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154,913 results

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Page 1
The threonine story.
Debabov VG. Debabov VG. Adv Biochem Eng Biotechnol. 2003;79:113-36. doi: 10.1007/3-540-45989-8_4. Adv Biochem Eng Biotechnol. 2003. PMID: 12523390 Review.
L-Threonine is an essential amino acid which has recently been brought into agricultural industry for balancing the livestock feed. L-Threonine is produced by microbial synthesis using glucose or sucrose as substrates. For the process to be cost-effective, the micro …
L-Threonine is an essential amino acid which has recently been brought into agricultural industry for balancing the livestock feed. L …
Why Threonine Is an Essential Amino Acid in Mammals and Birds: Studies at the Enzyme Level.
Malinovsky AV. Malinovsky AV. Biochemistry (Mosc). 2018 Jul;83(7):795-799. doi: 10.1134/S0006297918070039. Biochemistry (Mosc). 2018. PMID: 30200864 Review.
However, using radiolabeled isotopes, synthesis of threonine was demonstrated in rat liver and in a reaction mixture containing chicken liver threonine dehydrogenase. In the review, we discuss why threonine is an essential amino acid in mammals and birds base …
However, using radiolabeled isotopes, synthesis of threonine was demonstrated in rat liver and in a reaction mixture containing chick …
Microbial Production of l-Threonine Using Metabolically Engineered Escherichia coli.
Nie Y, Tian Y, Ren X, Liang J, Li B, Xiong ZQ. Nie Y, et al. J Agric Food Chem. 2025 Jun 4;73(22):13125-13141. doi: 10.1021/acs.jafc.5c01453. Epub 2025 May 23. J Agric Food Chem. 2025. PMID: 40407267 Review.
Multiple metabolic engineering approaches have been implemented to develop efficient l-threonine microbial cell factories, providing theoretical insights to support industrial-scale l-threonine production. ...Lastly, the challenges in constructing efficient l-thr …
Multiple metabolic engineering approaches have been implemented to develop efficient l-threonine microbial cell factories, providing …
Reason for Indispensability of Threonine in Humans and Other Mammals in Comparative Aspect.
Malinovsky AV. Malinovsky AV. Biochemistry (Mosc). 2017 Sep;82(9):1055-1060. doi: 10.1134/S0006297917090097. Biochemistry (Mosc). 2017. PMID: 28988535 Review.
Because the decomposition of threonine catalyzed by threonine dehydratase is irreversible, in the present work attention is focused on threonine dehydrogenase to show the inability of this enzyme to synthesize threonine in a reaction that would be the …
Because the decomposition of threonine catalyzed by threonine dehydratase is irreversible, in the present work attention is fo …
Serine/Threonine Ligation and Cysteine/Penicillamine Ligation.
Liu J, Li X. Liu J, et al. Methods Mol Biol. 2022;2530:33-43. doi: 10.1007/978-1-0716-2489-0_3. Methods Mol Biol. 2022. PMID: 35761040
Serine/threonine ligation (STL) and cysteine/penicillamine ligation (CPL) are highly chemo- and regioselective reactions between unprotected peptides with C-terminus salicylaldehyde esters and unprotected peptides with N-terminus serine/threonine or cysteine/penicil …
Serine/threonine ligation (STL) and cysteine/penicillamine ligation (CPL) are highly chemo- and regioselective reactions between unpr …
Threonine Cavities Are Targetable Motifs That Control Alpha-Synuclein Fibril Growth.
Nathan Kochen N, Vasandani V, Seaney D, Pandey AK, Walters MA, Braun AR, Sachs JN. Nathan Kochen N, et al. ACS Chem Neurosci. 2022 Sep 7;13(17):2646-2657. doi: 10.1021/acschemneuro.2c00327. Epub 2022 Aug 24. ACS Chem Neurosci. 2022. PMID: 36001084 Free PMC article.
Harnessing the first such structures, we previously used molecular dynamics and free energy calculations to suggest that threonines 72 and 75 which line water-filled cavities within the fibril stacks may be of central importance in stabilizing fibrils. Here, we used experi …
Harnessing the first such structures, we previously used molecular dynamics and free energy calculations to suggest that threonines 7 …
Threonine and valine influx into brain.
[No authors listed] [No authors listed] Nutr Rev. 1987 Oct;45(10):315-7. doi: 10.1111/j.1753-4887.1987.tb06340.x. Nutr Rev. 1987. PMID: 3122128 Review. No abstract available.
Dietary threonine prevented stress-related mucosal diseases in rats.
An JM, Kang EA, Han YM, Kim YS, Hong YG, Hah BS, Hong SP, Hahm KB. An JM, et al. J Physiol Pharmacol. 2019 Jun;70(3). doi: 10.26402/jpp.2019.3.14. Epub 2019 Sep 27. J Physiol Pharmacol. 2019. PMID: 31566193 Free article.
The water immersion-restraint stress (WIRS) was used in rats and additional groups were pretreated with threonine alone or the combination of threonine and lignin. Based on gross and microscopic evaluations, threonine alone or the combination of threonine …
The water immersion-restraint stress (WIRS) was used in rats and additional groups were pretreated with threonine alone or the combin …
Specific roles of threonine in intestinal mucosal integrity and barrier function.
Mao X, Zeng X, Qiao S, Wu G, Li D. Mao X, et al. Front Biosci (Elite Ed). 2011 Jun 1;3(4):1192-200. doi: 10.2741/e322. Front Biosci (Elite Ed). 2011. PMID: 21622125 Free article. Review.
A large proportion of dietary threonine is utilized for intestinal-mucosal protein synthesis, especially for mucin synthesis, and there is no oxidation of threonine by enterocytes. Because mucin proteins cannot be digested and reused, intestinal mucin secretion is a …
A large proportion of dietary threonine is utilized for intestinal-mucosal protein synthesis, especially for mucin synthesis, and the …
Threonine production by microorganisms: a review.
Bhattacharyya R, Das Y, Samanta TK, Mondal S, Chatterjee SP. Bhattacharyya R, et al. Hindustan Antibiot Bull. 1988 Aug-Nov;30(3-4):54-65. Hindustan Antibiot Bull. 1988. PMID: 3151369 Review. No abstract available.
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