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Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan.
Longo VD, Panda S. Longo VD, et al. Cell Metab. 2016 Jun 14;23(6):1048-1059. doi: 10.1016/j.cmet.2016.06.001. Cell Metab. 2016. PMID: 27304506 Free PMC article. Review.
Both intermittent and periodic fasting result in benefits ranging from the prevention to the enhanced treatment of diseases. Similarly, time-restricted feeding (TRF), in which food consumption is restricted to certain hours of the day, al …
Both intermittent and periodic fasting result in benefits ranging from the prevention to the enhanced treatment of diseases. S …
Time-Restricted Eating, Intermittent Fasting, and Fasting-Mimicking Diets in Weight Loss.
Fanti M, Mishra A, Longo VD, Brandhorst S. Fanti M, et al. Curr Obes Rep. 2021 Jun;10(2):70-80. doi: 10.1007/s13679-021-00424-2. Epub 2021 Jan 29. Curr Obes Rep. 2021. PMID: 33512641 Review.
PURPOSE OF REVIEW: This article reviews the current literature on dietary interventions, including time-restricted eating (TRE), intermittent fasting (IF), and fasting-mimicking diets (FMD) and their effects on weight loss. ...Here we present an …
PURPOSE OF REVIEW: This article reviews the current literature on dietary interventions, including time-restricted eating (TRE …
Impact of intermittent fasting on health and disease processes.
Mattson MP, Longo VD, Harvie M. Mattson MP, et al. Ageing Res Rev. 2017 Oct;39:46-58. doi: 10.1016/j.arr.2016.10.005. Epub 2016 Oct 31. Ageing Res Rev. 2017. PMID: 27810402 Free PMC article. Review.
Because animals, including humans, evolved in environments where food was relatively scarce, they developed numerous adaptations that enabled them to function at a high level, both physically and cognitively, when in a food-deprived/fasted state. Intermittent fasting …
Because animals, including humans, evolved in environments where food was relatively scarce, they developed numerous adaptations that enable …
International consensus on fasting terminology.
Koppold DA, Breinlinger C, Hanslian E, Kessler C, Cramer H, Khokhar AR, Peterson CM, Tinsley G, Vernieri C, Bloomer RJ, Boschmann M, Bragazzi NL, Brandhorst S, Gabel K, Goldhamer AC, Grajower MM, Harvie M, Heilbronn L, Horne BD, Karras SN, Langhorst J, Lischka E, Madeo F, Mitchell SJ, Papagiannopoulos-Vatopaidinos IE, Papagiannopoulou M, Pijl H, Ravussin E, Ritzmann-Widderich M, Varady K, Adamidou L, Chihaoui M, de Cabo R, Hassanein M, Lessan N, Longo V, Manoogian ENC, Mattson MP, Muhlestein JB, Panda S, Papadopoulou SK, Rodopaios NE, Stange R, Michalsen A. Koppold DA, et al. Cell Metab. 2024 Aug 6;36(8):1779-1794.e4. doi: 10.1016/j.cmet.2024.06.013. Epub 2024 Jul 25. Cell Metab. 2024. PMID: 39059384 Free PMC article.
Consensus was achieved for the following terms: "fasting" (voluntary abstinence from some or all foods or foods and beverages), "modified fasting" (restriction of energy intake to max. 25% of energy needs), "fluid-only fasting," "alternate-day fasting, …
Consensus was achieved for the following terms: "fasting" (voluntary abstinence from some or all foods or foods and beverages), "modi …
Fasting: molecular mechanisms and clinical applications.
Longo VD, Mattson MP. Longo VD, et al. Cell Metab. 2014 Feb 4;19(2):181-92. doi: 10.1016/j.cmet.2013.12.008. Epub 2014 Jan 16. Cell Metab. 2014. PMID: 24440038 Free PMC article. Review.
