: 30670574 Free PMC article. Review.
This coevolution has likely shaped evolving phenotypes in all life forms on this predominantly microbial planet. The microbiota seems to exert effects on the next generation from gestation, via maternal microbiota and immune responses. The microbiota e …
This coevolution has likely shaped evolving phenotypes in all life forms on this predominantly microbial planet. The microbiota seems …
The Dynamics of the Skin's Immune System.
Nguyen AV, Soulika AM. Nguyen AV, et al. Int J Mol Sci. 2019 Apr 12;20(8):1811. doi: 10.3390/ijms20081811. Int J Mol Sci. 2019. PMID: 31013709 Free PMC article. Review.
Deregulation of immune responses often leads to impaired healing and poor tissue restoration and function. In this review, we will discuss the defensive components of the skin and focus on the function of skin-resident immune cells in homeostasis and their role …
Deregulation of immune responses often leads to impaired healing and poor tissue restoration and function. In this review, we will di …
How colonization by microbiota in early life shapes the immune system.
Gensollen T, Iyer SS, Kasper DL, Blumberg RS. Gensollen T, et al. Science. 2016 Apr 29;352(6285):539-44. doi: 10.1126/science.aad9378. Science. 2016. PMID: 27126036 Free PMC article. Review.
Microbial colonization of mucosal tissues during infancy plays an instrumental role in the development and education of the host mammalian immune system. These early-life events can have long-standing consequences: facilitating tolerance to environmental expo …
Microbial colonization of mucosal tissues during infancy plays an instrumental role in the development and education of the host mamm …
Gut microbiota in the pathogenesis of inflammatory bowel disease.
Nishida A, Inoue R, Inatomi O, Bamba S, Naito Y, Andoh A. Nishida A, et al. Clin J Gastroenterol. 2018 Feb;11(1):1-10. doi: 10.1007/s12328-017-0813-5. Epub 2017 Dec 29. Clin J Gastroenterol. 2018. PMID: 29285689 Review.
The most accepted hypothesis of IBD pathogenesis is that complex interactions between genetics, environmental factors, and the host immune system lead to aberrant immune responses and chronic intestinal inflammation. The human gut harbors a complex and abunda …
The most accepted hypothesis of IBD pathogenesis is that complex interactions between genetics, environmental factors, and the host immun …
The role of T cells in age-related diseases.
Carrasco E, Gómez de Las Heras MM, Gabandé-Rodríguez E, Desdín-Micó G, Aranda JF, Mittelbrunn M. Carrasco E, et al. Nat Rev Immunol. 2022 Feb;22(2):97-111. doi: 10.1038/s41577-021-00557-4. Epub 2021 Jun 7. Nat Rev Immunol. 2022. PMID: 34099898 Review.
Age-related T cell dysfunction can lead to failure of immune tolerance mechanisms, resulting in aberrant T cell-driven cytokine and cytotoxic responses that ultimately cause tissue damage. ...We present different mechanisms by which T cells contribute to inflammageing and …
Age-related T cell dysfunction can lead to failure of immune tolerance mechanisms, resulting in aberrant T cell-driven cytokine and c …
The First Microbial Colonizers of the Human Gut: Composition, Activities, and Health Implications of the Infant Gut Microbiota.
Milani C, Duranti S, Bottacini F, Casey E, Turroni F, Mahony J, Belzer C, Delgado Palacio S, Arboleya Montes S, Mancabelli L, Lugli GA, Rodriguez JM, Bode L, de Vos W, Gueimonde M, Margolles A, van Sinderen D, Ventura M. Milani C, et al. Microbiol Mol Biol Rev. 2017 Nov 8;81(4):e00036-17. doi: 10.1128/MMBR.00036-17. Print 2017 Dec. Microbiol Mol Biol Rev. 2017. PMID: 29118049 Free PMC article. Review.
The human gut microbiota is engaged in multiple interactions affecting host health during the host's entire life span. ...Finally, we discuss the relevance of key microbial players of the infant gut microbiota, in particular bifidobacteria, with respect to their …
The human gut microbiota is engaged in multiple interactions affecting host health during the host's entire life span. ...Finally, we …
The role of the gut microbiota in multiple sclerosis.
Correale J, Hohlfeld R, Baranzini SE. Correale J, et al. Nat Rev Neurol. 2022 Sep;18(9):544-558. doi: 10.1038/s41582-022-00697-8. Epub 2022 Aug 5. Nat Rev Neurol. 2022. PMID: 35931825 Review.
In this Review, we examine the influence that the gut microbiota have on immune function via modulation of serotonin production in the gut and through complex interactions with components of the immune system, such as T cells and B cells. We then prese …
In this Review, we examine the influence that the gut microbiota have on immune function via modulation of serotonin productio …
3,492 results