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Year Number of Results
1977 1
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1999 2
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2001 4
2002 1
2003 2
2004 7
2005 3
2006 5
2007 1
2008 2
2009 3
2010 3
2011 6
2012 7
2013 10
2014 13
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247 results

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Page 1
Multi-omics reveal microbial determinants impacting the treatment outcome of antidepressants in major depressive disorder.
Wang Y, Zhou J, Ye J, Sun Z, He Y, Zhao Y, Ren S, Zhang G, Liu M, Zheng P, Wang G, Yang J. Wang Y, et al. Microbiome. 2023 Aug 28;11(1):195. doi: 10.1186/s40168-023-01635-6. Microbiome. 2023. PMID: 37641148 Free PMC article.
Machine learning-based multi-omics integrative analysis revealed that gut microbiota contributed to the changes in plasma metabolites and was associated with several amino acids such as tryptophan and its gut microbiota-derived metabolite, indole-3-propionic acid (I …
Machine learning-based multi-omics integrative analysis revealed that gut microbiota contributed to the changes in plasma metabolites …
Lactobacillus plantarum DR7 alleviates stress and anxiety in adults: a randomised, double-blind, placebo-controlled study.
Chong HX, Yusoff NAA, Hor YY, Lew LC, Jaafar MH, Choi SB, Yusoff MSB, Wahid N, Abdullah MFIL, Zakaria N, Ong KL, Park YH, Liong MT. Chong HX, et al. Benef Microbes. 2019 Apr 19;10(4):355-373. doi: 10.3920/BM2018.0135. Epub 2019 Mar 18. Benef Microbes. 2019. PMID: 30882244 Clinical Trial.
The consumption of DR7 (1 10(9) cfu/day) for 12 weeks reduced symptoms of stress (P=0.024), anxiety (P=0.001), and total psychological scores (P=0.022) as early as 8 weeks among stressed adults compared to the placebo group as assessed by the DASS-42 questionnaire. Plasma …
The consumption of DR7 (1 10(9) cfu/day) for 12 weeks reduced symptoms of stress (P=0.024), anxiety (P=0.001), and total psychological score …
Plasma taurine level is linked to symptom burden and clinical outcomes in post-COVID condition.
Khoramjoo M, Wang K, Srinivasan K, Gheblawi M, Mandal R, Rousseau S, Wishart D, Prasad V, Richer L, Cheung AM, Oudit GY. Khoramjoo M, et al. PLoS One. 2024 Jun 5;19(6):e0304522. doi: 10.1371/journal.pone.0304522. eCollection 2024. PLoS One. 2024. PMID: 38837993 Free PMC article.
This study aims to evaluate the association between plasma taurine levels with self-reported symptoms and adverse clinical outcomes in patients with PCC. ...Stratifying patients based on the trajectories of plasma taurine levels during six-month follow …
This study aims to evaluate the association between plasma taurine levels with self-reported symptoms and adverse clinical …
Atlas of gut microbe-derived products from aromatic amino acids and risk of cardiovascular morbidity and mortality.
Nemet I, Li XS, Haghikia A, Li L, Wilcox J, Romano KA, Buffa JA, Witkowski M, Demuth I, König M, Steinhagen-Thiessen E, Bäckhed F, Fischbach MA, Tang WHW, Landmesser U, Hazen SL. Nemet I, et al. Eur Heart J. 2023 Aug 22;44(32):3085-3096. doi: 10.1093/eurheartj/ehad333. Eur Heart J. 2023. PMID: 37342006 Free PMC article.
METHODS AND RESULTS: Stable isotope dilution mass spectrometry methods to quantitatively measure aromatic amino acids and their metabolites were used to examine sequential subjects undergoing elective diagnostic cardiac evaluation in two independent cohorts with longitudinal o …
METHODS AND RESULTS: Stable isotope dilution mass spectrometry methods to quantitatively measure aromatic amino acids and their metabolites …
Probiotic Lactobacillus Plantarum 299v decreases kynurenine concentration and improves cognitive functions in patients with major depression: A double-blind, randomized, placebo controlled study.
Rudzki L, Ostrowska L, Pawlak D, Małus A, Pawlak K, Waszkiewicz N, Szulc A. Rudzki L, et al. Psychoneuroendocrinology. 2019 Feb;100:213-222. doi: 10.1016/j.psyneuen.2018.10.010. Epub 2018 Oct 16. Psychoneuroendocrinology. 2019. PMID: 30388595 Clinical Trial.
Cognitive functions were assessed using the Attention and Perceptivity Test (APT), Stroop Test parts A and B, Ruff Figural Fluency Test (RFFT), Trail Making Test (TMT) Parts A and B and the California Verbal Learning Test (CVLT). Biochemical parameters such as tryptophan ( …
Cognitive functions were assessed using the Attention and Perceptivity Test (APT), Stroop Test parts A and B, Ruff Figural Fluency Test (RFF …
Metabolomics in sickle cell disease: Current knowledge and gaps - A scoping review.
van der Veen S, Jans JJM, van Beers EJ, Biemond BJ, Bartolucci P, Boaro MP, Collado Gimbert A, Colombatti R, D'Agnolo M, Fijnvandraat KJ, Idrizovic A, Kountouris P, Mañú Pereira M, Mezzalira E, Rab MAE, Rijneveld AW, Sanavia T, Verhoeven-Duif NM, Cnossen MH. van der Veen S, et al. Blood Rev. 2025 Nov;74:101338. doi: 10.1016/j.blre.2025.101338. Epub 2025 Sep 6. Blood Rev. 2025. PMID: 40945973 Free article.
We conducted a scoping review on associations between blood metabolites, SCD-related complications, and therapies in studies analyzing 10 metabolites in red blood cells, whole blood, and plasma. Lipidomics-focused studies were excluded. Fifteen studies were included, focu …
We conducted a scoping review on associations between blood metabolites, SCD-related complications, and therapies in studies analyzing 10 m …
Plasma Tryptophan-Kynurenine Pathway Metabolites and Risk for Progression to End-Stage Kidney Disease in Patients With Type 2 Diabetes.
Liu JJ, Ching J, Wee HN, Liu S, Gurung RL, Lee J, M Y, Zheng H, Lee LS, Ang K, Shao YM, Kovalik JP, Subramaniam T, Sum CF, Sharma K, Kestenbaum BR, Lim SC. Liu JJ, et al. Diabetes Care. 2023 Dec 1;46(12):2223-2231. doi: 10.2337/dc23-1147. Diabetes Care. 2023. PMID: 37796480 Free PMC article.
OBJECTIVE: We sought to study the associations between plasma metabolites in the tryptophan-kynurenine pathway and the risk of progression to end-stage kidney disease (ESKD) in patients with type 2 diabetes. ...The secondary outcome was annual eGFR decline. R …
OBJECTIVE: We sought to study the associations between plasma metabolites in the tryptophan-kynurenine pathway and the risk of …
Platelet serotonin and plasma tryptophan in depressed patients: effect of drug treatment and clinical outcome.
Karege F, Widmer J, Bovier P, Gaillard JM. Karege F, et al. Neuropsychopharmacology. 1994 May;10(3):207-14. doi: 10.1038/npp.1994.23. Neuropsychopharmacology. 1994. PMID: 7916918 Free article. Clinical Trial.

