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Page 1
Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer.
Zlinska V, Feketova Z, Czyrek A, Chudzian J, Zivkovic ML, Ursachi VC, Dudeja P, Fafilek B, Rynes J, Rico-Llanos G, Koudelka A, Roy T, Biadun M, Raskova V, Svozilova K, Stroblova M, Krzyscik M, Hristova K, Krowarsch D, Foldynova-Trantirkova S, Zakrzewska M, Trantirek L, Krejci P. Zlinska V, et al. Mol Ther Nucleic Acids. 2024 Nov 28;36(1):102405. doi: 10.1016/j.omtn.2024.102405. eCollection 2025 Mar 11. Mol Ther Nucleic Acids. 2024. PMID: 39759879 Free PMC article.
The future of integrated structural biology.
Schwalbe H, Audergon P, Haley N, Amaro CA, Agirre J, Baldus M, Banci L, Baumeister W, Blackledge M, Carazo JM, Carugo KD, Celie P, Felli I, Hart DJ, Hauß T, Lehtiö L, Lindorff-Larsen K, Márquez J, Matagne A, Pierattelli R, Rosato A, Sobott F, Sreeramulu S, Steyaert J, Sussman JL, Trantirek L, Weiss MS, Wilmanns M. Schwalbe H, et al. Structure. 2024 Oct 3;32(10):1563-1580. doi: 10.1016/j.str.2024.08.014. Epub 2024 Sep 17. Structure. 2024. PMID: 39293444 Free article. Review.
Structural Optimization of Azacryptands for Targeting Three-Way DNA Junctions.
Pipier A, Chetot T, Kalamatianou A, Martin N, Caroff M, Britton S, Chéron N, Trantírek L, Granzhan A, Monchaud D. Pipier A, et al. Angew Chem Int Ed Engl. 2024 Sep 2;63(36):e202409780. doi: 10.1002/anie.202409780. Epub 2024 Aug 1. Angew Chem Int Ed Engl. 2024. PMID: 38873877
In-cell NMR suggests that DNA i-motif levels are strongly depleted in living human cells.
Víšková P, Ištvánková E, Ryneš J, Džatko Š, Loja T, Živković ML, Rigo R, El-Khoury R, Serrano-Chacón I, Damha MJ, González C, Mergny JL, Foldynová-Trantírková S, Trantírek L. Víšková P, et al. Nat Commun. 2024 Mar 5;15(1):1992. doi: 10.1038/s41467-024-46221-y. Nat Commun. 2024. PMID: 38443388 Free PMC article.
DNA Quadruplex Structure with a Unique Cation Dependency.
Gajarsky M, Stadlbauer P, Sponer J, Cucchiarini A, Dobrovolna M, Brazda V, Mergny JL, Trantirek L, Lenarcic Zivkovic M. Gajarsky M, et al. Angew Chem Int Ed Engl. 2024 Feb 12;63(7):e202313226. doi: 10.1002/anie.202313226. Epub 2024 Jan 15. Angew Chem Int Ed Engl. 2024. PMID: 38143239
A sodium/potassium switch for G4-prone G/C-rich sequences.
Luo Y, Živković ML, Wang J, Ryneš J, Foldynová-Trantírková S, Trantírek L, Verga D, Mergny JL. Luo Y, et al. Nucleic Acids Res. 2024 Jan 11;52(1):448-461. doi: 10.1093/nar/gkad1073. Nucleic Acids Res. 2024. PMID: 37986223 Free PMC article.
Last year at Marienbad: Unusual nucleic acid structures.
Mergny JL, Trantírek L, Capranico G. Mergny JL, et al. Biochimie. 2023 Nov;214(Pt A):1-4. doi: 10.1016/j.biochi.2023.09.022. Epub 2023 Sep 23. Biochimie. 2023. PMID: 37748749 No abstract available.
DNA i-motif formation at neutral pH is driven by kinetic partitioning.
Školáková P, Gajarský M, Palacký J, Šubert D, Renčiuk D, Trantírek L, Mergny JL, Vorlíčková M. Školáková P, et al. Nucleic Acids Res. 2023 Apr 11;51(6):2950-2962. doi: 10.1093/nar/gkad119. Nucleic Acids Res. 2023. PMID: 36912102 Free PMC article.
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