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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
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1948 12
1949 16
1950 29
1951 51
1952 116
1953 39
1954 32
1955 37
1956 38
1957 37
1958 53
1959 52
1960 42
1961 57
1962 72
1963 95
1964 123
1965 138
1966 140
1967 179
1968 269
1969 253
1970 239
1971 252
1972 279
1973 292
1974 316
1975 426
1976 392
1977 445
1978 405
1979 450
1980 459
1981 485
1982 496
1983 507
1984 524
1985 542
1986 551
1987 519
1988 503
1989 559
1990 574
1991 523
1992 539
1993 616
1994 561
1995 620
1996 584
1997 606
1998 665
1999 672
2000 729
2001 759
2002 882
2003 850
2004 856
2005 818
2006 918
2007 1001
2008 1060
2009 1111
2010 1102
2011 1221
2012 1225
2013 1350
2014 1342
2015 1327
2016 1350
2017 1426
2018 1380
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44,929 results

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Page 1
Trace Element Deficiency in Systemic Sclerosis-Too Much Effort for Some Traces?
Opriș-Belinski D, Cobilinschi CO, Caraiola S, Ungureanu R, Cotae AM, Grințescu IM, Cobilinschi C, Andrei AC, Țincu R, Ene R, Mirea L. Opriș-Belinski D, et al. Nutrients. 2024 Jun 27;16(13):2053. doi: 10.3390/nu16132053. Nutrients. 2024. PMID: 38999801 Free PMC article. Review.
Trace elements are essential for several physiological processes. To date, various data have suggested that inadequate levels of trace elements may be involved in the pathogenesis of different chronic diseases, including immune-mediated ones, or may de …
Trace elements are essential for several physiological processes. To date, various data have suggested that inadequate levels …
Trace element deficiency and toxicity.
Van Gossum A, Neve J. Van Gossum A, et al. Curr Opin Clin Nutr Metab Care. 1998 Nov;1(6):499-507. doi: 10.1097/00075197-199811000-00004. Curr Opin Clin Nutr Metab Care. 1998. PMID: 10565401 Review.
Some groups of individuals are more likely to develop trace element deficiency. The role of trace elements deficiency is suspected in various clinical situations and is now confirmed by well designed supplementation studies. ...Recent dat …
Some groups of individuals are more likely to develop trace element deficiency. The role of trace elements …
Zinc Toxicity: Understanding the Limits.
Schoofs H, Schmit J, Rink L. Schoofs H, et al. Molecules. 2024 Jul 1;29(13):3130. doi: 10.3390/molecules29133130. Molecules. 2024. PMID: 38999082 Free PMC article. Review.
Zinc, a vital trace element, holds significant importance in numerous physiological processes within the body. It participates in over 300 enzymatic reactions, metabolic functions, regulation of gene expression, apoptosis and immune modulation, thereby demonstrating …
Zinc, a vital trace element, holds significant importance in numerous physiological processes within the body. It participates …
Copper Deficiency: Causes, Manifestations, and Treatment.
Altarelli M, Ben-Hamouda N, Schneider A, Berger MM. Altarelli M, et al. Nutr Clin Pract. 2019 Aug;34(4):504-513. doi: 10.1002/ncp.10328. Epub 2019 Jun 17. Nutr Clin Pract. 2019. PMID: 31209935 Review.
BACKGROUND: The metabolism of the essential trace element copper remains incompletely understood and, until recently, nearly ignored in acute medicine. ...METHOD AND RESULTS: A review of literature was conducted in PubMed and Cochrane systematic reviews to identify …
BACKGROUND: The metabolism of the essential trace element copper remains incompletely understood and, until recently, nearly i …
Obesity, malnutrition, and trace element deficiency in the coronavirus disease (COVID-19) pandemic: An overview.
Fedele D, De Francesco A, Riso S, Collo A. Fedele D, et al. Nutrition. 2021 Jan;81:111016. doi: 10.1016/j.nut.2020.111016. Epub 2020 Sep 8. Nutrition. 2021. PMID: 33059127 Free PMC article. Review.
Systemic inflammation, immune system impairment, sarcopenia, and preexisting associated conditions, such as respiratory, cardiovascular, and metabolic diseases related to obesity, could act as crucial factors linking nutritional status and the course and outcome of COVID-19. Neve …
Systemic inflammation, immune system impairment, sarcopenia, and preexisting associated conditions, such as respiratory, cardiovascular, and …
Trace Element Deficiency in Axial Spondyloarthritis and Psoriatic Arthritis in Relation to Markers of Inflammation and Remission.
Gröber U, Tsiami S, Chillon TS, Rousis E, Kisters K, Karmeli S, Kiltz U, Schomburg L, Baraliakos X. Gröber U, et al. Int J Mol Sci. 2025 May 21;26(10):4924. doi: 10.3390/ijms26104924. Int J Mol Sci. 2025. PMID: 40430066 Free PMC article.
Copper (Cu) and zinc (Zn) are integral components of key enzymes and regulatory proteins. Trace element (TE) dysregulations have potential relevance as disease biomarkers. In this study, we compare TE status and TE profiles between patients with axial spondyloarthri …
Copper (Cu) and zinc (Zn) are integral components of key enzymes and regulatory proteins. Trace element (TE) dysregulations ha …
A.S.P.E.N. position paper: recommendations for changes in commercially available parenteral multivitamin and multi-trace element products.
Vanek VW, Borum P, Buchman A, Fessler TA, Howard L, Jeejeebhoy K, Kochevar M, Shenkin A, Valentine CJ; Novel Nutrient Task Force, Parenteral Multi-Vitamin and Multi–Trace Element Working Group; American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) Board of Directors. Vanek VW, et al. Nutr Clin Pract. 2012 Aug;27(4):440-91. doi: 10.1177/0884533612446706. Epub 2012 Jun 22. Nutr Clin Pract. 2012. PMID: 22730042
Choline should also be routinely added to adult and pediatric PN formulations; however, a commercially available parenteral product needs to be developed. The parenteral multi-trace element (TE) preparations that are commercially available in the U.S. require signif …
Choline should also be routinely added to adult and pediatric PN formulations; however, a commercially available parenteral product needs to …
Trace element deficiency is highly prevalent and associated with infection and mortality in patients with alcoholic hepatitis.
Dhanda A, Atkinson S, Vergis N, Enki D, Fisher A, Clough R, Cramp M, Thursz M. Dhanda A, et al. Aliment Pharmacol Ther. 2020 Aug;52(3):537-544. doi: 10.1111/apt.15880. Epub 2020 Jun 23. Aliment Pharmacol Ther. 2020. PMID: 32573823
The prevalence and relevance of trace element deficiency is unknown in alcoholic hepatitis. AIM: To determine the prevalence of trace element deficiency and its association with clinical outcomes in patients with alcoholic hepatitis. ...C …
The prevalence and relevance of trace element deficiency is unknown in alcoholic hepatitis. AIM: To determine the preva …
Trace element-gene interactions.
Chesters JK. Chesters JK. Nutr Rev. 1992 Aug;50(8):217-23. doi: 10.1111/j.1753-4887.1992.tb01331.x. Nutr Rev. 1992. PMID: 1407752 Review.
For many of the genes encoding proteins involved in the transport, storage, and function of the trace elements, expression is regulated by the availability of the elements concerned. ...In addition, the sensitivity of growth and fetal development to the lack …
For many of the genes encoding proteins involved in the transport, storage, and function of the trace elements, expression is …
44,929 results
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