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Involvement of estrogen receptors in the resveratrol-mediated increase in dopamine transporter in human dopaminergic neurons and in striatum of female mice.
Di Liberto V, Mäkelä J, Korhonen L, Olivieri M, Tselykh T, Mälkiä A, Do Thi H, Belluardo N, Lindholm D, Mudò G. Di Liberto V, et al. Among authors: tselykh t. Neuropharmacology. 2012 Feb;62(2):1011-8. doi: 10.1016/j.neuropharm.2011.10.010. Epub 2011 Oct 24. Neuropharmacology. 2012. PMID: 22041555
Treatment with resveratrol (RSV) has been shown to protect vulnerable neurons after various brain injuries and in neurodegenerative diseases. The mechanisms for the effects of RSV in brain are not fully understood, but RSV may affect the expression of various gene products …
Treatment with resveratrol (RSV) has been shown to protect vulnerable neurons after various brain injuries and in neurodegenerative d …
Transgenic expression and activation of PGC-1alpha protect dopaminergic neurons in the MPTP mouse model of Parkinson's disease.
Mudò G, Mäkelä J, Di Liberto V, Tselykh TV, Olivieri M, Piepponen P, Eriksson O, Mälkiä A, Bonomo A, Kairisalo M, Aguirre JA, Korhonen L, Belluardo N, Lindholm D. Mudò G, et al. Among authors: tselykh tv. Cell Mol Life Sci. 2012 Apr;69(7):1153-65. doi: 10.1007/s00018-011-0850-z. Epub 2011 Oct 8. Cell Mol Life Sci. 2012. PMID: 21984601 Free PMC article.
We show here that transgenic mice overexpressing PGC-1alpha in dopaminergic neurons are resistant against cell degeneration induced by the neurotoxin MPTP. The increase in neuronal viability was accompanied by elevated levels of mitochondrial antioxidants SOD2 and T …
We show here that transgenic mice overexpressing PGC-1alpha in dopaminergic neurons are resistant against cell degeneration induced b …