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Page 1
Did you mean ftoracizine (1 results)?
[Tiracizine in the treatment of ventricular arrhythmia (preliminary study)].
Stejfa M, Zeman K, Groch L, Bytesník J, Krausová R. Stejfa M, et al. Vnitr Lek. 1993 Jun;39(6):549-53. Vnitr Lek. 1993. PMID: 8212608 Czech.
Tiracizine a new antiarrhythmic drug class Ia was tested in a open crossover study in a group of 46 patients with more than 2500 ventricular extrasystoles per 24 hours or with ventricular arrhythmias III or a higher Lown class. ...Side-effects of an anticholinergic type we …
Tiracizine a new antiarrhythmic drug class Ia was tested in a open crossover study in a group of 46 patients with more than 2500 vent …
Pharmacokinetics of the antiarrhythmic agent tiracizine: steady state kinetics in comparison with single-dose kinetics.
Berndt A, Oertel R, Terhaag B, Richter K, Gramatté T. Berndt A, et al. Biopharm Drug Dispos. 1995 Jul;16(5):427-41. doi: 10.1002/bdd.2510160507. Biopharm Drug Dispos. 1995. PMID: 8527691 Clinical Trial.
Serum and urine kinetics of unchanged tiracizine (T), a new class I antiarrhythmic agent, and three metabolites (M1, 2, and 3) were assessed in eight healthy extensive metabolizers after a single oral administration of 50 mg tiracizine and during steady state (50 mg …
Serum and urine kinetics of unchanged tiracizine (T), a new class I antiarrhythmic agent, and three metabolites (M1, 2, and 3) were a …
Dose dependent tiracizine disposition in healthy volunteers: serum and urine kinetics and dose related ECG-changes.
Berndt A, Gramatté T, Oertel R, Richter K, Terhaag B, Kirch W. Berndt A, et al. Eur J Drug Metab Pharmacokinet. 1994 Oct-Dec;19(4):359-68. doi: 10.1007/BF03188863. Eur J Drug Metab Pharmacokinet. 1994. PMID: 7737238 Clinical Trial.
The pharmacokinetics of tiracizine, a new class I antiarrhythmic agent, and 3 of its metabolites were assessed in serum and urine of 8 healthy extensive metabolisers after single oral administration of 50, 100, and 200 mg tiracizine hydrochloride. ...PQ- and QRS-int …
The pharmacokinetics of tiracizine, a new class I antiarrhythmic agent, and 3 of its metabolites were assessed in serum and urine of …
[Electrophysiological anti-arrhythmia effects of tiracizine in ventricular tachycardia].
Volkmann H, Kühnert H, Dannberg G, Heinke M, Leeder U, Popp U. Volkmann H, et al. Z Gesamte Inn Med. 1991 Dec;46(17):635-41. Z Gesamte Inn Med. 1991. PMID: 1776306 German.
In 11 of 13 patients with further inducible VT the cycle duration of VT increased after tiracizine (mean 29 ms). After oral tiracizine (150-225 mg/day) the VT induction was suppressed in one patient. ...Antiarrhythmic efficacy of intravenous or oral tiracizine …
In 11 of 13 patients with further inducible VT the cycle duration of VT increased after tiracizine (mean 29 ms). After oral tiraci …
Food Enhances Bioavailability of the New Antiarrhythmic Agent Tiracizine by Affecting its Hepatic First-Pass Metabolism: Evidence by Serum and Urine Metabolite Kinetics.
Berndt A, Oertel R, Richter K, Gramatté T. Berndt A, et al. Am J Ther. 1994 Jun;1(1):22-29. doi: 10.1097/00045391-199406000-00005. Am J Ther. 1994. PMID: 11835063
The serum and urine kinetics of tiracizine, a new class I antiarrhythmic agent, and three of its metabolites were assessed in eight healthy extensive metabolizers after a single oral administration of 100 mg tiracizine in fasted state and after a standard breakfast. …
The serum and urine kinetics of tiracizine, a new class I antiarrhythmic agent, and three of its metabolites were assessed in eight h …
[Relative bioavailability of the antiarrhythmia agent, tiracizine and its metabolites].
Berndt A, Oertel R, Richter K, Terhaag B, Gramatté T. Berndt A, et al. Arzneimittelforschung. 1995 Mar;45(3):250-3. Arzneimittelforschung. 1995. PMID: 7741778 Clinical Trial. German.
Tiracizine and three of its metabolites (M1, M2 and M3) were measured in serum and urine by high pressure liquid chromatography. ...Mean maximum serum concentrations after the test preparation and corresponding 95% confidence interval were 111.2 ng/ml and 0.86-1.20 for …
Tiracizine and three of its metabolites (M1, M2 and M3) were measured in serum and urine by high pressure liquid chromatography. ...M …
Day-night variations in the renal excretion of the antiarrhythmic agent tiracizine and its metabolites.
Berndt A, Gramatté T, Oertel R, Terhaag B, Richter K, Kirch W. Berndt A, et al. Chronobiol Int. 1995 Apr;12(2):135-40. doi: 10.3109/07420529509064508. Chronobiol Int. 1995. PMID: 8653799
Daytime and nighttime urinary recovery as well as morning and evening trough serum levels of the antiarrhythmic agent tiracizine and three of its metabolites (M1, M2, and M3) were assessed during a 7-day multiple-dose study period (50 mg tiracizine twice daily) in e …
Daytime and nighttime urinary recovery as well as morning and evening trough serum levels of the antiarrhythmic agent tiracizine and …
Determination of drugs in biological fluids by high-performance liquid chromatography with on-line sample processing.
Oertel R, Richter K, Gramatté T, Kirch W. Oertel R, et al. J Chromatogr A. 1998 Feb 27;797(1-2):203-9. doi: 10.1016/s0021-9673(97)00966-7. J Chromatogr A. 1998. PMID: 9542112
An automated two column HPLC system with the new packing material LiChrospher RP-18 ADS (alkyl-diol-silica) was tested for the determination of several drugs and metabolites (talinolol, celiprolol, metoprolol, oxprenolol, triamterene, trimethoprim, tiracizine, articaine, d …
An automated two column HPLC system with the new packing material LiChrospher RP-18 ADS (alkyl-diol-silica) was tested for the determination …
66 results