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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 4
1982 4
1983 9
1984 8
1985 8
1986 4
1987 10
1988 5
1989 12
1990 20
1991 20
1992 26
1993 18
1994 19
1995 13
1996 20
1997 11
1998 5
1999 11
2000 14
2001 15
2002 15
2003 25
2004 27
2005 18
2006 23
2007 58
2008 18
2009 26
2010 50
2011 45
2012 71
2013 57
2014 37
2015 48
2016 45
2017 38
2018 47
2019 31
2020 15
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877 results
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Page 1
Thymosin beta 4 regulation of actin in sepsis.
Belsky JB, Rivers EP, Filbin MR, Lee PJ, Morris DC. Belsky JB, et al. Expert Opin Biol Ther. 2018 Jul;18(sup1):193-197. doi: 10.1080/14712598.2018.1448381. Epub 2018 Mar 6. Expert Opin Biol Ther. 2018. PMID: 29508629 Free PMC article. Review.
AREAS COVERED: The authors summarize the current knowledge of actin and Thymosin Beta 4 as it relates to sepsis via a comprehensive literature search. ...Given that Thymosin Beta 4 inhibits the polymerization of F-actin, it is possible th …
AREAS COVERED: The authors summarize the current knowledge of actin and Thymosin Beta 4 as it relates to sepsis via a c …
Thymosin beta 4 and the eye: the journey from bench to bedside.
Sosne G. Sosne G. Expert Opin Biol Ther. 2018 Jul;18(sup1):99-104. doi: 10.1080/14712598.2018.1486818. Expert Opin Biol Ther. 2018. PMID: 30063853 Review.
Thymosin beta 4 (Tbeta4) has important applications in ocular repair and Phase 3 clinical trials using Tbeta4 to treat dry eye and neurotrophic keratopathy are currently ongoing. ...
Thymosin beta 4 (Tbeta4) has important applications in ocular repair and Phase 3 clinical trials using Tbeta4 to treat
Cardioprotection by Thymosin Beta 4.
Pipes GT, Yang J. Pipes GT, et al. Vitam Horm. 2016;102:209-26. doi: 10.1016/bs.vh.2016.04.004. Epub 2016 May 31. Vitam Horm. 2016. PMID: 27450736 Review.
Treatment with thymosin beta 4 (Tbeta4) reduces infarct volume and preserves cardiac function in preclinical models of cardiac ischemic injury. ...
Treatment with thymosin beta 4 (Tbeta4) reduces infarct volume and preserves cardiac function in preclinical models of …
Thymosin beta 4 attenuates PrP(106-126)-induced human brain endothelial cells dysfunction.
Song K, Han HJ, Kim S, Kwon J. Song K, et al. Eur J Pharmacol. 2020 Feb 15;869:172891. doi: 10.1016/j.ejphar.2019.172891. Epub 2019 Dec 23. Eur J Pharmacol. 2020. PMID: 31877278
Prion diseases are neurodegenerative pathologies characterized by the accumulation of altered forms of the prion protein (PrP), named PrP(Sc). Thymosin beta 4 (Tbeta(4)) is an actin-sequestering peptide known to bind monomeric actin and inhibit its pol …
Prion diseases are neurodegenerative pathologies characterized by the accumulation of altered forms of the prion protein (PrP), named PrP(Sc …
Thymosin Beta 4: A Potential Novel Therapy for Neurotrophic Keratopathy, Dry Eye, and Ocular Surface Diseases.
Sosne G, Rimmer D, Kleinman HK, Ousler G. Sosne G, et al. Vitam Horm. 2016;102:277-306. doi: 10.1016/bs.vh.2016.04.012. Epub 2016 Jul 5. Vitam Horm. 2016. PMID: 27450739 Review.
A focus on treatments that reduce the inflammatory responses while accelerating corneal epithelial growth would represent a major step forward from current treatment options. Increasing evidence suggests that thymosin beta 4 (Tbeta4), a naturally occurring po …
A focus on treatments that reduce the inflammatory responses while accelerating corneal epithelial growth would represent a major step forwa …
Thymosin beta 4 interactions.
Bubb MR. Bubb MR. Vitam Horm. 2003;66:297-316. doi: 10.1016/s0083-6729(03)01008-2. Vitam Horm. 2003. PMID: 12852258 Review.
Thymosin beta 4 is largely unfolded or perhaps completely unfolded in solution. ...Furthermore, if multiple ligands bind to thymosin beta 4, then it is possible that thymosin beta 4 has a unique integrative function t
Thymosin beta 4 is largely unfolded or perhaps completely unfolded in solution. ...Furthermore, if multiple ligands bin
Thymosin Beta 4 Is a Potential Regulator of Hepatic Stellate Cells.
Kim J, Jung Y. Kim J, et al. Vitam Horm. 2016;102:121-49. doi: 10.1016/bs.vh.2016.04.011. Epub 2016 May 31. Vitam Horm. 2016. PMID: 27450733 Review.
During liver injury, hepatic stellate cells (HSCs) undergo transdifferentiation from quiescent HSCs into activated HSCs, which promote the deposition of extracellular matrix proteins, leading to liver fibrosis. Thymosin beta 4 (Tbeta4), a major actin-sequeste …
During liver injury, hepatic stellate cells (HSCs) undergo transdifferentiation from quiescent HSCs into activated HSCs, which promote the d …
Thymosin beta 4-Induced Autophagy Increases Cholinergic Signaling in PrP (106-126)-Treated HT22 Cells.
Han HJ, Kim S, Kwon J. Han HJ, et al. Neurotox Res. 2019 Jul;36(1):58-65. doi: 10.1007/s12640-018-9985-0. Epub 2018 Dec 15. Neurotox Res. 2019. PMID: 30552633
Autophagy has been shown to provide protective functions for neurodegenerative diseases, including prion disease. Thymosin beta 4 (Tbeta(4)) plays a key role in the nervous system, providing a neuronal growth effect that includes motility, neurite outg …
Autophagy has been shown to provide protective functions for neurodegenerative diseases, including prion disease. Thymosin beta
Loss of endogenous thymosin beta(4) accelerates glomerular disease.
Vasilopoulou E, Kolatsi-Joannou M, Lindenmeyer MT, White KE, Robson MG, Cohen CD, Sebire NJ, Riley PR, Winyard PJ, Long DA. Vasilopoulou E, et al. Kidney Int. 2016 Nov;90(5):1056-1070. doi: 10.1016/j.kint.2016.06.032. Epub 2016 Aug 26. Kidney Int. 2016. PMID: 27575556 Free PMC article.
However, the role of endogenous thymosin beta(4) in the kidney is unknown. We demonstrate that thymosin beta(4) is expressed prominently in podocytes of developing and adult mouse glomeruli. ...Lack of thymosin beta(4
However, the role of endogenous thymosin beta(4) in the kidney is unknown. We demonstrate that thymosin beta
Ethosomal Gel for Improving Transdermal Delivery of Thymosin beta-4.
Fu X, Shi Y, Wang H, Zhao X, Sun Q, Huang Y, Qi T, Lin G. Fu X, et al. Int J Nanomedicine. 2019 Nov 27;14:9275-9284. doi: 10.2147/IJN.S228863. eCollection 2019. Int J Nanomedicine. 2019. PMID: 31819429 Free PMC article.
PURPOSE: Thymosin beta-4(Tbeta-4) is a macromolecular protein drug with potential for drug development in wound repair but is limited by the shortcomings of macromolecular protein, such as large volumes, poor membrane permeability, and unstable physico …
PURPOSE: Thymosin beta-4(Tbeta-4) is a macromolecular protein drug with potential for drug development in wound …
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