Topical L-ascorbic acid: percutaneous absorption studies.
Pinnell SR, Yang H, Omar M, Monteiro-Riviere N, DeBuys HV, Walker LC, Wang Y, Levine M.
Pinnell SR, et al.
Dermatol Surg. 2001 Feb;27(2):137-42. doi: 10.1046/j.1524-4725.2001.00264.x.
Dermatol Surg. 2001.
PMID: 11207686
Maximal concentration for optimal percutaneous absorption was 20%. Tissue levels were saturated after three daily applications; the half-life of tissue disappearance was about 4 days. Derivatives of ascorbic acid including magnesium ascorbyl phosphate, ascorbyl-6-pa …
Maximal concentration for optimal percutaneous absorption was 20%. Tissue levels were saturated after three daily applications; the h …