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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1969 4
1971 1
1973 1
1974 1
1976 2
1977 1
1989 2
1990 2
1994 2
1996 2
1997 1
1999 2
2000 2
2001 1
2003 1
2004 3
2006 2
2007 2
2008 7
2009 5
2010 6
2011 9
2012 5
2013 8
2014 6
2015 7
2016 6
2017 9
2018 12
2019 11
2020 14
2021 9
2022 19
2023 17
2024 19
2025 24
2026 12

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203 results

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Page 1
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Roberts I, Shakur H, Coats T, Hunt B, Balogun E, Barnetson L, Cook L, Kawahara T, Perel P, Prieto-Merino D, Ramos M, Cairns J, Guerriero C. Roberts I, et al. Health Technol Assess. 2013 Mar;17(10):1-79. doi: 10.3310/hta17100. Health Technol Assess. 2013. PMID: 23477634 Free PMC article. Clinical Trial.
MAIN OUTCOME MEASURES: The primary outcome was death in hospital within 4 weeks of injury, and was described with the following categories: bleeding, vascular occlusion (myocardial infarction, stroke and pulmonary embolism), multiorgan failure, head injury …
MAIN OUTCOME MEASURES: The primary outcome was death in hospital within 4 weeks of injury, and was described with the following categ …
Severe Traumatic Brain Injury and Pulmonary Embolism: Risks, Prevention, Diagnosis and Management.
Vrettou CS, Dima E, Karela NR, Sigala I, Korfias S. Vrettou CS, et al. J Clin Med. 2024 Aug 2;13(15):4527. doi: 10.3390/jcm13154527. J Clin Med. 2024. PMID: 39124793 Free PMC article. Review.
Severe traumatic brain injury (sTBI) is a silent epidemic, causing approximately 300,000 intensive care unit (ICU) admissions annually, with a 30% mortality rate. ...We searched PubMed and Scopus for papers published in the last five years that included the t …
Severe traumatic brain injury (sTBI) is a silent epidemic, causing approximately 300,000 intensive care unit (ICU) admi …
Intracranial pressure monitoring with and without brain tissue oxygen pressure monitoring for severe traumatic brain injury in France (OXY-TC): an open-label, randomised controlled superiority trial.
Payen JF, Launey Y, Chabanne R, Gay S, Francony G, Gergele L, Vega E, Montcriol A, Couret D, Cottenceau V, Pili-Floury S, Gakuba C, Hammad E, Audibert G, Pottecher J, Dahyot-Fizelier C, Abdennour L, Gauss T, Richard M, Vilotitch A, Bosson JL, Bouzat P; OXY-TC trial collaborators. Payen JF, et al. Lancet Neurol. 2023 Nov;22(11):1005-1014. doi: 10.1016/S1474-4422(23)00290-9. Lancet Neurol. 2023. PMID: 37863590 Clinical Trial.
INTERPRETATION: After severe non-penetrating traumatic brain injury, intracranial pressure and PbtO(2) monitoring did not reduce the proportion of patients with poor neurological outcome at 6 months. ...Further research is needed to assess whether a targeted …
INTERPRETATION: After severe non-penetrating traumatic brain injury, intracranial pressure and PbtO(2) monitoring did n …
Challenges in Pulmonary Management after Traumatic Brain and Spinal Cord Injury.
Zhou X, Bates AH, Hoffer A. Zhou X, et al. Neurosurg Clin N Am. 2025 Jul;36(3):355-364. doi: 10.1016/j.nec.2025.03.004. Epub 2025 Apr 28. Neurosurg Clin N Am. 2025. PMID: 40543944 Review.
Pulmonary complications after traumatic injuries of the brain and spinal cord are common and can significantly worsen patient outcomes. ...This article reviews the pathophysiology and treatment of lung injuries and other pulmonary …
Pulmonary complications after traumatic injuries of the brain and spinal cord are common and can significantly w …
Therapeutic anticoagulation in patients with traumatic brain injuries and pulmonary emboli.
