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Page 1
Did you mean ransmembrane signalling receptor activity (398,939 results)?
Structure-activity relationships for transmembrane signaling: the receptor's turn.
Hollenberg MD. Hollenberg MD. FASEB J. 1991 Feb;5(2):178-86. doi: 10.1096/fasebj.5.2.1848518. FASEB J. 1991. PMID: 1848518 Review.
The three basic mechanisms of receptor-mediated transmembrane signaling (ligand-regulated ion flux; ligand-regulated receptor-enzymes; ligand-regulated receptor-G protein activation) can now be placed in the structural context of at least …
The three basic mechanisms of receptor-mediated transmembrane signaling (ligand-regulated ion flux; ligand-regulated …
Cracking the BAFF code.
Mackay F, Schneider P. Mackay F, et al. Nat Rev Immunol. 2009 Jul;9(7):491-502. doi: 10.1038/nri2572. Nat Rev Immunol. 2009. PMID: 19521398 Free article. Review.
The tumour necrosis factor (TNF) family members B cell activating factor (BAFF) and APRIL (a proliferation-inducing ligand) are crucial survival factors for peripheral B cells. ...In this Review, we consider the possibility that in mice autoimmunity induced by BAFF is link …
The tumour necrosis factor (TNF) family members B cell activating factor (BAFF) and APRIL (a proliferation-inducing ligand) are cruci …
Seven-transmembrane receptor signaling through beta-arrestin.
Shenoy SK, Lefkowitz RJ. Shenoy SK, et al. Sci STKE. 2005 Nov 1;2005(308):cm10. doi: 10.1126/stke.2005/308/cm10. Sci STKE. 2005. PMID: 16267056 Review.
The largest receptor family is the seven-transmembrane receptor (7TMR) family, with approximately 1000 coding genes in the human genome. ...Activated receptors are rapidly phosphorylated on serine and threonine residues by specialized enzymes ca …
The largest receptor family is the seven-transmembrane receptor (7TMR) family, with approximately 1000 coding genes in …
Transmembrane signaling by a synthetic receptor in artificial cells.
Søgaard AB, Pedersen AB, Løvschall KB, Monge P, Jakobsen JH, Džabbarova L, Nielsen LF, Stevanovic S, Walther R, Zelikin AN. Søgaard AB, et al. Nat Commun. 2023 Mar 24;14(1):1646. doi: 10.1038/s41467-023-37393-0. Nat Commun. 2023. PMID: 36964156 Free PMC article.
The main difference from natural receptors is the mechanism of signal transduction, which is achieved using a self-immolative linker. ...We demonstrate an artificial signaling cascade that achieves transmembrane enzyme activation, a hallm …
The main difference from natural receptors is the mechanism of signal transduction, which is achieved using a self-immo …
Agonist-trafficking and hallucinogens.
González-Maeso J, Sealfon SC. González-Maeso J, et al. Curr Med Chem. 2009;16(8):1017-27. doi: 10.2174/092986709787581851. Curr Med Chem. 2009. PMID: 19275609 Review.
Seven transmembrane domain receptors, also termed G protein-coupled receptors (GPCRs), represent the most common molecular target for therapeutic drugs. ...According to this agonist- trafficking model, agonists stabilize distinct activated receptor …
Seven transmembrane domain receptors, also termed G protein-coupled receptors (GPCRs), represent the most common molecu …
Platelet-activating factor receptor.
Ishii S, Nagase T, Shimizu T. Ishii S, et al. Prostaglandins Other Lipid Mediat. 2002 Aug;68-69:599-609. doi: 10.1016/s0090-6980(02)00058-8. Prostaglandins Other Lipid Mediat. 2002. PMID: 12432946 Review.
Platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is a biologically active phospholipid mediator. ...PAF acts by binding to a unique G-protein-coupled seven transmembrane receptor, and activates multiple intracellu …
Platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is a biologically active phospholipid mediato …
Interferon signal transduction.
Larner A, Reich NC. Larner A, et al. Biotherapy. 1996;8(3-4):175-81. doi: 10.1007/BF01877202. Biotherapy. 1996. PMID: 8813329 Review.
The interferon signal transduction pathway initiates at a cell surface receptor and mediates the activation of target genes in the nucleus. ...Advances in the field of interferon research have contributed to our understanding of signal transd …
The interferon signal transduction pathway initiates at a cell surface receptor and mediates the activation of t …
Transmembrane signaling through single-spanning receptors modulated by phase separation at the cell surface.
Murai T. Murai T. Eur J Cell Biol. 2024 Jun;103(2):151413. doi: 10.1016/j.ejcb.2024.151413. Epub 2024 Apr 12. Eur J Cell Biol. 2024. PMID: 38631097 Free article. Review.
A wide variety of transmembrane signals are transduced by cell-surface receptors that activate intracellular signaling molecules. ...This study describes the emerging features of transmembrane signaling through single-spanning r …
A wide variety of transmembrane signals are transduced by cell-surface receptors that activate intracellular …
Non-Smad signaling pathways.
Mu Y, Gudey SK, Landström M. Mu Y, et al. Cell Tissue Res. 2012 Jan;347(1):11-20. doi: 10.1007/s00441-011-1201-y. Epub 2011 Jun 24. Cell Tissue Res. 2012. PMID: 21701805 Review.
TGFbeta also uses non-Smad signaling pathways such as the p38 and Jun N-terminal kinase (JNK) mitogen-activated protein kinase (MAPK) pathways to convey its signals. ...Signals induced by TGFbeta are tightly regulated and specified by post-translationa …
TGFbeta also uses non-Smad signaling pathways such as the p38 and Jun N-terminal kinase (JNK) mitogen-activated protein kinase …
Signals and Receptors.
Heldin CH, Lu B, Evans R, Gutkind JS. Heldin CH, et al. Cold Spring Harb Perspect Biol. 2016 Apr 1;8(4):a005900. doi: 10.1101/cshperspect.a005900. Cold Spring Harb Perspect Biol. 2016. PMID: 27037414 Free PMC article. Review.
Signaling receptors can be single-span plasma membrane receptors associated with tyrosine or serine/threonine kinase activities, proteins with seven transmembrane domains, or intracellular receptors. Ligand-activated receptors …
Signaling receptors can be single-span plasma membrane receptors associated with tyrosine or serine/threonine kinase …
14,364 results
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