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Page 1
Coumarin-Based Aldo-Keto Reductase Family 1C (AKR1C) 2 and 3 Inhibitors.
Jonnalagadda SK, Duan L, Dow LF, Boligala GP, Kosmacek E, McCoy K, Oberley-Deegan R, Chhonker YS, Murry DJ, Reynolds CP, Maurer BJ, Penning TM, Trippier PC. Jonnalagadda SK, et al. Among authors: trippier pc. ChemMedChem. 2024 Nov 4;19(21):e202400081. doi: 10.1002/cmdc.202400081. Epub 2024 Sep 16. ChemMedChem. 2024. PMID: 38976686 Free PMC article.
Discovery of an Aldo-Keto reductase 1C3 (AKR1C3) degrader.
Carmona AV, Jonnalagadda S, Case AM, Maddeboina K, Jonnalagadda SK, Dow LF, Duan L, Penning TM, Trippier PC. Carmona AV, et al. Among authors: trippier pc. Commun Chem. 2024 Apr 29;7(1):95. doi: 10.1038/s42004-024-01177-4. Commun Chem. 2024. PMID: 38684887 Free PMC article.
The evolution of small molecule enzyme activators.
Dow LF, Case AM, Paustian MP, Pinkerton BR, Simeon P, Trippier PC. Dow LF, et al. Among authors: trippier pc. RSC Med Chem. 2023 Sep 22;14(11):2206-2230. doi: 10.1039/d3md00399j. eCollection 2023 Nov 15. RSC Med Chem. 2023. PMID: 37974956 Free PMC article. Review.
Discovery of the Next Generation of Non-peptidomimetic Neurolysin Activators with High Blood-Brain Barrier Permeability: a Pharmacokinetics Study in Healthy and Stroke Animals.
Zhang Y, Sharma S, Jonnalagadda S, Kumari S, Queen A, Esfahani SH, Archie SR, Nozohouri S, Patel D, Trippier PC, Karamyan VT, Abbruscato TJ. Zhang Y, et al. Among authors: trippier pc. Pharm Res. 2023 Nov;40(11):2747-2758. doi: 10.1007/s11095-023-03619-5. Epub 2023 Oct 13. Pharm Res. 2023. PMID: 37833570
59 results