Chipman AM, Radowsky J, Vesselinov R, Chow D, Schwartzbauer G, Tesoriero R, Stein D. Chipman AM, et al. J Trauma Acute Care Surg. 2020 Sep;89(3):529-535. doi: 10.1097/TA.0000000000002805. J Trauma Acute Care Surg. 2020. PMID: 32467467
Early AC was defined as within 7 days of injury or less; late was defined as after 7 days. Primary outcomes included death, interventions for worsening ICH following AC, and pulmonary complications. Multivariate logistic regression was used to evaluate for clinical …
Early AC was defined as within 7 days of injury or less; late was defined as after 7 days. Primary outcomes included death, intervent …
Pulmonary embolism in severe traumatic brain injury.
Seifi A, Dengler B, Martinez P, Godoy DA. Seifi A, et al. J Clin Neurosci. 2018 Nov;57:46-50. doi: 10.1016/j.jocn.2018.08.042. Epub 2018 Aug 25. J Clin Neurosci. 2018. PMID: 30154000
INTRODUCTION: Pulmonary emboli (PE) is a significant source of morbidity and mortality in the trauma patients. ...OBJECTIVE: In the present study, we evaluated the incidence of PE in severe traumatic brain injury. METHODS: Retrospective review o …
INTRODUCTION: Pulmonary emboli (PE) is a significant source of morbidity and mortality in the trauma patients. ...OBJECTIVE: I …
Therapeutic efficacy of tranexamic acid on traumatic brain injury: a systematic review and meta-analysis.
Song JX, Wu JX, Zhong H, Chen W, Zheng JC. Song JX, et al. Scand J Trauma Resusc Emerg Med. 2024 Mar 7;32(1):18. doi: 10.1186/s13049-024-01188-z. Scand J Trauma Resusc Emerg Med. 2024. PMID: 38454455 Free PMC article.
OBJECTIVE: Tranexamic acid (TXA) demonstrates therapeutic efficacy in the management of traumatic brain injury (TBI). The objective of this systematic review and meta-analysis was to evaluate the safety and effectiveness of TXA in patients with TBI. ...Howeve …
OBJECTIVE: Tranexamic acid (TXA) demonstrates therapeutic efficacy in the management of traumatic brain injury (TBI). T …
When is it safe to resume anticoagulation in traumatic brain injury?
Ng IC, Barnes C, Biswas S, Wright D, Dagal A. Ng IC, et al. Curr Opin Anaesthesiol. 2022 Apr 1;35(2):166-171. doi: 10.1097/ACO.0000000000001117. Curr Opin Anaesthesiol. 2022. PMID: 35131968 Review.
PURPOSE OF REVIEW: When to resume or initiate anticoagulation therapy following traumatic brain injury (TBI) is controversial. This summary describes the latest evidence to guide best practice. RECENT FINDINGS: Following trauma, prophylactic, and therapeutic …
PURPOSE OF REVIEW: When to resume or initiate anticoagulation therapy following traumatic brain injury (TBI) is controv …
Efficacy and safety of tranexamic acid in acute traumatic brain injury: A meta-analysis of randomized controlled trials.
Zhang M, Liu T. Zhang M, et al. Am J Emerg Med. 2024 Jun;80:35-43. doi: 10.1016/j.ajem.2024.03.005. Epub 2024 Mar 13. Am J Emerg Med. 2024. PMID: 38502985
INTRODUCTION: Tranexamic acid (TXA) holds a pivotal role in the therapeutic approach to traumatic conditions. Nevertheless, its precise influence on diminishing mortality and limiting the progression of intracranial hemorrhage (ICH) during the treatment of traumatic …
INTRODUCTION: Tranexamic acid (TXA) holds a pivotal role in the therapeutic approach to traumatic conditions. Nevertheless, its preci …
203 results