In lower eukaryotes, chronic fasting extends longevity, in part, by reprogramming metabolic and stress resistance pathways. In rodents intermittent or periodic fasting protects against diabetes, cancers, heart disease, and neurodegeneration, while in humans i …
In lower eukaryotes, chronic fasting extends longevity, in part, by reprogramming metabolic and stress resistance pathways. In rodent …
Nutrition, GH/IGF-1 signaling, and cancer.
Fanti M, Longo VD. Fanti M, et al. Endocr Relat Cancer. 2024 Oct 7;31(11):e230048. doi: 10.1530/ERC-23-0048. Print 2024 Nov 1. Endocr Relat Cancer. 2024. PMID: 39166749 Free PMC article. Review.
Given their ability to reduce risk factors, albeit with varying efficacy, nutrition and fasting could help prevent cancer and other age-related disorders. Calorie restriction (CR), various forms of intermittent fasting (IF) or periodic fasting (PF), an …
Given their ability to reduce risk factors, albeit with varying efficacy, nutrition and fasting could help prevent cancer and other a …
Nutrition and dietary restrictions in cancer prevention.
Mishra A, Giuliani G, Longo VD. Mishra A, et al. Biochim Biophys Acta Rev Cancer. 2024 Jan;1879(1):189063. doi: 10.1016/j.bbcan.2023.189063. Epub 2023 Dec 24. Biochim Biophys Acta Rev Cancer. 2024. PMID: 38147966 Review.
In this review, we will discuss how diet and dietary restrictions affect cancer risk and the molecular mechanisms potentially responsible for their effects. We will cover calorie restriction, intermittent fasting, prolonged fasting, fasting-mimicking d …
In this review, we will discuss how diet and dietary restrictions affect cancer risk and the molecular mechanisms potentially responsible fo …
Time-restricted eating effects on performance, immune function, and body composition in elite cyclists: a randomized controlled trial.
Moro T, Tinsley G, Longo G, Grigoletto D, Bianco A, Ferraris C, Guglielmetti M, Veneto A, Tagliabue A, Marcolin G, Paoli A. Moro T, et al. J Int Soc Sports Nutr. 2020 Dec 11;17(1):65. doi: 10.1186/s12970-020-00396-z. J Int Soc Sports Nutr. 2020. PMID: 33308259 Free PMC article. Clinical Trial.
BACKGROUND: Although there is substantial interest in intermittent fasting as a dietary approach in active individuals, information regarding its effects in elite endurance athletes is currently unavailable. The present parallel randomized trial investigated the eff …
BACKGROUND: Although there is substantial interest in intermittent fasting as a dietary approach in active individuals, inform …
Intermittent and periodic fasting, longevity and disease.
Longo VD, Di Tano M, Mattson MP, Guidi N. Longo VD, et al. Nat Aging. 2021 Jan;1(1):47-59. doi: 10.1038/s43587-020-00013-3. Epub 2021 Jan 14. Nat Aging. 2021. PMID: 35310455 Free PMC article.
Intermittent and periodic fasting (IF and PF, respectively) are emerging as safe strategies to affect longevity and healthspan by acting on cellular aging and disease risk factors, while causing no or minor side effects. IF lasting from 12 to 48 hours and repeated e …
Intermittent and periodic fasting (IF and PF, respectively) are emerging as safe strategies to affect longevity and healthspan …
Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology.
Rangan P, Choi I, Wei M, Navarrete G, Guen E, Brandhorst S, Enyati N, Pasia G, Maesincee D, Ocon V, Abdulridha M, Longo VD. Rangan P, et al. Cell Rep. 2019 Mar 5;26(10):2704-2719.e6. doi: 10.1016/j.celrep.2019.02.019. Cell Rep. 2019. PMID: 30840892 Free PMC article.
Dietary interventions are potentially effective therapies for inflammatory bowel diseases (IBDs). We tested the effect of 4-day fasting-mimicking diet (FMD) cycles on a chronic dextran sodium sulfate (DSS)-induced murine model resulting in symptoms and pathology associated …
Dietary interventions are potentially effective therapies for inflammatory bowel diseases (IBDs). We tested the effect of 4-day fasting …
24 results