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Page 1
The Roles of Vitamin C in Skin Health.
Pullar JM, Carr AC, Vissers MCM. Pullar JM, et al. Nutrients. 2017 Aug 12;9(8):866. doi: 10.3390/nu9080866. Nutrients. 2017. PMID: 28805671 Free PMC article. Review.
Normal skin contains high concentrations of vitamin C, which supports important and well-known functions, stimulating collagen synthesis and assisting in antioxidant protection against UV-induced photodamage. ...This review discusses the potential roles for vitamin …
Normal skin contains high concentrations of vitamin C, which supports important and well-known functions, stimulating collagen …
Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo.
Humbert PG, Haftek M, Creidi P, Lapière C, Nusgens B, Richard A, Schmitt D, Rougier A, Zahouani H. Humbert PG, et al. Exp Dermatol. 2003 Jun;12(3):237-44. doi: 10.1034/j.1600-0625.2003.00008.x. Exp Dermatol. 2003. PMID: 12823436 Free article. Clinical Trial.
Vitamin C is known for its antioxidant potential and activity in the collagen biosynthetic pathway. Photoprotective properties of topically applied vitamin C have also been demonstrated, placing this molecule as a potential candidate for use in the prevention and tr …
Vitamin C is known for its antioxidant potential and activity in the collagen biosynthetic pathway. Photoprotective properties of …
Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications.
Al-Niaimi F, Chiang NYZ. Al-Niaimi F, et al. J Clin Aesthet Dermatol. 2017 Jul;10(7):14-17. Epub 2017 Jul 1. J Clin Aesthet Dermatol. 2017. PMID: 29104718 Free PMC article. Review.
OBJECTIVE: This review article details the main mechanisms of action and clinical applications of topical vitamin C on the skin, including its antioxidative, photoprotective, antiaging, and antipigmentary effects. DESIGN: A PubMed search for the relevant articles on …
OBJECTIVE: This review article details the main mechanisms of action and clinical applications of topical vitamin C on the skin …
A review of topical vitamin C derivatives and their efficacy.
Enescu CD, Bedford LM, Potts G, Fahs F. Enescu CD, et al. J Cosmet Dermatol. 2022 Jun;21(6):2349-2359. doi: 10.1111/jocd.14465. Epub 2021 Sep 24. J Cosmet Dermatol. 2022. PMID: 34559950 Review.
Vitamin C is a popular ingredient in over-the-counter cosmeceuticals due to its many biological functions in maintaining and improving skin health by treating UV damage, improving discoloration, and boosting collagen production. Several chemically modified derivativ …
Vitamin C is a popular ingredient in over-the-counter cosmeceuticals due to its many biological functions in maintaining and improving sk …
Antioxidants for Skin Health.
Kumar V, Tanwar N, Goel M, Khan M, Kumar D, Singh G, Mundlia J, Khatri N, Kumar A. Kumar V, et al. Recent Adv Food Nutr Agric. 2025;16(3):250-265. doi: 10.2174/012772574X311177240710100118. Recent Adv Food Nutr Agric. 2025. PMID: 39108105 Review.
This paper reviews the contributions of key antioxidants, including Vitamin C, Vitamin E, Vitamin A, green tea extract, Coenzyme Q10, Resveratrol, Selenium, and Polyphenols, in skin health care. Vitamin C, known for its collagen synthesis promotion and photoprotecti …
This paper reviews the contributions of key antioxidants, including Vitamin C, Vitamin E, Vitamin A, green tea extract, Coenzyme Q10, Resver …
Efficacy of topical vitamin C in melasma and photoaging: A systematic review.
Correia G, Magina S. Correia G, et al. J Cosmet Dermatol. 2023 Jul;22(7):1938-1945. doi: 10.1111/jocd.15748. Epub 2023 May 2. J Cosmet Dermatol. 2023. PMID: 37128827
BACKGROUND: Vitamin C is a micronutrient present in high concentrations in normal skin and a highly prescribed cosmeceutical, well known for protecting against ultraviolet-induced pigmentation and regulating collagen production. ...Studies that evaluated the topogra …
BACKGROUND: Vitamin C is a micronutrient present in high concentrations in normal skin and a highly prescribed cosmeceutical, well kn …
Topical Application of Ascorbic Acid and its Derivatives: A Review Considering Clinical Trials.
Vasques LI, Vendruscolo CW, Leonardi GR. Vasques LI, et al. Curr Med Chem. 2023;30(29):3272-3286. doi: 10.2174/0929867329666221003102238. Curr Med Chem. 2023. PMID: 36200216 Review.
METHODS: A literature review was carried out to select studies that evaluated the topical use of ascorbic acid and/or its derivatives. The studies which are "fully available", "in vivo" and "in vitro", were used as inclusion criteria. ...CONCLUSION: Studies o …
METHODS: A literature review was carried out to select studies that evaluated the topical use of ascorbic acid and/or i …
In vivo evaluation of topical ascorbic acid application on skin aging by 50 MHz ultrasound.
Vergilio MM, Aiello LM, Furlan AS, Caritá AC, Azevedo JR, Bolzinger MA, Chevalier Y, Leonardi GR. Vergilio MM, et al. J Cosmet Dermatol. 2022 Oct;21(10):4921-4926. doi: 10.1111/jocd.14892. Epub 2022 Mar 14. J Cosmet Dermatol. 2022. PMID: 35238148
INTRODUCTION: Ascorbic acid (AA) is a powerful antioxidant capable of acting significantly both in the prevention and treatment of the skin aging process. ...RESULTS: A significant increase in total skin and dermal echogenicity was observed after to …
INTRODUCTION: Ascorbic acid (AA) is a powerful antioxidant capable of acting significantly both in the prevention and treatmen …
A Mixture of Topical Forms of Polydeoxyribonucleotide, Vitamin C, and Niacinamide Attenuated Skin Pigmentation and Increased Skin Elasticity by Modulating Nuclear Factor Erythroid 2-like 2.
Kim HM, Byun KA, Oh S, Yang JY, Park HJ, Chung MS, Son KH, Byun K. Kim HM, et al. Molecules. 2022 Feb 14;27(4):1276. doi: 10.3390/molecules27041276. Molecules. 2022. PMID: 35209068 Free PMC article.
It is well-known that increased oxidative stress caused by ultraviolet B (UV-B) radiation induces melanogenesis and activates metalloproteinases (MMPs), which degrade collagen and elastin fibers, leading to decreased skin elasticity. Various antioxidant agents, such …
It is well-known that increased oxidative stress caused by ultraviolet B (UV-B) radiation induces melanogenesis and activates metalloprotein …
Topical delivery of l-ascorbic acid spanlastics for stability enhancement and treatment of UVB induced damaged skin.
Elhabak M, Ibrahim S, Abouelatta SM. Elhabak M, et al. Drug Deliv. 2021 Dec;28(1):445-453. doi: 10.1080/10717544.2021.1886377. Drug Deliv. 2021. PMID: 33620008 Free PMC article. Clinical Trial.
l-Ascorbic acid (LAA) is considered a powerful antioxidant that protects skin from premature aging. ...LAA-loaded spanlastics successfully improved LAA stability, skin permeation and antioxidant protection against skin photodamage....
l-Ascorbic acid (LAA) is considered a powerful antioxidant that protects skin from premature aging. ...LAA-loaded spanl …
81 results