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50-year trends in smoking-related mortality in the United States.
Thun MJ, Carter BD, Feskanich D, Freedman ND, Prentice R, Lopez AD, Hartge P, Gapstur SM. Thun MJ, et al. N Engl J Med. 2013 Jan 24;368(4):351-64. doi: 10.1056/NEJMsa1211127. N Engl J Med. 2013. PMID: 23343064 Free PMC article.
Whether these risks have continued to increase during the past 20 years is unclear. METHODS: We measured temporal trends in mortality across three time periods (1959-1965, 1982-1988, and 2000-2010), comparing absolute and relative risks according to sex and self-reported s …
Whether these risks have continued to increase during the past 20 years is unclear. METHODS: We measured temporal trends in mortality …
Common genetic variants in prostate cancer risk prediction--results from the NCI Breast and Prostate Cancer Cohort Consortium (BPC3).
Lindström S, Schumacher FR, Cox D, Travis RC, Albanes D, Allen NE, Andriole G, Berndt SI, Boeing H, Bueno-de-Mesquita HB, Crawford ED, Diver WR, Gaziano JM, Giles GG, Giovannucci E, Gonzalez CA, Henderson B, Hunter DJ, Johansson M, Kolonel LN, Ma J, Le Marchand L, Pala V, Stampfer M, Stram DO, Thun MJ, Tjonneland A, Trichopoulos D, Virtamo J, Weinstein SJ, Willett WC, Yeager M, Hayes RB, Severi G, Haiman CA, Chanock SJ, Kraft P. Lindström S, et al. Cancer Epidemiol Biomarkers Prev. 2012 Mar;21(3):437-44. doi: 10.1158/1055-9965.EPI-11-1038. Epub 2012 Jan 11. Cancer Epidemiol Biomarkers Prev. 2012. PMID: 22237985 Free PMC article.
RESULTS: The best risk model (C-statistic = 0.642) included individual genetic markers and family history of prostate cancer. We observed a decreasing trend in discriminative ability with advancing age (P = 0.009), with highest accuracy in men younger than 60 years (C-stat …
RESULTS: The best risk model (C-statistic = 0.642) included individual genetic markers and family history of prostate cancer. We observed a …