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Year Number of Results
1988 1
1989 3
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1992 1
1993 1
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1995 3
1996 9
1997 4
1998 5
1999 2
2000 5
2001 9
2002 7
2003 6
2004 16
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2006 3
2007 18
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2012 26
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651 results

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Page 1
New Allosteric Modulators of Molecular Chaperone TRAP1 from the Integration of Computational Biology, Medicinal Chemistry, and Biophysics.
Guarra F, Komarov D, Ciamarone A, Torielli L, Previtali V, Margaroli N, Romeo E, La Spina M, Sbuelz F, Laquatra C, Veronesi M, Lolicato M, Arrigoni C, Moroni E, Serapian SA, Girotto S, Rasola A, Colombo G. Guarra F, et al. Cell Stress Chaperones. 2026 Feb 25:100162. doi: 10.1016/j.cstres.2026.100162. Online ahead of print. Cell Stress Chaperones. 2026. PMID: 41759775 Free article. Review.
Here, we exploit the intrinsic asymmetry of mitochondrial isoform TRAP1 and combine it with a fragment-design inspired approach to develop new possible TRAP1 targeting leads. We start from the consideration that TRAP1 catalytic cycle relies on a strained, asy …
Here, we exploit the intrinsic asymmetry of mitochondrial isoform TRAP1 and combine it with a fragment-design inspired approach to de …
SCMO: a deep learning model integrating the single-cell resolution TME ecosystem and multi-omics for survival prediction in CRC patients.
He Z, Fan X, Li Y, Li Q, Bu D, Han A, Guo JC, Liu J, Mao H, Dai X, Zhao Y. He Z, et al. J Transl Med. 2026 Feb 19;24(1):281. doi: 10.1186/s12967-025-07417-y. J Transl Med. 2026. PMID: 41715092 Free PMC article.
We performed anticancer drug screening with tumor necrosis factor receptor-associated protein 1 (TRAP1), a critical feature according to the Integrated Gradients algorithm, as a potential target. ...TME features from the SCMO model revealed that ecosystem density increased …
We performed anticancer drug screening with tumor necrosis factor receptor-associated protein 1 (TRAP1), a critical feature according …
KDM6A alternative splicing induced by 25(OH)D inhibits breast cancer cell stemness through repressing TRAP1 transcription.
Ma L, Sheng X, Wang L, Wan X, Chen R, Li X, Zheng R, Xu L, Zha X, Wang J. Ma L, et al. Oncogene. 2026 Mar;45(10):914-929. doi: 10.1038/s41388-026-03694-z. Epub 2026 Feb 17. Oncogene. 2026. PMID: 41703283
Mechanistically, CUT&Tag and RNA-seq analyses demonstrated that KDM6A deltaexon13 induces the accumulation of H3K27me3 at the promoter region of TRAP1, thereby inhibiting its transcription. Consequently, the downregulation of TRAP1 reduces Smad2/3 phosphorylatio …
Mechanistically, CUT&Tag and RNA-seq analyses demonstrated that KDM6A deltaexon13 induces the accumulation of H3K27me3 at the promoter r …
Complexity of Infection and Plasmodium falciparum Circumsporozoite Protein Diversity Prior to Malaria Vaccine Implementation in Kaelé Health District, Cameroon, 2022-2023.
Ali IM, Martinez BV, Tchuenkam VPK, Sadler JM, Gorman CC, Nsango SE, Voundi V, Marcellin AJ, Wanda GY, Bailey JA, Dinglasan RR, Lin JT, Juliano JJ. Ali IM, et al. medRxiv [Preprint]. 2026 Jan 19:2026.01.17.26344325. doi: 10.64898/2026.01.17.26344325. medRxiv. 2026. PMID: 41646681 Free PMC article. Preprint.
COI was highest for ama (mean COI = 2.8), followed by sera2 (2.1), csp (1.3), and trap (1.2). This study provides a baseline of P. falciparum antigenic diversity and COI in a vaccine-targeted region. ...
COI was highest for ama (mean COI = 2.8), followed by sera2 (2.1), csp (1.3), and trap (1.2). This study provides a baseline o …
Inhibition of TRAP1 in the C-terminal domain influences mitochondria properties and breast cancer cell metabolism.
Mathieu C, Branco JR, Zancan P, Brenner C, Messaoudi S, Fattal E, Vergnaud J. Mathieu C, et al. Biomed Pharmacother. 2026 Mar;196:119060. doi: 10.1016/j.biopha.2026.119060. Epub 2026 Feb 2. Biomed Pharmacother. 2026. PMID: 41633252 Free article.
Furthermore, the chaperone machinery is affected with a decrease of HSF1 and HSP70, but without degradation of HSP90 or TRAP1, while decreasing the levels of SDH-A and/or SDH-B, partner of TRAP1. Finally, short-term treatments (1 and 3 h) with 6BrCaQ-C(10)-TPP modif …
Furthermore, the chaperone machinery is affected with a decrease of HSF1 and HSP70, but without degradation of HSP90 or TRAP1, while …
Optimizing ovitrap design: the role of ovistrip texture, colour, and water in modulating oviposition behavior of Aedes vector mosquitoes.
Perera APS, Bandaranayaka KO, Marasinghe MMSMB, Weerakoon SN, Jayasooriya HTR. Perera APS, et al. Trop Biomed. 2025 Dec 1;42(4):459-466. doi: 10.47665/tb.42.4.012. Trop Biomed. 2025. PMID: 41619246
A significant effect of ovistrip type (F=6.73, P<0.001) was found on OI and mean egg per trap (F=9.85, P<0.001), where filter paper exhibited the largest coefficient in magnitude (-0.1698), indicating a strong negative correlation with OI and mean eggs per trap (-2.445) whi …
A significant effect of ovistrip type (F=6.73, P<0.001) was found on OI and mean egg per trap (F=9.85, P<0.001), where filter paper ex …
LncRNA ZFAS1 Promotes Alveolar Bone Resorption by Enhancing Osteoclastogenesis in Periodontitis.
Aol L, Zhou X, Cao Z, Yao D, Zhang W, Yang Y, Bao Z, Su L, Hao H, Xue W. Aol L, et al. J Cell Physiol. 2026 Jan;241(1):e70134. doi: 10.1002/jcp.70134. J Cell Physiol. 2026. PMID: 41549697
Notably, ZFAS1 expression showed a robust positive correlation with early osteoclast marker genes NFATC1 (R(2) = 0.2056, p = 0.015) and TRAP1 (R(2) = 0.784, p < 0.0001) but not the late-stage effector CTSK (R(2) = 0.0011, p = 0.792). ...
Notably, ZFAS1 expression showed a robust positive correlation with early osteoclast marker genes NFATC1 (R(2) = 0.2056, p = 0.015) and T …
Comprehensive pan-cancer analysis of TRAP1 and its experimental validation in hepatocellular carcinoma.
Shan S, Wang T, Sun F, Zhao L, Liang S, Wang Z. Shan S, et al. Discov Oncol. 2025 Dec 20;17(1):152. doi: 10.1007/s12672-025-04238-9. Discov Oncol. 2025. PMID: 41422190 Free PMC article.
Nevertheless, comprehensive bioinformatic analyses of TRAP1 across diverse cancer types are limited. Herein, we analyzed TRAP1 across all cancer types, focusing on its expression in relation to prognosis, immune infiltration, and the mammalian target of rapamycin an …
Nevertheless, comprehensive bioinformatic analyses of TRAP1 across diverse cancer types are limited. Herein, we analyzed TRAP1 …
651 results