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Year Number of Results
2000 1
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47 results

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Page 1
beta-Thymosins.
Hannappel E. Hannappel E. Ann N Y Acad Sci. 2007 Sep;1112:21-37. doi: 10.1196/annals.1415.018. Epub 2007 Apr 27. Ann N Y Acad Sci. 2007. PMID: 17468232 Review.
The development of thymosin beta(4) from a thymic hormone to an actin-sequestering peptide and back to a cytokine supporting wound healing will be outlined. ...Several biological effects are attributed to thymosin beta(4), o …
The development of thymosin beta(4) from a thymic hormone to an actin-sequestering peptide and back to a cytokine suppo …
Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance.
Mendias CL, Awan TM. Mendias CL, et al. Sports Med. 2026 Aug;56(8):1921-1935. doi: 10.1007/s40279-026-02437-0. Epub 2026 Apr 12. Sports Med. 2026. PMID: 41966639 Review.
Our objective is to present the pharmacological mechanisms, safety profiles, and regulatory status of prominent approved and unapproved peptides marketed direct to patients, including AOD-9604 (anti-obesity drug 9604), BPC-157 (body protection compound 157), CJC-1295, FS-344 (fol …
Our objective is to present the pharmacological mechanisms, safety profiles, and regulatory status of prominent approved and unapproved pept …
Thymosin beta 4 and the eye: the journey from bench to bedside.
Sosne G. Sosne G. Expert Opin Biol Ther. 2018 Jul;18(sup1):99-104. doi: 10.1080/14712598.2018.1486818. Expert Opin Biol Ther. 2018. PMID: 30063853 Review.
Thymosin beta 4 (Tbeta4) has important applications in ocular repair and Phase 3 clinical trials using Tbeta4 to treat dry eye and neurotrophic keratopathy are currently ongoing. ...As a tribute to the amazing individuals who have guided and supported …
Thymosin beta 4 (Tbeta4) has important applications in ocular repair and Phase 3 clinical trials using Tbeta4 to …
Thymosin beta-4 denotes new directions towards developing prosperous anti-aging regenerative therapies.
Bock-Marquette I, Maar K, Maar S, Lippai B, Faskerti G, Gallyas F Jr, Olson EN, Srivastava D. Bock-Marquette I, et al. Int Immunopharmacol. 2023 Mar;116:109741. doi: 10.1016/j.intimp.2023.109741. Epub 2023 Jan 27. Int Immunopharmacol. 2023. PMID: 36709593 Free article. Review.
Since initial approaches utilizing only progenitor cells appear limited, we propose interconnecting our collective knowledge regarding aging and embryonic development may lead to the discovery of molecules which provide alternatives to effectively reverse cellular damage. In this …
Since initial approaches utilizing only progenitor cells appear limited, we propose interconnecting our collective knowledge regarding aging …
Thymosin beta4: A Multi-Faceted Tissue Repair Stimulating Protein in Heart Injury.
Bjørklund G, Dadar M, Aaseth J, Chirumbolo S. Bjørklund G, et al. Curr Med Chem. 2020;27(37):6294-6305. doi: 10.2174/0929867326666190716125456. Curr Med Chem. 2020. PMID: 31333080 Review.
Thymosin Beta-4 (Tbeta4) is known as a major pleiotropic actin-sequestering protein that is involved in tumorigenesis. ...Furthermore, Tbeta4 may act in skeletal muscle and different organs in association/synergism with numerous other tissue repair …
Thymosin Beta-4 (Tbeta4) is known as a major pleiotropic actin-sequestering protein that is involved in tumorigenesis. …
Thymosin Beta 4 Is a Potential Regulator of Hepatic Stellate Cells.
Kim J, Jung Y. Kim J, et al. Vitam Horm. 2016;102:121-49. doi: 10.1016/bs.vh.2016.04.011. Epub 2016 May 31. Vitam Horm. 2016. PMID: 27450733 Review.
Thymosin beta 4 (Tbeta4), a major actin-sequestering protein, is the most abundant member of the highly conserved beta-thymosin family and controls cell morphogenesis and motility by regulating the dynamics of the actin cytoskeleton. Tbeta4 is known to …
Thymosin beta 4 (Tbeta4), a major actin-sequestering protein, is the most abundant member of the highly conserved beta- …
Animal studies with thymosin beta, a multifunctional tissue repair and regeneration peptide.
Philp D, Kleinman HK. Philp D, et al. Ann N Y Acad Sci. 2010 Apr;1194:81-6. doi: 10.1111/j.1749-6632.2010.05479.x. Ann N Y Acad Sci. 2010. PMID: 20536453 Review.
Studies in various animal models of disease and repair with thymosin beta(4) (Tbeta(4)), the major actin-sequestering molecule in mammalian cells, have provided the scientific foundation for the ongoing dermal, corneal, and cardiac wound repa …
Studies in various animal models of disease and repair with thymosin beta(4) (Tbeta(4)), the major actin-sequest …
Thymosin beta4 Promotes Dermal Healing.
Kleinman HK, Sosne G. Kleinman HK, et al. Vitam Horm. 2016;102:251-75. doi: 10.1016/bs.vh.2016.04.005. Epub 2016 May 24. Vitam Horm. 2016. PMID: 27450738 Review.
No agent has been identified that significantly accelerates the repair of chronic dermal wounds in humans. Thymosin beta 4 (Tbeta4) is a small, abundant, naturally occurring regenerative protein that is found in body fluids and inside cells. ...It is s …
No agent has been identified that significantly accelerates the repair of chronic dermal wounds in humans. Thymosin beta …
Thymosin Beta 4: A Potential Novel Therapy for Neurotrophic Keratopathy, Dry Eye, and Ocular Surface Diseases.
Sosne G, Rimmer D, Kleinman HK, Ousler G. Sosne G, et al. Vitam Horm. 2016;102:277-306. doi: 10.1016/bs.vh.2016.04.012. Epub 2016 Jul 5. Vitam Horm. 2016. PMID: 27450739 Review.
Treatment choices depend on the type and severity of the disease, but in general positive outcomes are limited because many of these treatments do not fully address the underlying disease process or promote mechanisms that facilitate long-term wound repair. From min …
Treatment choices depend on the type and severity of the disease, but in general positive outcomes are limited because many of these treatme …
Thymosin beta4 limits inflammation through autophagy.
Renga G, Oikonomou V, Stincardini C, Pariano M, Borghi M, Costantini C, Bartoli A, Garaci E, Goldstein AL, Romani L. Renga G, et al. Expert Opin Biol Ther. 2018 Jul;18(sup1):171-175. doi: 10.1080/14712598.2018.1473854. Expert Opin Biol Ther. 2018. PMID: 30063848 Review.
INTRODUCTION: Thymosin beta4 (Tbeta4) is a thymic hormone with multiple and different intracellular and extracellular activities affecting wound healing, inflammation, fibrosis and tissue regeneration. ...EXPERT OPINION: Based on its multitasking activ …
INTRODUCTION: Thymosin beta4 (Tbeta4) is a thymic hormone with multiple and different intracellular and extracellular activities affe …
47 results