Platelet serotonin and plasma tryptophan were studied in healthy subjects and in depressed patients before and during their antidepressant drug treatment. ...Antidepressant drugs treatment decreased platelet 5-HT level (ANOVA F = 8.27, p < .001) whatever the c

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Platelet serotonin and plasma tryptophan were studied in healthy subjects and in depressed patients before and during their an …
Immunodiagnostic plasma amino acid residue biomarkers detect cancer early and predict treatment response.
Tang C, Corredeira P, Casimiro S, Shi Q, Han Q, Sukdao W, Cavaco A, Melo-Alvim C, Matos CO, Abreu C, Walsh S, Nogueira-Costa G, Ribeiro L, Sousa R, Barradas AL, Fonseca JE, Costa L, Yates EV, Bernardes GJL. Tang C, et al. Nat Commun. 2025 Jul 14;16(1):6474. doi: 10.1038/s41467-025-61685-2. Nat Commun. 2025. PMID: 40659634 Free PMC article.
We identify a panel of amino acid residue biomarkers providing a signature of cancer-specific immune activation associated with tumour development and distinct from autoimmune and infectious diseases, measurable optically in neat blood plasma, and validate within N = 170 p …
We identify a panel of amino acid residue biomarkers providing a signature of cancer-specific immune activation associated with tumour devel …
Probing the oral-brain connection: oral microbiome patterns in a large community cohort with anxiety, depression, and trauma symptoms, and periodontal outcomes.
Malan-Müller S, Vidal R, O'Shea E, Montero E, Figuero E, Zorrilla I, de Diego-Adeliño J, Cano M, García-Portilla MP, González-Pinto A, Leza JC. Malan-Müller S, et al. Transl Psychiatry. 2024 Oct 5;14(1):419. doi: 10.1038/s41398-024-03122-4. Transl Psychiatry. 2024. PMID: 39368974 Free PMC article.
Functional prediction analysis revealed a potential role for tryptophan metabolism/degradation in the oral-brain axis, which was confirmed by lower plasma serotonin levels across symptomatic groups. This study sheds light on the intricate interplay between oral micr …
Functional prediction analysis revealed a potential role for tryptophan metabolism/degradation in the oral-brain axis, which was conf …
247 results